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Showing 1-30 of 1715 results for "95-50-1" within Papers
Xiangmin He et al.
Zhonghua yi xue za zhi, 82(10), 685-688 (2002-07-23)
To investigate the polymorphisms of interleukin-1B (IL-1B) promotor region 31 C/T and interleukin-1 receptor antagonist (IL-1RN) gene and the relationship between the genotype of IL-1 and IL-1RN and susceptibility to gastric cancer in Chinese population. Genomic DNA was extracted from
B Yu et al.
The British journal of dermatology, 163(5), 935-940 (2010-07-14)
Systemic lupus erythematosus (SLE) is a complex genetic disease; the histamine H4 receptor (HRH4) has been shown to be related to different kinds of autoimmune disorders; and copy number variations (CNVs) have been found to be associated with various types
G Piffaretti et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 53(6), 793-801 (2017-03-28)
To analyse the results and review the literature about thoracic aortic endovascular repair (TEVAR) for type B acute aortic dissection (TBAAD) complicated by descending thoracic aortic aneurysm (DTA) in the hyperacute or acute phases. This was a multicentre, observational descriptive
R S Herbst et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 30(2), 281-289 (2019-01-19)
In KEYNOTE-010, pembrolizumab versus docetaxel improved overall survival (OS) in patients with programmed death-1 protein (PD)-L1-positive advanced non-small-cell lung cancer (NSCLC). A prespecified exploratory analysis compared outcomes in patients based on PD-L1 expression in archival versus newly collected tumor samples
Kerstin Wagner et al.
Carcinogenesis, 27(9), 1867-1875 (2006-04-12)
The regulation of growth hormone 1 (GH1) and insulin-like-growth factor-1 (IGF-1) release is under the influence of three pituitary hormones [growth hormone releasing hormone (GHRH), ghrelin (GHRL) and somatostatin (SST)], which act in an autocrine/paracrine fashion in the breast. By
Sara Aileen Madanikia et al.
American journal of medical genetics. Part A, 158A(12), 3056-3060 (2012-11-21)
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder associated with increased risk for neoplasms. Two studies in the United Kingdom have indicated that women with NF1 (particularly women under 50) may also be at increased risk of breast
A H Lichtman et al.
The Journal of pharmacology and experimental therapeutics, 298(3), 1007-1014 (2001-08-16)
The goal of the present study was to elucidate the relationship between cannabinoid and opioid systems in drug dependence. The CB(1) cannabinoid receptor antagonist SR 141716A precipitated both paw tremors and head shakes in four different mouse strains that were
Nicole Y Marden et al.
The Biochemical journal, 391(Pt 3), 631-640 (2005-07-13)
The human cytochrome P450 2J2 (CYP2J2) generates cytoprotective epoxyeicosatrienoic acids from arachidonic acid. Expression of CYP2J2 is decreased in hypoxia, and the resultant decrease in CYP2J2-derived epoxyeicosanoids may contribute to the pathogenesis of cardiac ischaemia. Recent studies have indicated that
Daniel E Jonas et al.
JAMA, 311(18), 1889-1900 (2014-05-16)
Alcohol use disorders cause substantial morbidity and early mortality yet remain greatly undertreated. Medications are considerably underused. To conduct a systematic review and meta-analysis of the benefits and harms of medications (US FDA-approved and others) for adults with alcohol use
Marsha A Raebel et al.
JAMA, 310(13), 1369-1376 (2013-10-03)
Obesity is associated with chronic noncancer pain. It is not known if opioid use for chronic pain in obese individuals undergoing bariatric surgery is reduced. To determine opioid use following bariatric surgery in patients using opioids chronically for pain control
Sunil K Agrawal et al.
Pediatric research, 65(6), 675-680 (2009-05-12)
Genetic factors are implicated in pathogenesis of neonatal hyperbilirubinemia. In this nested case-control study, we determined 1) frequency of thymine-adenine (TA)n promoter polymorphism and Gly71Arg mutation in uridine diphosphoglucuronate-glucuronosyltransferase 1A1 (UGT1A1) gene in neonates > or =35-wk gestation presenting with
Chloe A Teasdale et al.
Journal of the International AIDS Society, 21(8), e25168-e25168 (2018-08-11)
There are limited data on viral suppression (VS) in children with HIV receiving antiretroviral therapy (ART) in routine care in low-resource settings. We examined VS in a cohort of children initiating ART in routine HIV care in Eastern Cape Province
K Sugino et al.
Endocrinology, 130(2), 789-796 (1992-02-01)
High molecular mass forms [95 kilodaltons (kDa)] of bovine inhibin-A as well as the known forms of intermediate (55 kDa) and low (32 kDa) mass were purified from bovine follicular fluid by ion exchange chromatography on DEAE-Sepharose, immunoaffinity chromatography using
José R Santos et al.
The Journal of antimicrobial chemotherapy, 70(4), 1124-1129 (2014-12-20)
Data on the efficacy of simplifying therapy using darunavir/ritonavir and lopinavir/ritonavir monotherapy in clinical practice remain limited. A retrospective single-centre study including patients initiating darunavir/ritonavir or lopinavir/ritonavir monotherapy with a plasma HIV-1 viral load (pVL) <50 copies/mL and at least
Lynn Y L Huang et al.
Cancer chemotherapy and pharmacology, 74(3), 511-520 (2014-07-21)
Highly expressed in cancer protein 1 (Hec1) is an oncogene and a promising molecular target for novel anticancer drugs. The purpose of this study was to evaluate the potential of a Hec1 inhibitor, TAI-95, as a treatment for primary liver
R Hui et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 28(4), 874-881 (2017-02-09)
Pembrolizumab improved survival as first- and second-line therapy compared with chemotherapy in patients with highly programmed death ligand 1 (PD-L1) expressing advanced non-small cell lung cancer (NSCLC). We report the long-term safety and clinical activity of pembrolizumab as first-line therapy
Jesper J Linde et al.
Journal of the American College of Cardiology, 75(5), 453-463 (2020-02-08)
In patients with non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary pathology may range from structurally normal vessels to severe coronary artery disease. The purpose of this study was to test if coronary computed tomography angiography (CTA) may be used to
F Megiorni et al.
The British journal of dermatology, 165(4), 823-827 (2011-06-23)
Alopecia areata (AA) is a multifactorial disease characterized by hair loss especially from the scalp. As for other autoimmune conditions, the major histocompatibility complex (HLA) region is associated with AA susceptibility. To provide evidence for the association of specific HLA-DQB1
J-A Epinette et al.
The bone & joint journal, 95-B(12), 1610-1616 (2013-12-03)
We report a multicentre prospective consecutive study assessing the long-term outcome of the proximally hydroxyapatite (HA)-coated ABG II monobloc femoral component in a series of 1148 hips in 1053 patients with a mean age at surgery of 64.77 years (22
H G Sprenger et al.
HIV medicine, 16(2), 122-131 (2014-12-05)
The aim of the study was to test the antiviral efficacy of a triple nucleoside reverse transcriptase inhibitor (NRTI) regimen, with potential beneficial metabolic effects, as maintenance therapy after induction with dual NRTIs and a boosted protease inhibitor (PI). An
Yu-Chao Ni et al.
Asian journal of andrology, 24(2), 154-160 (2021-08-13)
Corticosteroid switching can reverse abiraterone resistance in some patients with metastatic castration-resistant prostate cancer (mCRPC). Here, we investigated the potential biomarkers for predicting the efficacy of corticosteroid switching during treatment with abiraterone acetate (AA). We retrospectively analyzed 101 mCRPC patients
Sébastien Briolant et al.
Antimicrobial agents and chemotherapy, 54(9), 3537-3544 (2010-06-16)
We have analyzed the profiles of 23 of Plasmodium falciparum strains for their in vitro chemosusceptibilities to piperaquine (PPQ), dihydroartemisinin (DHA), chloroquine, monodesethylamodiaquine, quinine, mefloquine, lumefantrine, atovaquone, pyrimethamine, and doxycycline (DOX) in association with polymorphisms in genes involved in quinoline
X Wang et al.
American journal of medical genetics. Part A, 158A(12), 3061-3064 (2012-09-12)
Neurofibromatosis type 1 (NF1) is one of the most common cancer predisposing syndromes with an incidence of 1 in 3,500 worldwide. Certain neoplasms or malignancies are over-represented in individuals with NF1; however, an increased risk of breast cancer has not
Tita Husnitawati Madjid et al.
Diagnostics (Basel, Switzerland), 10(6) (2020-06-06)
Endometriosis is a gynecological disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Remodeling of the extracellular matrix (ECM) is a prerequisite for tissue implantation. The presence of matrix metalloproteinase (MMP) and its inhibitor, tissue inhibitor of
Mohamed Zeriouh et al.
Journal of cardiothoracic surgery, 10, 180-180 (2015-12-08)
The aim of this study was to determine whether intermittent warm blood cardioplegia (IWC) is associated with comparable myocardial protection compared to cold blood cardioplegia (ICC) in patients undergoing elective vs. emergent CABG procedures. Out of 2292 consecutive patients who
Oliver Teuffel et al.
British journal of haematology, 161(2), 192-203 (2013-02-13)
This systematic review and meta-analysis compared the efficacy of different anthracyclines and anthracycline dosing schedules for induction therapy in acute myeloid leukaemia in children and adults younger than 60 years of age. Twenty-nine randomized controlled trials were eligible for inclusion in
Shalender Bhasin et al.
JAMA, 307(9), 931-939 (2012-03-08)
Steroid 5α-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5α-dihydrotestosterone (DHT) in mediating testosterone's effects on muscle, sexual function, erythropoiesis, and other androgen-dependent processes remains poorly understood. To determine whether testosterone's effects
Anupam Basuray et al.
Circulation, 129(23), 2380-2387 (2014-05-07)
We hypothesized that patients with heart failure (HF) who recover left ventricular function (HF-Recovered) have a distinct clinical phenotype, biology, and prognosis compared with patients with HF with reduced ejection fraction (HF-REF) and those with HF with preserved ejection fraction
Patrick Schöffski et al.
European journal of cancer (Oxford, England : 1990), 134, 62-74 (2020-05-30)
Gastrointestinal stromal tumour (GIST) is commonly treated with tyrosine kinase inhibitors (TKIs), but most patients ultimately develop secondary resistance. Cabozantinib, a multi-targeted TKI inhibitor, has activity in patient-derived GIST mouse xenograft models and can overcome compensatory MET signalling occurring on
Robert W Haile et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 15(10), 1863-1870 (2006-10-06)
Understanding the effect of oral contraceptives on risk of breast cancer in BRCA1 or BRCA2 mutation carriers is important because oral contraceptive use is a common, modifiable practice. We studied 497 BRCA1 and 307 BRCA2 mutation carriers, of whom 195
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