CN
Search Within
91827
Applied Filters:
Keyword:'91827'
Showing 1-30 of 120 results for "91827" within Papers
Quantification of biotin in feed, food, tablets, and premixes using HPLC?MS/MS
Holler U, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 831(1-2), 8-16 (2006)
Timothy Sanchez et al.
Methods in enzymology, 524, 205-224 (2013-03-19)
From motility of simple protists to determining the handedness of complex vertebrates, highly conserved eukaryotic cilia and flagella are essential for the reproduction and survival of many biological organisms. Despite extensive studies, the exact mechanism by which individual components coordinate
Konstantina Papadia et al.
Journal of biomedical nanotechnology, 10(5), 871-876 (2014-04-17)
The biotin-Streptavidin (STREP) technique for attachment of monoclonal antibodies (mAbs) (or other ligand types) on liposome surface offers high attachment yield, however it is time consuming and expensive due to the number of steps used and the consumption of large
Pascal Loyer et al.
International journal of pharmaceutics, 454(2), 727-737 (2013-06-12)
Amphiphilic derivatives of poly(benzyl malate) were synthesized and characterized with the aim of being used as degradable and biocompatible building blocks for the design of functional nanoparticles (NPs). An anti-cancer model drug, doxorubicin, has been successfully encapsulated into the prepared
T I El-Hajj et al.
Neuropediatrics, 39(5), 268-271 (2009-03-19)
Biotin-responsive basal ganglia disease is a rare entity of which 10 cases have been reported in the literature. We report a case of biotin-responsive basal ganglia disease with similarities and differences compared to the previously reported cases by Ozand et
Ria M Cooke et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(13), 5626-5637 (2013-03-29)
Nitric oxide (NO) is an important signaling molecule with a variety of functions in the CNS, including a potential role in modulating neuronal growth and synapse formation. In the present study, we used tractable, identified neurons in the CNS of
A Abd El-Wahab et al.
Poultry science, 92(7), 1774-1782 (2013-06-19)
Foot pad dermatitis (FPD) is a widespread problem in poultry production and constitutes a welfare issue. The objective of this study was to test potentially prophylactic effects of higher biotin and Zn levels in the diet of broilers exposed to
K Dzitko et al.
Experimental parasitology, 134(2), 216-219 (2013-03-19)
Taking into account the literature reports on the involvement of prolactin (PRL) in the regulation of immunity against Toxoplasma gondii, we decided to check whether this parasite has the ability to bind the lactotrophic hormone. We examined T. gondii binding
Majid Alfadhel et al.
Orphanet journal of rare diseases, 8, 83-83 (2013-06-08)
Biotin-responsive basal ganglia disease (BBGD) is an autosomal recessive neurometabolic disorder. It is characterized by sub acute encephalopathy with confusion, seizure, dysarthria and dystonia following a history of febrile illness. If left untreated with biotin, the disease can progress to
Yoshikazu Ogawa et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 41(4), 517-522 (2014-04-20)
Gefitinib anderlotinib, which are epidermal growth factor receptor(EGFR)tyrosine kinase inhibitors(TKIs), have been usedfor the treatment of inoperable andrecurrent non-small cell lung cancer(NSCLC)patients. These drugs are known to cause a skin rash, one of the major side effects, at a high
John E Cronan et al.
Current opinion in chemical biology, 15(3), 407-413 (2011-03-26)
Biotin synthesis requires the C7 α,ω-dicarboxylic acid, pimelic acid. Although pimelic acid was known to be primarily synthesized by a head to tail incorporation of acetate units, the synthetic mechanism was unknown. It has recently been demonstrated that in most
Jacob G Vineberg et al.
Journal of medicinal chemistry, 57(13), 5777-5791 (2014-06-06)
Novel tumor-targeting dual-warhead conjugates, 2 (DW-1) and 3 (DW-2), which consist of a next-generation taxoid, 1 (SB-T-1214), and camptothecin as two warheads, self-immolative disulfide linkers for drug release, biotin as the tumor-targeting moiety, and 1,3,5-triazine as the tripod splitter module
Sari Pihlasalo et al.
Analytical biochemistry, 440(1), 6-8 (2013-05-25)
A stable liposome-based time-resolved luminescence resonance energy transfer (TR-LRET) assay was developed based on the interaction of biotinylated lipids and streptavidin. Eu(3+) ion chelated to 4,4,4-trifluoro-1-(2-naphthalenyl)-1,3-butanedione and trioctylphosphine oxide was incorporated into liposomes. Acceptor-labeled streptavidin bound to biotinylated lipids of
Alyse M DeHaan et al.
The Prostate, 69(5), 528-537 (2009-01-15)
Bone metastasis occurs frequently in advanced prostate cancer (PCa) patients; however, it is not known why this happens. The epidermal growth factor receptor (EGFR) ligand EGF is available to early stage PCa; whereas, TGF-alpha is available when PCa metastasizes. Since
Jon-Paul Bingham et al.
Bioconjugate chemistry, 17(3), 689-699 (2006-05-18)
Iberiotoxin (IbTx) is a scorpion venom peptide that inhibits BK Ca2+-activated K+ channels with high affinity and specificity. Automated solid-phase synthesis was used to prepare a biotin-labeled derivative (IbTx-LC-biotin) of IbTx by substitution of Asp19 of the native 37-residue peptide
Yu-Chu Chang et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 219-224 (2013-12-25)
The thermodynamic stability of proteins is typically measured at high denaturant concentrations and then extrapolated back to zero denaturant conditions to obtain unfolding free energies under native conditions. For membrane proteins, the extrapolations are fraught with considerable uncertainty as the
Stéphane Mann et al.
Biochimica et biophysica acta, 1814(11), 1459-1466 (2010-12-25)
The four last steps of biotin biosynthesis, starting from pimeloyl-CoA, are conserved among all the biotin-producing microorganisms. Two enzymes of this pathway, the 8-amino-7-oxononanoate synthase (AONS) and the 7,8-diaminopelargonic acid aminotransferase (DAPA AT) are dependent on pyridoxal-5'-phosphate (PLP). This review
José Antonio Nieto Rodríguez
Medicina clinica, 139 Suppl 2, 19-23 (2013-03-27)
In the last few years, several phase III clinical trials of new drug treatments for deep vein thrombosis (DVT) have been carried out or are about to finish. These drugs have a predictable and reliable pharmacokinetic and pharmacodynamic response and
Arun Sreekumar et al.
Nature, 457(7231), 910-914 (2009-02-13)
Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion and disease aggressiveness. Although gene and protein expression have
L P Thuy et al.
Clinica chimica acta; international journal of clinical chemistry, 202(3), 191-197 (1991-10-31)
A double antibody technique has been developed to separate free biotin from bound biotin after competitive binding of [3H]biotin and unlabelled biotin to avidin. Antiavidin goat antibody was added followed by the addition of antigoat IgG antibody linked to agarose.
Wei Ren et al.
Biosensors & bioelectronics, 49, 380-386 (2013-06-29)
A versatile flow cytometric bead assay (CBA) is developed for sensitive DNA detection by integrating the advantages of hybridization chain reaction (HCR) for enzyme-free signal amplification, flow cytometry for robust and rapid signal readout as well as magnetic beads (MBs)
Adam D Lietzan et al.
Archives of biochemistry and biophysics, 544, 75-86 (2013-11-05)
Biotin-dependent enzymes catalyze carboxylation, decarboxylation and transcarboxylation reactions that participate in the primary metabolism of a wide range of organisms. In all cases, the overall reaction proceeds via two half reactions that take place in physically distinct active sites. In
Lezanne Ooi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(14), 6041-6046 (2013-04-05)
We have identified a new signaling role for nitric oxide (NO) in neurons from the trigeminal ganglia (TG). We show that in rat sensory neurons from the TG the NO donor, S-nitroso-N-acetyl-dl-penicillamine, inhibited M-current. This inhibitory effect was blocked by
Christina M Van Itallie et al.
The Journal of biological chemistry, 288(19), 13775-13788 (2013-04-05)
Biotin ligase tagging with ZO-1 was applied to identify a more complete tight junction proteome. Identical but also different proteins and functional networks were identified near the N and C ends of ZO-1. The ends of ZO-1 are embedded in
Determination of biotin levels in cerebrospinal fluid samples.
E Livaniou et al.
Journal of pharmaceutical and biomedical analysis, 21(4), 875-879 (2000-03-04)
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have
Liang Tong
Cellular and molecular life sciences : CMLS, 70(5), 863-891 (2012-08-08)
Biotin-dependent carboxylases include acetyl-CoA carboxylase (ACC), propionyl-CoA carboxylase (PCC), 3-methylcrotonyl-CoA carboxylase (MCC), geranyl-CoA carboxylase, pyruvate carboxylase (PC), and urea carboxylase (UC). They contain biotin carboxylase (BC), carboxyltransferase (CT), and biotin-carboxyl carrier protein components. These enzymes are widely distributed in nature
D Wang et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83(3-4), 179-189 (2008-10-11)
Angiogenesis, or neovascularization, is known to play an important role in the neoplastic progression leading to metastasis. CD31 or Factor VIII-related antigen (F VIII RAg) immunohistochemistry is widely used in experimental studies for quantifying tumor neovascularization in immunocompromised animal models
Christopher Eginton et al.
Biochemistry, 52(38), 6595-6600 (2013-08-30)
Solvent reorganization can contribute significantly to the energetics of protein-protein interactions. However, our knowledge of the magnitude of the energetic contribution is limited, in part, by a dearth of quantitative experimental measurements. The biotin repressor forms a homodimer as a
Elena de Juan-Franco et al.
Talanta, 114, 268-275 (2013-08-21)
We have implemented a Surface Plasmon Resonance (SPR) immunosensor based on a sandwich assay for the simultaneous detection of the two main hGH isoforms, of 22 kDa (22K) and 20 kDa (20K). An oriented-antibody sensor surface specific for both hormone
Page 1 of 4