A1346

Applied Filters:

Keyword:'A1346'

Showing 1-13 of 13 results for "A1346" within Papers

Francisella t ularensis Proteome: Low Levels of ASB-14 Facilitate the Visualization of Membrane Proteins in Total Protein Extracts

Twine SM, et al.

Journal of Proteome Research, 4(5), 1848-1854 (2005)

Antitumor activity of CTFB, a novel anticancer agent, is associated with the down-regulation of nuclear factor-kappaB expression and proteasome activation in head and neck squamous carcinoma cell lines.

Sergej Skvortsov et al.

Molecular cancer therapeutics, 6(6), 1898-1908 (2007-06-19)

This study aimed to characterize the antitumor activity of 5-Chloro-N-[2-[2-(4-chloro-phenyl)-3-methyl-butoxy]-5-trifluoromethyl-phenyl]-2-hydroxy-benzamide (CTFB), a novel anticancer agent, in head and neck cancer cell lines, FaDu, SCC-25 and cisplatin-resistant CAL-27. CTFB was generated as a result of an extensive medicinal chemistry effort on

Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation.

Manabu Minami et al.

The Journal of biological chemistry, 283(15), 9692-9703 (2008-02-14)

Macrophage activation participates pivotally in the pathophysiology of chronic inflammatory diseases, including atherosclerosis. Through the receptor EP4, prostaglandin E(2) (PGE(2)) exerts an anti-inflammatory action in macrophages, suppressing stimulus-induced expression of certain proinflammatory genes, including chemokines. We recently identified a novel

Protein Sample Preparation for Proteomic Analysis in Leishmania donovani

Alexandros A and Despina S

Bio-protocol, 4(5), 70-75 (2014)

Advances in protein solubilisation for two-dimensional electrophoresis.

B Herbert

Electrophoresis, 20(4-5), 660-663 (1999-05-27)

Two-dimensional (2-D) electrophoresis remains the highest resolution technique for protein separation and is the method of choice when complex samples need to be arrayed for characterisation, as in proteomics. However, in current proteome projects the total number of proteins identified

Stepwise solubilization-based antigen removal for xenogeneic scaffold generation in tissue engineering.

Maelene L Wong et al.

Acta biomaterialia, 9(5), 6492-6501 (2013-01-17)

The ability of residual antigens on decellularized tissue to elicit the immune response upon implantation motivates development of a more rigorous antigen removal (AR) process for xenogeneic scaffold generation. Antigen removal strategies promoting solubilization of hydrophilic proteins (predominantly cytoplasmic) enhance

Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa.

Nityakalyani Srinivas et al.

Science (New York, N.Y.), 327(5968), 1010-1013 (2010-02-20)

Antibiotics with new mechanisms of action are urgently required to combat the growing health threat posed by resistant pathogenic microorganisms. We synthesized a family of peptidomimetic antibiotics based on the antimicrobial peptide protegrin I. Several rounds of optimization gave a

Solubilisation of the armadillo-repeat protein β-catenin using a zwitterionic detergent allows resolution of phosphorylated forms by 2DE.

Meredith J Layton et al.

Electrophoresis, 33(12), 1804-1813 (2012-06-29)

β-catenin is a member of the armadillo repeat family of proteins and has important functions in cell-cell adhesion and Wnt signalling. Different protein species of β-catenin have been shown to exist in the cell and the relative proportions of these

Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs.

Xi Xie et al.

Marine drugs, 16(4) (2018-04-06)

Oxidative stress is the main cause of diabetic nephropathy (DN) progression. Nuclear factor-erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE) signaling is a crucial cellular defense system to cope with oxidative stress. Astaxanthin (AST) is a fat-soluble xanthophyll carotenoid with

The use of ASB-14 in combination with CHAPS is the best for solubilization of human brain proteins for two-dimensional gel electrophoresis.

Daniel Martins-de-Souza et al.

Briefings in functional genomics & proteomics, 6(1), 70-75 (2007-06-09)

Protein extraction is the most important step to reveal a proteome by Two-Dimensional Gel Electrophoresis. Usually, the urea/thiourea based standard protein extraction buffer (SB) is combined with detergents with the aim of achieving better resolution and solubilization of different classes

Thermodynamic and structural characterization of zwitterionic micelles of the membrane protein solubilizing amidosulfobetaine surfactants ASB-14 and ASB-16

D Andrea MG, et al.

Langmuir, 27(13), 8248-8256 (2011)

Two-dimensional electrophoresis and peptide mass fingerprinting of bacterial outer membrane proteins.

M P Molloy et al.

Electrophoresis, 22(9), 1686-1696 (2001-06-27)

Many bacterial outer membrane proteins (OMPs) are missing from two-dimensional (2-D) gel proteome maps. Recently, we developed a technique for 2-D electrophoresis (2-DE) of Escherichia coli OMPs using alkaline pH incubation for isolation of OMPs, followed by improved solubilization conditions

Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells.

Zhiquan Chen et al.

Free radical biology & medicine, 102, 77-86 (2016-11-15)

Nrf2/ARE signaling pathway is a crucial cellular defense system to cope with oxidative stress, which is adaptively activated, in diabetic condition that is not efficient enough to resist the oxidative stress provoked by hyperglycemia. We have previously demonstrated that Connexin43

Page 1 of 1