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Showing 1-30 of 233 results for "A4034" within Papers
Eugenio Jose Garcia et al.
The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 7(2), 154-162 (2012-05-31)
It is generally not recommended that bonded restoration treatment should be carried out immediately after bleaching treatment. However, the use of antioxidants such as sodium ascorbate can be useful to avoid a waiting period. This article is a brief review
J Bautista-Ortega et al.
Poultry science, 93(4), 979-988 (2014-04-08)
The effects of l-Arg, vitamin C (VC), and vitamin E (VE) on xanthine- (XO) and NAD(P)H-oxidase (NOX) activities, and nitric oxide (NO) availability of hypoxic broilers were evaluated. Chickens were kept in wire cages with free access to feed and
Hiroyuki Katayama et al.
Cell, 181(5), 1176-1187 (2020-05-22)
Dysfunctional mitochondria accumulate in many human diseases. Accordingly, mitophagy, which removes these mitochondria through lysosomal degradation, is attracting broad attention. Due to uncertainties in the operational principles of conventional mitophagy probes, however, the specificity and quantitativeness of their readouts are
Xi Su et al.
Journal of experimental & clinical cancer research : CR, 40(1), 34-34 (2021-01-21)
BRAFV600E mutation is the most common mutation in thyroid cancer. It strongly activates MAPK/ERK pathway and indicates an invasive subtype of thyroid cancer. PLX4032 is a selective oral inhibitor of the BRAFV600 kinase although with limited effect in treating this
Feng Xu et al.
Journal of nanoscience and nanotechnology, 13(1), 558-563 (2013-05-08)
In this article, we describe an aptamer-based sandwich-type electrochemical sensor for the detection of human alpha-thrombin. Au nanoneedles were synthesized in the hole of the naked polycarbonate (PC) template using electrodepositing strategy. The thiolated thrombin aptamer I was immobilized as
[Not too eager prescribing vitamin C for the common cold!].
N Senn
Revue medicale suisse, 9(401), 1854-1855 (2013-11-07)
Xu Qian et al.
Molecular cell, 76(6), 885-895 (2019-10-21)
Hypoxia, which occurs during tumor growth, triggers complex adaptive responses in which peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) plays a critical role in mitochondrial biogenesis and oxidative metabolism. However, how PGC-1α is regulated in response to oxygen availability remains
Kristina A Simeone et al.
Experimental neurology, 251, 84-90 (2013-11-26)
Mitochondria actively participate in neurotransmission by providing energy (ATP) and maintaining normative concentrations of reactive oxygen species (ROS) in both presynaptic and postsynaptic elements. In human and animal epilepsies, ATP-producing respiratory rates driven by mitochondrial respiratory complex (MRC) I are
FPIN's clinical inquiries. Treatments for symptoms of the common cold.
Cat Livingston et al.
American family physician, 88(12), Online-Online (2013-12-25)
Max Leenders et al.
International journal of cancer, 135(12), 2930-2939 (2014-04-29)
Carotenoids and vitamins A, C and E are possibly associated with a reduced colorectal cancer (CRC) risk through antioxidative properties. The association of prediagnostic plasma concentrations and dietary consumption of carotenoids and vitamins A, C and E with the risk
Jasper M A de Jong et al.
Adipocyte, 7(3), 166-179 (2018-06-19)
Much current understanding of brown adipocyte development comes from in-vitro cell models. Serum type may affect the behavior of cultured cells and thus conclusions drawn. Here, we investigate effects of serum type ("fetal bovine" versus "newborn calf") on responses to
Qi Xing et al.
Journal of biomedical materials research. Part A, 103(12), 3807-3814 (2015-06-16)
During tissue injury and wound healing process, there are dynamic reciprocal interactions among cells, extracellular matrix (ECM), and mediating molecules which are crucial for functional tissue repair. Nitric oxide (NO) is one of the key mediating molecules that can positively
Usama Ahmed Ali et al.
The Cochrane database of systematic reviews, 8(8), CD008945-CD008945 (2014-08-22)
Reduced intake and absorption of antioxidants due to pain and malabsorption are probable causes of the lower levels of antioxidants observed in patients with chronic pancreatitis (CP). Improving the status of antioxidants might be effective in slowing the disease process
Martin Sillesen et al.
The journal of trauma and acute care surgery, 76(1), 12-19 (2013-12-26)
Traumatic brain injury (TBI) and hemorrhagic shock (HS) can be associated with coagulopathy and inflammation, but the mechanisms are poorly understood. We hypothesized that a combination of TBI and HS would disturb coagulation, damage the endothelium, and activate inflammatory and
Francisco J Garcia et al.
European journal of medicinal chemistry, 88, 28-33 (2014-06-30)
Reversible oxidation of protein tyrosine phosphatases (PTPs) has emerged as an important regulatory mechanism whereby reactive oxygen species (ROS) inactivates the PTP and promotes phosphorylation and induction of the signaling cascade. The lack of sensitive and robust methods to directly
Tim J Wigle et al.
Journal of biomolecular screening, 20(6), 810-820 (2015-03-11)
Demethylation of histones by lysine demethylases (KDMs) plays a critical role in controlling gene transcription. Aberrant demethylation may play a causal role in diseases such as cancer. Despite the biological significance of these enzymes, there are limited assay technologies for
A L Althaus et al.
Journal of neurophysiology, 113(4), 1184-1194 (2014-11-28)
Hilar ectopic dentate granule cells (DGCs) are a salient feature of aberrant plasticity in human temporal lobe epilepsy (TLE) and most rodent models of the disease. Recent evidence from rodent TLE models suggests that hilar ectopic DGCs contribute to hyperexcitability
Yan Zhu et al.
Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 19(4), 291-303 (2013-06-05)
Patulin is a mycotoxin produced by a wide range of molds involved in fruit spoilage, most commonly by Penicillium expansum and is a health concern for both consumers and manufacturers. The current study evaluated feasibility of monochromatic ultraviolet (UV) radiation
M Zen Rahfiludin et al.
The Southeast Asian journal of tropical medicine and public health, 44(5), 733-739 (2014-01-21)
Plasmodium vivax infection in humans can relapse and is associated with iron deficiency. The immune response plays an important role in preventing relapse. In this study we analyzed the effect of zinc and vitamin C supplementation on hemoglobin and hematocrit
The alteration of components in the fermented Hwangryunhaedok-tang and its neuroprotective activity.
Hye Jin Yang et al.
Pharmacognosy magazine, 7(27), 207-212 (2011-10-05)
Hwangryunhaedok-tang is a traditional herbal prescription that has sedative activity, hypotensive and anti-bacterial effects. In this study, we investigated the alteration of contents of components in Hwangryunhaedok-tang, antioxidant activity and neuroprotective activity by fermentation with Lactobacillus acidophilus KFRI 128. Contents
Melissa A Erlandson et al.
PloS one, 10(7), e0132008-e0132008 (2015-07-03)
The organization of cortical networks can be investigated functionally in brain slices. Laser scanning photostimulation (LSPS) with glutamate-uncaging allows for a rapid survey of all connections impinging on single cells recorded in patch-clamp. We sought to develop a variant of
Claire M White et al.
The Cochrane database of systematic reviews, 12(12), CD008146-CD008146 (2014-12-19)
Persistent feelings of fatigue (or subjective fatigue), which may be experienced in the absence of physiological factors, affect many people with peripheral neuropathy. A variety of interventions for subjective fatigue are available, but little is known about their efficacy or
Adam Drewnowski et al.
The American journal of clinical nutrition, 99(5 Suppl), 1223S-1228S (2014-03-22)
Nutrient profiling is the technique of rating or classifying foods on the basis of their nutritional value. Foods that supply relatively more nutrients than calories are defined as nutrient dense. Nutrient profile models calculate the content of key nutrients per
Bryan M Hooks et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(10), 4418-4426 (2015-03-13)
Cortical cells integrate synaptic input from multiple sources, but how these different inputs are distributed across individual neurons is largely unknown. Differences in input might account for diverse responses in neighboring neurons during behavior. We present a strategy for comparing
Christopher M Stephenson et al.
Cancer chemotherapy and pharmacology, 72(1), 139-146 (2013-05-15)
This phase I clinical trial evaluated the safety, tolerability, and pharmacokinetics of high-dose intravenous (i.v.) ascorbic acid as a monotherapy in patients with advanced solid tumors refractory to standard therapy. Five cohorts of three patients received i.v. ascorbic acid administered
Sławomir Tokarski et al.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 35(207), 136-140 (2013-11-15)
One of the main after-effects of chemotherapy used in cancer treatment is an augmented production of reactive oxygen species (ROS). In turn ROS become a source of unwanted side effects of chemotherapy, often forcing the discontinuation of the therapy. Ascorbic
Olivier Fain
La Revue du praticien, 63(8), 1091-1096 (2013-12-05)
Vitamin C is a water soluble vitamin which is mainly fresh fruits and vegetables foodborne. Vitamin C deficiency is most often due to a lack of daily amount. Scurvy is characterized by the occurrence of fatigue, myalgia, arthralgia, purpura, bleeding
Billel Benmimoun et al.
Nature communications, 11(1), 6106-6106 (2020-12-02)
Pathogens able to cross the blood-brain barrier (BBB) induce long-term neurological sequelae and death. Understanding how neurotropic pathogens bypass this strong physiological barrier is a prerequisite to devise therapeutic strategies. Here we propose an innovative model of infection in the
Xuan Ming et al.
Cell research, 30(11), 980-996 (2020-06-26)
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question. A replication-coupled DNA methylation maintenance model was
Sevnur Serim et al.
Organic & biomolecular chemistry, 13(8), 2293-2299 (2015-01-03)
Activity-based probes (ABPs) are powerful tools for the analysis of active enzyme species in whole proteomes, cells or animals. Quenched fluorescent ABPs (qABPs) can be applied for real time imaging, allowing the visualization of dynamic enzyme activation by fluorescent microscopy.
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