99-76-3

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Showing 1-30 of 54 results for "99-76-3" within Papers

PAX2 and PAX8 expression in primary and metastatic renal tumors: a comprehensive comparison.

Ayhan Ozcan et al.

Archives of pathology & laboratory medicine, 136(12), 1541-1551 (2012-12-01)

The diagnosis of renal cell carcinoma (RCC) remains problematic, especially in the context of metastasis or small-needle biopsies. PAX2 and PAX8 transcription factors are known to be expressed by several histologic types of renal neoplasms. To evaluate the diagnostic utility

Once-daily application of calcipotriene 0.005%-betamethasone dipropionate 0.064% ointment for repigmentation of facial vitiligo.

Marissa D Newman et al.

Cutis, 88(5), 256-259 (2012-01-26)

Vitiligo vulgaris is an autoimmune pigmentary disorder with no universally efficacious therapeutic options. Separate applications of calcipotriene ointment 0.005% and topical corticosteroid ointments have been successful in the repigmentation of vitiligo. We sought to examine the efficacy of a combination

Performance of a biotrickling filter in the removal of waste gases containing low concentrations of mixed VOCs from a paint and coating plant.

Jianjun Li et al.

Biodegradation, 23(1), 177-187 (2011-08-03)

The performance of a field-scale biotrickling filter (BTF) in the removal of waste gases containing low concentrations of mixed volatile organic compounds was evaluated. Results showed that acetone and methyl ethyl ketone (MEK) were more easily removed than toluene and

Efficacy of monthly tafenoquine for prophylaxis of Plasmodium vivax and multidrug-resistant P. falciparum malaria.

Douglas S Walsh et al.

The Journal of infectious diseases, 190(8), 1456-1463 (2004-09-21)

We assessed monthly doses of tafenoquine for preventing Plasmodium vivax and multidrug-resistant P. falciparum malaria. In a randomized, double-blind, placebo-controlled study, 205 Thai soldiers received either a loading dose of tafenoquine 400 mg (base) daily for 3 days, followed by

Review of tissue penetration and clinical efficacy of enoxacin in skin and skin structure infections and in osteomyelitis.

G A Pankey

Clinical pharmacokinetics, 16 Suppl 1, 46-51 (1989-01-01)

Enoxacin achieves a high penetration into skin tissue and blister fluid, reaching a maximum serum concentration (Cmax) of 3.7 mg/L at a time to reach maximum concentration (tmax) of 1.9 hours and a blister-fluid Cmax of 2.9 mg/L at a

A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice.

Rolando Pajon et al.

Vaccine, 33(11), 1317-1323 (2015-02-11)

The effect of protein-based meningococcal vaccines on prevention of nasopharyngeal colonization has been difficult to investigate experimentally because a reliable animal colonization model did not exist. Human CEACAM1 transgenic mice, which can be colonized by meningococci, were immunized IP with

Improved outcome of ventilator-associated pneumonia caused by methicillin-resistant Staphylococcus aureus in a trauma population.

Richard P Gonzalez et al.

American journal of surgery, 205(3), 255-258 (2013-02-05)

The treatment of ventilator-associated pneumonia (VAP) secondary to methicillin-resistant Staphylococcus aureus (MRSA) remains controversial. We performed a review of all blunt trauma patients diagnosed with MRSA VAP from June 2005 to June 2011. VAP for the first 3 years was

Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors.

Jérémie Doiron et al.

European journal of medicinal chemistry, 46(9), 4010-4024 (2011-06-28)

A series of bis- and mono-benzonitrile or phenyl analogues of letrozole 1, bearing (1,2,3 and 1,2,5)-triazole or imidazole, were synthesized and screened for their anti-aromatase activities. The unsubstituted 1,2,3-triazole 10a derivative displayed inhibitory activity comparable with that of the aromatase

Noncathartic CT colonography: Image quality assessment and performance and in a screening cohort.

Joel G Fletcher et al.

AJR. American journal of roentgenology, 201(4), 787-794 (2013-09-26)

Cathartic bowel preparation is a major barrier for colorectal cancer screening. We examined noncathartic CT colonography (CTC) quality and performance using four similar bowel-tagging regimens in an asymptomatic screening cohort. This prospective study included 564 asymptomatic subjects who underwent noncathartic

Frequency and genetic basis of MHC, beta-2-microglobulin and MEMO-1 loss of heterozygosity in sporadic breast cancer.

C R E McEvoy et al.

Tissue antigens, 60(3), 235-243 (2002-11-26)

The Human Leukocyte Antigen (HLA) class I molecules are critical factors in T cell recognition of abnormal, including neoplastic, cells. Loss of HLA class I expression phenotypes, as defined by immunohistochemistry-based tests, have been previously described in many types of

Increased Selectivity of Novozym 435 in the Asymmetric Hydrolysis of a Substrate with High Hydrophobicity Through the Use of Deep Eutectic Solvents and High Substrate Concentrations.

Yerko Fredes et al.

Molecules (Basel, Switzerland), 24(4) (2019-03-01)

The effects of the reaction medium and substrate concentration were studied on the selectivity of Novozym 435 using the asymmetric hydrolysis of dimethyl-3-phenylglutarate as a model reaction. Results show that the use of choline chloride ChCl:urea/phosphate buffer 50% (v/v) as

Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE.

T Yoshimura et al.

FEBS letters, 244(2), 487-493 (1989-02-27)

The purpose of this work was to analyze cDNA encoding human monocyte chemoattractant protein-1 (MCP-1), previously isolated from glioma cell line culture fluid. Screening of a cDNA library from total poly(A) RNA of glioma cell line U-105MG yielded a clone

Catheter radiofrequency ablation for arrhythmias under the guidance of the Carto 3 three-dimensional mapping system in an operating room without digital subtraction angiography.

Xingfu Huang et al.

Medicine, 97(25), e11044-e11044 (2018-06-21)

Several studies have reported the efficacy of a zero-fluoroscopy approach for catheter radiofrequency ablation of arrhythmias in a digital subtraction angiography (DSA) room. However, no reports are available on the ablation of arrhythmias in the absence of DSA in the

POM-ZP3, a bipartite transcript derived from human ZP3 and a POM121 homologue.

S Kipersztok et al.

Genomics, 25(2), 354-359 (1995-01-20)

Human POM-ZP3 is a novel bipartite RNA transcript that is derived from a gene homologous to rat POM121 (a nuclear pore membrane protein) and ZP3 (a sperm receptor ligand in the zona pellucida). The 5' region is 77% identical to

Design and validation of a metabolic disorder resequencing microarray (BRUM1).

Christopher K Bruce et al.

Human mutation, 31(7), 858-865 (2010-06-26)

The molecular genetic diagnosis of inherited metabolic disorders is challenging. The diseases are rare, and most show locus heterogeneity. Hence, testing of the genes associated with IMDs is time consuming and often not easily available. We report a resequencing array

Molecular cloning of the gene encoding the mouse parathyroid hormone/parathyroid hormone-related peptide receptor.

K A McCuaig et al.

Proceedings of the National Academy of Sciences of the United States of America, 91(11), 5051-5055 (1994-05-24)

The parathyroid hormone/parathyroid hormone-related peptide receptor (PTHR) is a G-protein-coupled receptor containing seven predicted transmembrane domains. We have isolated and characterized recombinant bacteriophage lambda EMBL3 genomic clones containing the mouse PTHR gene, including 10 kilobases of the promoter region. The

Reducing the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis using 4-Fr pancreatic plastic stents placed with common-type guidewires: Results from a prospective multinational registry.

Nadav Sahar et al.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31(3), 299-306 (2018-12-07)

Pancreatic plastic stents (PPS) can reduce the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Prospective multicenter documentation of PEP rate after PPS placement is scarce. A new 4-Fr stent designed to be deployed over a 0.035-inch guidewire was used to

Tissue-specific dynamic codon redefinition in Drosophila.

Andrew M Hudson et al.

Proceedings of the National Academy of Sciences of the United States of America, 118(5) (2021-01-28)

Translational stop codon readthrough occurs in organisms ranging from viruses to mammals and is especially prevalent in decoding Drosophila and viral mRNAs. Recoding of UGA, UAG, or UAA to specify an amino acid allows a proportion of the protein encoded

Surveillance of Enterococcus spp. reveals distinct species and antimicrobial resistance diversity across a One-Health continuum.

Rahat Zaheer et al.

Scientific reports, 10(1), 3937-3937 (2020-03-05)

For a One-Health investigation of antimicrobial resistance (AMR) in Enterococcus spp., isolates from humans and beef cattle along with abattoirs, manured fields, natural streams, and wastewater from both urban and cattle feedlot sources were collected over two years. Species identification

Long term molecular responses in a cohort of Danish patients with essential thrombocythemia, polycythemia vera and myelofibrosis treated with recombinant interferon alpha.

Thomas Stauffer Larsen et al.

Leukemia research, 37(9), 1041-1045 (2013-07-06)

Within recent years data has accumulated demonstrating the efficacy of recombinant interferon alpha2 (rIFN-alpha2) in the treatment of chronic myeloproliferative neoplasms (MPNs). We report on clinical and molecular data in the largest cohort of JAK2 V617F mutant MPN Danish patients

Regadenoson dynamic computed tomography myocardial perfusion using low-dose protocol for evaluation of the ischemic burden. ULYSSES study.

Anna Oleksiak et al.

Journal of cardiovascular computed tomography, 14(5), 428-436 (2020-02-08)

The purpose of this study was to assess the feasibility of low-dose dynamic regadenoson computed tomography perfusion (CTP) protocol, and to determine which parameters provide the best diagnostic yield for the presence and burden of ischemia in reference to the

Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy.

Noriaki Sunaga et al.

Lung cancer (Amsterdam, Netherlands), 56(3), 383-389 (2007-03-21)

Mutations in the epidermal growth factor receptor (EGFR) gene are associated with increased sensitivity of non-small cell lung cancer (NSCLC) to gefitinib, an EGFR tyrosine kinase inhibitor. The objective of this study was to prospectively evaluate the efficacy of gefitinib

Synergistic protective effect of folic acid and vitamin B12 against nicotine-induced oxidative stress and apoptosis in pancreatic islets of the rat.

Ankita Bhattacharjee et al.

Pharmaceutical biology, 54(3), 433-444 (2015-05-15)

Nicotine is an abundant and most significant component of cigarette smoke. Epidemiological evidence strongly suggests an association between cigarette smoking and pancreatic injury, although effects of smoking on endocrine pancreas are still controversial. We examined the impact and underlying mechanisms

Evaluation of the health aspects of methyl paraben: a review of the published literature.

M G Soni et al.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1335-1373 (2002-10-22)

Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through

Hyperbaric articaine with or without fentanyl in spinal anaesthesia: patient and observer blinded comparison.

P Kairaluoma et al.

Acta anaesthesiologica Scandinavica, 57(1), 118-125 (2012-10-19)

The rapid and short-acting local anaesthetic articaine is a feasible spinal anaesthetic for day-case open inguinal herniorrhaphy (OIH). We hypothesised that similarly to other spinal local anaesthetics, the addition of fentanyl may prolong articaine spinal analgesia without prolonging motor block.

Genetically modified strains of Ralstonia eutropha H16 with β-ketothiolase gene deletions for production of copolyesters with defined 3-hydroxyvaleric acid contents.

Nicole Lindenkamp et al.

Applied and environmental microbiology, 78(15), 5375-5383 (2012-05-29)

β-Ketothiolases catalyze the first step of poly(3-hydroxybutyrate) [poly(3HB)] biosynthesis in bacteria by condensation of two acetyl coenzyme A (acetyl-CoA) molecules to acetoacetyl-CoA and also take part in the degradation of fatty acids. During growth on propionate or valerate, Ralstonia eutropha

Physiological role of macrophage inflammatory protein-3 alpha induction during maturation of intestinal macrophages.

Martin Hausmann et al.

Journal of immunology (Baltimore, Md. : 1950), 175(3), 1389-1398 (2005-07-22)

Intestinal macrophages (IMAC) are a central component in the defense of the intestinal mucosa against luminal microbes. In normal mucosa, monocytes differentiate to immunologically tolerant IMAC with a typical phenotype lacking activation markers such as CD14 and TLRs 2 and

Hexokinase III, cyclin A and galectin-3 are overexpressed in malignant follicular thyroid nodules.

L Hooft et al.

Clinical endocrinology, 68(2), 252-257 (2007-09-18)

Distinguishing malignant thyroid nodules in patients with follicular cytology by fine-needle aspiration (FNA) remains problematic. The large majority of thyroid nodules (> 85%) are overtreated. Therefore, a clear need exists to develop more accurate initial diagnostic tests for follicular thyroid

Survival results in biphasic malignant pleural mesothelioma patients: A multicentric analysis.

Filippo Lococo et al.

The Journal of thoracic and cardiovascular surgery, 159(4), 1584-1593 (2019-10-09)

The best strategy of care for biphasic malignant pleural mesothelioma (Biph-MPM) is controversial. In this study, a large dataset of Biph-MPM cases was reviewed to identify prognostic factors and to evaluate the role of a multimodal approach, including cancer-directed surgery.

[Correlation between expression of excision repair cross-complementing 1 and cisplatin sensitivity in non-small cell lung cancer].

Xing-peng Han et al.

Zhonghua yi xue za zhi, 90(30), 2115-2118 (2010-10-30)

To investigate the correlation between excision repair cross-complementing 1 (ERCC1) expression and cisplatin sensitivity in non-small cell lung cancer (NSCLC). A total of 168 NSCLC patients were selected from our hospital from January 2005 to December 2007. The expression of

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