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Showing 31-60 of 168 results for "95-71-6" within Papers
P M Lago et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 16(5), 656-659 (2012-03-14)
Interleukin (IL) 10 and interferon-gamma (IFN-) levels in induced sputum supernatants of 21 tuberculosis (TB) patients at diagnosis and during chemotherapy were correlated to recurrence rates. IL-10 decreased until day 60 of treatment (T60), and between T60 and T180 it
Michelle Furtado et al.
British journal of haematology, 168(1), 55-62 (2014-08-26)
The proteasome inhibitor, bortezomib, potentially increases cell sensitivity to chemotherapy. This study was performed to determine the overall response rate (ORR), overall survival (OS), progression-free survival (PFS) and toxicity of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) compared to CHOP +
Man-Sun Sy et al.
Cancer biomarkers : section A of Disease markers, 10(6), 251-258 (2011-01-01)
Pancreatic ductal adenocarcinoma (PDAC) is an important cause of cancer death with no clear prognostic biomarker. Expression of prion (PrP) has been reported to be a marker of poor prognosis in a series of Caucasian PDAC cases. We determined the
A J Davies et al.
Leukemia, 19(8), 1459-1465 (2005-05-20)
The role of TP53 mutation in transformation of follicular lymphoma (FL) to diffuse large B-cell lymphoma (t-FL) was examined in a panel of 91 lymph node biopsies derived from 29 patients pre- and post-transformation. The entire TP53 coding sequence was
Tiziana Larussa et al.
European journal of internal medicine, 23(3), 273-277 (2012-03-06)
Gene polymorphism of thiopurine methyltransferase (TPMT) correlates with decreased enzyme activity which determines a significant risk of adverse effect reactions (ADR) in patients treated with thiopurines. The aim of this study was to investigate TPMT genotype and phenotype status in
Giancarlo Agnelli et al.
The New England journal of medicine, 369(9), 799-808 (2013-07-03)
Apixaban, an oral factor Xa inhibitor administered in fixed doses, may simplify the treatment of venous thromboembolism. In this randomized, double-blind study, we compared apixaban (at a dose of 10 mg twice daily for 7 days, followed by 5 mg
Alice T Shaw et al.
The Lancet. Oncology, 12(11), 1004-1012 (2011-09-22)
ALK gene rearrangement defines a new molecular subtype of non-small-cell lung cancer (NSCLC). In a recent phase 1 clinical trial, the ALK tyrosine-kinase inhibitor (TKI) crizotinib showed marked antitumour activity in patients with advanced, ALK-positive NSCLC. To assess whether crizotinib
Sureyya B Gorkem et al.
AJR. American journal of roentgenology, 200(6), 1352-1357 (2013-05-25)
The purpose of this study was to investigate the efficacy of thoracic MRI with fast imaging sequences without contrast administration at 1.5 T for evaluating thoracic abnormalities by comparing MRI findings with contrast-enhanced MDCT findings. A prospective study included consecutively
Andrew Bivard et al.
Circulation, 135(5), 440-448 (2016-12-15)
We pooled 2 clinical trials of tenecteplase compared with alteplase for the treatment of acute ischemic stroke, 1 that demonstrated superiority of tenecteplase and the other that showed no difference between the treatments in patient clinical outcomes. We tested the
Xianlin Ye et al.
Transfusion, 60(7), 1476-1482 (2020-05-03)
Hepatitis B virus (HBV) infection is one of the major concerns for the safety of blood transfusion in high-prevalent countries such as in China. Prior studies outside of China have shown hepatitis B surface antigen (HBsAg) false-reactive rate of 0.02%
Mohamed A Bedaiwy et al.
Obstetrics and gynecology, 108(1), 162-168 (2006-07-04)
Although most women experience retrograde menses during their reproductive life, endometriosis develops only in a small percentage. We hypothesized that persistence of a fibrin matrix in peritoneal pockets, as a result of hypofibrinolysis, could allow menstrually deposited endometrial fragments to
Debby M E I Hellebrekers et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(12), 3990-3997 (2009-06-11)
The transcription factors GATA4 and GATA5 are involved in gastrointestinal development and are inactivated by promoter hypermethylation in colorectal cancer. Here, we evaluated GATA4/5 promoter methylation as potential biomarkers for noninvasive colorectal cancer detection, and investigated the role of GATA4/5
Jonathan Krakoff et al.
Diabetes care, 26(6), 1745-1751 (2003-05-27)
To examine the association between adiponectin, a known predictor of diabetes in Pima Indians, and markers of inflammation and endothelial function in nondiabetic subjects and to assess whether these markers predict later diabetes in a case-control study within a longitudinal
Aiyun Yuan et al.
Inflammation, 38(2), 728-735 (2014-08-02)
Interleukin-6 (IL-6), as one of pro-inflammatory cytokines, plays a key role in Enterovirus 71 (EV71) encephalitis. We investigated the association of IL-6-572C/G polymorphism and serum or cerebrospinal fluid (CSF) IL-6 level with EV71 encephalitis in patients with hand, foot, and
Cristina Masseria et al.
Human vaccines & immunotherapeutics, 11(5), 1175-1183 (2015-02-26)
The Advisory Committee on Immunization Practices recommends administering diphtheria, tetanus and acellular pertussis (DTaP) vaccines to children at 2, 4, 6, 15-18 months, and 4-6 y of age; preferably with the same-brand vaccine for the whole series. We estimated age-appropriate
Chih-Yu Chi et al.
Blood, 121(8), 1357-1366 (2012-12-18)
Adult patients with disseminated nontuberculous mycobacterial (dNTM) infections usually have severe immune system defects. Recently, several studies have shown that anti-IFN-γ autoantibodies may play an important role in the pathogenicity of dNTM infections. A considerable proportion of reported cases of
Guilherme A F Rollin et al.
Clinical endocrinology, 82(6), 793-800 (2014-11-08)
To analyse the performance of the desmopressin (DDAVP) test in the diagnosis of Cushing's disease (CD). This was a prospective cohort study of 124 patients with suspected hypercortisolism who were recruited from an outpatient endocrinology clinic and investigated for Cushing's
Leonardo Lorente et al.
Journal of critical care, 30(4), 860-860 (2015-04-15)
Melatonin in septic patients has been scarcely explored and only in studies of small sample size (maximum 20 patients). Thus, the objective of this study was to determine whether serum melatonin levels are associated with severity, oxidant and inflammatory state
A VanderWalde et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 18(8), 1273-1280 (2012-02-07)
Patients with high-risk locally advanced/inflammatory and oligometastatic (≤3 sites) breast cancer frequently relapse or experience early progression. High-dose chemotherapy combined with peripheral stem cell rescue may prolong progression-free survival/relapse-free survival (PFS/RFS) and overall survival (OS). In this study, patients initiated
Abdurrahman Kadayifci et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 23(1), 8-13 (2012-04-17)
Helicobacter pylori eradication rates with standard triple regimens are worsening, and alternative treatments are urgently needed in some populations. The present study aimed to compare the efficacy of bismuth-based quadruple and concomitant regimens. Consecutive Helicobacter pylori-positive patients with non-ulcer dyspepsia
S-C Chang et al.
The Journal of hospital infection, 83(4), 288-293 (2013-02-13)
Human enterovirus 71 (HEV71) infections are a significant public health threat in the Asia-Pacific region and occasionally cause severe neurological complications and even death in children. Although good hand hygiene is important for controlling infection, relevant data regarding the efficacy
Pamela L Valentino et al.
Inflammatory bowel diseases, 21(12), 2848-2856 (2015-08-15)
Liver enzymes (LEs) abnormalities associated with pediatric inflammatory bowel diseases (IBD) are understudied. We undertook to describe the development and associations of abnormal LEs in pediatric IBD. We ascertained a cohort of 300 children with IBD and collected retrospective data.
Florian Part et al.
Journal of hazardous materials, 394, 122477-122477 (2020-04-03)
Semiconductor quantum dots (QDs) are nanocrystals used in diverse optoelectronics. At the end of their useful life they are likely to end up in landfills, where they could be mobilzed by infiltrating rain water. In this work, spectroscopic and light
Nicolas von Ahsen et al.
Clinical chemistry, 51(12), 2282-2288 (2005-10-11)
Azathioprine (aza) therapy is beneficial in the treatment of inflammatory bowel disease, but 10%-30% of patients cannot tolerate aza therapy because of adverse drug reactions. Thiopurine S-methyltransferase (TPMT) deficiency predisposes to myelotoxicity, but its association with other side effects is
Elisabeth Jobs et al.
Diabetes care, 36(1), 163-165 (2012-08-28)
To investigate associations between serum cathepsin S, impaired insulin sensitivity, defective insulin secretion, and diabetes risk in a community-based sample of elderly men without diabetes. Serum cathepsin S, insulin sensitivity (euglycemic-hyperinsulinemic clamp), and insulin secretion (early insulin response during an
Nicolas Leveziel et al.
Investigative ophthalmology & visual science, 53(8), 5004-5009 (2012-06-09)
Nonsyndromic high myopia, defined by a refractive error greater than -6 diopters (D), is associated with an increased risk of macular choroidal neovascularization (CNV), a vision-threatening complication. The aim of this study was to investigate whether genetic factors associated with
R John Baier et al.
BMC medicine, 4, 10-10 (2006-04-14)
Genetic variation in the innate immune system of the host may play a role in determining the risk of developing infection, as well as outcome from infection. Infectious complications were retrospectively determined in 293 (233 African-American (AA), 57 Caucasian and
Vincent Wai-Sun Wong et al.
International journal of cancer, 124(12), 2766-2770 (2009-03-10)
Increased interleukin-6 (IL-6) production is implicated in the pathogenesis of hepatocellular carcinoma (HCC) in animal models. Although previous studies showed that HCC patients had higher serum IL-6 level at the time of diagnosis, it is unclear if the cytokine contributes
Turan Calhan et al.
Helicobacter, 18(5), 378-383 (2013-04-23)
An ideal second-line therapeutic regimen for the treatment of patients who do not respond to standard triple therapy is currently being investigated. In this study, we aimed to investigate the efficacy of two levofloxacin-containing second-line therapies for Helicobacter pylori (H.
Mukti Sharma et al.
Clinical endocrinology, 75(5), 642-649 (2011-05-24)
To determine the frequency distribution of LMNA 1908C>T SNP and its association with generalized obesity, abdominal obesity and coexistent metabolic disorders in nondiabetic Asian Indians living in a metropolitan city of north India. A cross-sectional population-based study of LMNA 1908C>T
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