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Showing 1-30 of 80 results for "98-44-2" within Papers
Mark S Sulkowski et al.
The New England journal of medicine, 370(3), 211-221 (2014-01-17)
All-oral combination therapy is desirable for patients with chronic hepatitis C virus (HCV) infection. We evaluated daclatasvir (an HCV NS5A replication complex inhibitor) plus sofosbuvir (a nucleotide analogue HCV NS5B polymerase inhibitor) in patients infected with HCV genotype 1, 2
Marek Pruszyński et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 70(6), 974-979 (2012-04-03)
The positron-emitting radionuclide (44)Sc with a half-life of 3.97 h and a β(+) branching of 94.3% is of potential interest for clinical PET. As so far it is available from a (44)Ti/(44)Sc generator in Mainz, where long-lived (44)Ti decays to
M H Lyda et al.
Human pathology, 31(8), 980-987 (2000-09-15)
The histologic classification of pulmonary neoplasms can have important implications regarding appropriate management of patients. Although the histologic classification of lung tumors is predominantly based on morphology, ancillary studies such as immunohistochemistry can be used in difficult cases, and the
Naoki Tarui et al.
Bioscience, biotechnology, and biochemistry, 66(2), 464-466 (2002-05-10)
Racemic indan derivatives have been resolved by the hydrolysis of amide bonds using Corynebacterium ammoniagenes IFO12612 to produce (S)-amine and (R)-amides. In the kinetic resolution of 1 (N-12-(6-methoxy-indan-1-yl)ethyl]acetamide), it was possible to run the reaction to 44% conversion on a
Haidong Tan et al.
Biotechnology letters, 27(16), 1177-1182 (2005-09-15)
Recombinant human interleukin-1 receptor antagonist (rHuIL-1ra) was produced in E. coli as an inclusion body. rHuIL-1ra was purified to Over 98% purity by anion exchange chromatography after on-column refolding. The optimized processes produced more than 2 g pure refolded rHuIL-1ra
Yajuan Wang et al.
AJR. American journal of roentgenology, 203(6), 1181-1191 (2014-11-22)
The purpose of this study was to investigate and validate adaptation of a cardiovascular CT angiography contrast injection protocol for lower tube potential. Eighty-three patients evaluated for thoracic aortic disease with a 256-MDCT scanner were imaged at 120 kV (group
Netta Nir et al.
Applied microbiology and biotechnology, 78(4), 659-667 (2008-01-23)
The asymmetric bio-reduction of 4-chloro-acetoacetic-acid-ethyl-ester to the pharmaceutical building block (S)-4-chloro-3-hydroxybutanoate-ethyl-ester requires the utilization of an enantioselective robust biocatalyst. Some of the natural Saccharomyces cerevisiae strains, isolated from Mount Carmel National Park in Israel, were characterized as resistant to environmental
Tami S McMullin et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(3), 492-501 (2006-12-26)
This study estimated the kinetic constants for oxidative metabolism of atrazine (ATRA) and its chlorotriazine (Cl-TRI) metabolites, 2-chloro-4-ethylamino-6-amino-1,3,5-triazine (ETHYL), 2-chloro-4-amino-6-isopropylamino-1,3,5-triazine (ISO), and diaminochlorotriazine (DACT), using freshly isolated rat hepatocytes. Hepatocytes were incubated with 1.74, 44, 98, and 266 microM ATRA.
C Lorentz et al.
Biotechnology letters, 32(12), 1955-1960 (2010-09-03)
Chlorogenic acid (5-caffeoyl quinic acid (CQA)) extracted from Hydrangea macrophylla (44%, w/w) with 98% purity, was acylated with palmitic acid by Novozym 435 to yield mono-acylated CQA. Acylation of CQA was achieved in 2-methyl-2-butanol at 60°C, and yielded two mono-acylated
Giancarlo Troncone et al.
Diagnostic cytopathology, 38(3), 172-176 (2009-08-21)
V600E BRAF mutation is emerging as an independent marker of papillary thyroid carcinoma aggressive behavior. Papillary thyroid carcinomas harboring this mutation should be extensively resected. However, this requires an unquestionable cytological diagnosis of malignancy. Thus, cytological specimens should be properly
Fiona V Cresswell et al.
The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)
Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid
Matthias Rief et al.
The international journal of cardiovascular imaging, 30(8), 1621-1627 (2014-08-15)
To evaluate computer-aided stenosis detection for computed tomography coronary angiography (CTA) in comparison with human reading and conventional coronary angiography (CCA) as the reference standard. 50 patients underwent CTA and CCA and out of these 44 were evaluable for computer-aided
Secil Berna Kuzu et al.
Biotechnology research international, 2012, 135498-135498 (2013-01-11)
This paper reports the isolation and identification of chitinase-producing Bacillus from chitin-containing wastes, production of a thermostable and alkaline chitinasese, and enzyme characterization. Bacillus thuringiensis subsp. kurstaki HBK-51 was isolated from soil and was identified. Chitinase was obtained from supernatant
Emiko Ando et al.
Public health nutrition, 1-11 (2020-08-05)
Recent research supports the importance of PUFA intake in children, particularly of EPA and DHA; however, few verified methods to assess whether PUFA intake is adequate are available. We assessed the correlation between serum PUFA and lipid concentrations with seafood
Steve Barrett et al.
International journal of sports physiology and performance, 9(6), 945-952 (2014-03-14)
The study aimed to establish the test-retest reliability and convergent validity of PlayerLoad™ (triaxial-accelerometer data) during a standardized bout of treadmill running. Forty-four team-sport players performed 2 standardized incremental treadmill running tests (7-16 km/h) 7 d apart. Players' oxygen uptake
J B Jacobson et al.
Acta obstetricia et gynecologica Scandinavica, 64(3), 241-244 (1985-01-01)
The continuously increasing incidence of vulvovaginal candidiasis necessitated a search for novel therapeutic modalities. Butoconazole nitrate (BN) a new imidazole, has been singled out for clinical studies since, in experimental vaginal candidiasis, it proved more effective than either miconazole nitrate
Maximilian G Posch et al.
International journal of cardiology, 145(1), 105-106 (2009-06-23)
A proper interaction between the endocardial-derived ligand Neuregulin-1 and the myocardial "Human Epidermal growth factor Receptor 2" (HER2) is essential for maintaining heart function. The shed extracellular domain (ECD) of HER2 circulates in blood and serves as a surrogate marker
Marlene C Nielsen et al.
Immunology, 159(1), 63-74 (2019-10-02)
Monocyte-derived macrophages (MDMs) generated from peripheral blood monocytes are widely used to model human macrophages for in vitro studies. However, the possible impact of different isolation methods on the resulting MDM phenotype is poorly described. We aimed to investigate the
Tony W Ho et al.
Headache, 51(1), 64-72 (2010-11-09)
To evaluate whether the same or different patients respond to triptans and telcagepant. Telcagepant is an oral calcitonin gene-related peptide receptor antagonist with acute antimigraine efficacy comparable to oral triptans. It is currently unknown whether migraine patients who cannot be
H Hahn et al.
The Journal of biological chemistry, 275(37), 28341-28344 (2000-07-08)
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children (Dagher, R., and Helman, L. (1999) Oncologist 4, 34-44), whereas medulloblastoma, a highly malignant tumor of the cerebellum, accounts for 20% of childhood brain tumors (Goodrich, L. V., and
Sandrine Gremlich et al.
Journal of reproductive immunology, 74(1-2), 143-151 (2007-03-21)
Poor embryo implantation can lead to poor feto-maternal exchanges and intrauterine growth restriction. Matrix metalloproteinase-2 (MMP-2) and MMP-9 are highly involved in early embryo implantation and three functional polymorphisms have been described for these genes: MMP2 C-1306T, MMP9 C-1562T and
Camilla Nielsen et al.
British journal of haematology, 160(1), 70-79 (2012-11-03)
The JAK2 V617F somatic mutation is present in the majority of patients with myeloproliferative cancer (polycythaemia vera, essential thrombocytosis, and primary myelofibrosis). However, the diagnostic value of the JAK2 V617F somatic mutation for myeloproliferative cancer in the general population is
Gladell P Paner et al.
The American journal of surgical pathology, 34(6), 792-799 (2010-04-28)
Accurate recognition of muscularis propria invasion by urothelial carcinoma is vital as it serves as a crossroad between conservative and aggressive clinical management. Recently, there has been attention to the hyperplastic pattern of muscularis mucosae which may mimic the muscularis
Juuso Rusanen et al.
Viruses, 13(2) (2021-01-28)
Accurate and rapid diagnostic tools are needed for management of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Antibody tests enable detection of individuals past the initial phase of infection and help examine vaccine responses. The major targets of human antibody
J P Chism et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(6), 651-657 (1985-11-01)
2-Nitrotoluene (2NT) induces DNA repair in the in vivo-in vitro hepatocyte unscheduled DNA synthesis assay in male, but not female, Fischer-344 rats. 3-Nitrotoluene (3NT) and 4-nitrotoluene (4NT) are inactive in both sexes. The structurally related rat hepatocarcinogen, 2,6-dinitrotoluene, which also
E F Hwang et al.
American journal of physiology. Renal physiology, 284(5), F1023-F1031 (2003-01-16)
We previously cloned Na(+)/Ca(2+) exchanger (NCX1) from mesangial cells of salt-sensitive (SNCX = NCX1.7) and salt-resistant (RNCX = NCX1.3) Dahl/Rapp rats. The abilities of these isoforms to regulate cytosolic Ca(2+) concentration ([Ca(2+)](i)) were assessed in fura 2-loaded OK cells expressing
Zuzana Gdovinová et al.
Cellular and molecular neurobiology, 26(7-8), 1219-1224 (2006-06-08)
1. The epsilon 4 allele of the apolipoprotein E gene increases the risk of late onset familial and sporadic Alzheimer disease. Relation of epsilon 4 allele of the apolipoprotein E gene to various types of dementia and the onset of
Linjie Zhang et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 31(2), 132-134 (2002-11-07)
To effectively screen p16 protein expression of different clinical stage nasopharyngeal carcinoma (NPC) by constructing and applying high-throughput tissue microarray/tissue chip. A series of tissue chips were prepared by using tissue arrayer with samples from different clinical stage NPC tumors
Vladimir M Moiseyenko et al.
Onkologie, 33(5), 231-238 (2010-05-27)
Several Asian studies demonstrated feasibility of front-line administration of gefitinib for the treatment of non-small cell lung carcinomas (NSCLCs) harboring intragenic epidermal growth factor receptor (EGFR) mutations. The experience of the use of this EGFR tyrosine kinase inhibitor (TKI) in
Dezhi Liu et al.
Neuroradiology, 56(12), 1023-1030 (2014-09-10)
We aim to investigate the correlation between presence of anterior temporal artery (ATA), the first major branch of middle cerebral artery (MCA), on conventional angiography and clinical outcome in patients with acute atherosclerotic M1-MCA occlusion. Consecutive patients with acute atherosclerotic
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