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Showing 1-30 of 1660 results for "A6283" within Papers

Improvement of sugar analysis sensitivity using anion-exchange chromatography-electrospray ionization mass spectrometry with sheath liquid interface.

Xian-Bing Xu et al.

Journal of chromatography. A, 1366, 65-72 (2014-09-24)

A novel interface that enables high-performance anion-exchange chromatography (HPAEC) to be coupled with electrospray ionization (ESI) mass spectrometry (MS) is reported. A sheath liquid consisting of 50mM NH4Ac in isopropanol with 0.05% acetic acid, infused at a flow rate of

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.

Galbha Duggal et al.

Stem cells and development, 22(23), 3141-3155 (2013-07-09)

Human embryonic stem cells (hESCs) are more similar to "primed" mouse epiblast stem cells (mEpiSCs). mEpiSCs, which are derived in Activin A, show an increased propensity to form primordial germ cell (PGC)-like cells in response to bone morphogenic protein 4

Comparison between ATR-IR, Raman, concatenated ATR-IR and Raman spectroscopy for the determination of total antioxidant capacity and total phenolic content of Chinese rice wine.

Zhengzong Wu et al.

Food chemistry, 194, 671-679 (2015-10-17)

The application of attenuated total reflectance infrared spectroscopy (ATR-IR), Raman spectroscopy (RS) and combination of ATR-IR and RS for measurements of total antioxidant capacity (TAC) and total phenolic content (TPC) of Chinese rice wine (CRW) were investigated in this study.

Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence.

Ruben D Arroyo-Olarte et al.

PLoS biology, 13(11), e1002288-e1002288 (2015-11-14)

The major membrane phospholipid classes, described thus far, include phosphatidylcholine (PtdCho), phosphatidylethanolamine (PtdEtn), phosphatidylserine (PtdSer), and phosphatidylinositol (PtdIns). Here, we demonstrate the natural occurrence and genetic origin of an exclusive and rather abundant lipid, phosphatidylthreonine (PtdThr), in a common eukaryotic

Apple derived cellulose scaffolds for 3D mammalian cell culture.

Daniel J Modulevsky et al.

PloS one, 9(5), e97835-e97835 (2014-05-21)

There are numerous approaches for producing natural and synthetic 3D scaffolds that support the proliferation of mammalian cells. 3D scaffolds better represent the natural cellular microenvironment and have many potential applications in vitro and in vivo. Here, we demonstrate that

Chick embryo xenograft model reveals a novel perineural niche for human adipose-derived stromal cells.

Ingrid R Cordeiro et al.

Biology open, 4(9), 1180-1193 (2015-09-01)

Human adipose-derived stromal cells (hADSC) are a heterogeneous cell population that contains adult multipotent stem cells. Although it is well established that hADSC have skeletal potential in vivo in adult organisms, in vitro assays suggest further differentiation capacity, such as

Characterization of antibiotic and disinfectant susceptibility profiles among Pseudomonas aeruginosa veterinary isolates recovered during 1994-2003.

R C Beier et al.

Journal of applied microbiology, 118(2), 326-342 (2014-11-29)

To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants. Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from sixteen states during 1994-2003 were tested for susceptibility. Most isolates were resistant

Cordycepin prevents oxidative stress-induced inhibition of osteogenesis.

Feng Wang et al.

Oncotarget, 6(34), 35496-35508 (2015-10-16)

Oxidative stress is known to be involved in impairment of osteogenesis and age-related osteoporosis. Cordycepin is one of the major bioactive components of Cordyceps militaris that has been shown to exert antioxidant and anti-inflammatory activities. However, there are few reports

Separation of isomeric short-chain acyl-CoAs in plant matrices using ultra-performance liquid chromatography coupled with tandem mass spectrometry.

Randy W Purves et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 1-7 (2015-01-02)

Acyl coenzyme A (acyl-CoA) thioesters are important intermediates in cellular metabolism and being able to distinguish among them is critical to fully understanding metabolic pathways in plants. Although significant advances have been made in the identification and quantification of acyl-CoAs

Evaluation of 4-substituted styrenes as functional monomers for the synthesis of theophylline-specific molecularly imprinted polymers.

Hazit Zayas et al.

Organic & biomolecular chemistry, 12(36), 6994-7003 (2014-06-17)

Six novel functional monomers: 4-(4-vinylphenyl)pyridine (M1), 4′-vinylbiphenyl-4-ol (M2), N,N-dimethyl-4′-vinylbiphenyl-3-amine (M3), (4′-vinylbiphenyl-4-yl)methanol (M4), 4′-vinylbiphenyl-4-carboxylic acid (M5) and 4-hydroxy-5-methyl-4′-vinylbiphenyl-3-carboxylic acid (M6), were examined for their ability to imprint theophylline (1). Using a molecular modelling-NMR titration approach, M2 and M6 were predicted to

Development of surface plasmon resonance imaging biosensors for detection of ubiquitin carboxyl-terminal hydrolase L1.

Anna Sankiewicz et al.

Analytical biochemistry, 469, 4-11 (2014-10-15)

We have developed a new method for highly selective determination of the ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) concentration using a surface plasmon resonance imaging (SPRI) technique and two different biosensors. UCH-L1 was captured from a solution by immobilized specific rabbit

Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cells.

John O Suberu et al.

ChemMedChem, 9(12), 2791-2797 (2014-09-12)

In parts of Africa and Asia, self-medication with a hot water infusion of Artemisia annua (Artemisia tea) is a common practice for a number of ailments including malaria and cancer. In our earlier work, such an extract showed better potency

Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia.

Margret I Moré et al.

Advances in therapy, 31(12), 1247-1262 (2014-11-22)

We report previously unpublished, early pilot studies performed with a brain-health food supplement containing a proprietary blend of 100 mg phosphatidylserine (PS) and 80 mg phosphatidic acid (PA) produced from soy lecithin. Serum analysis after single PS+PA ingestion was performed in healthy

Kafirin Nanoparticle-Stabilized Pickering Emulsions as Oral Delivery Vehicles: Physicochemical Stability and in Vitro Digestion Profile.

Jie Xiao et al.

Journal of agricultural and food chemistry, 63(47), 10263-10270 (2015-11-06)

Kafirin nanoparticle-stabilized Pickering emulsions (KPEs) were used to encapsulate curcumin. The stability of KPEs under processing conditions and their protective effects against photo-oxidation of curcumin and lipid oxidation of oil in emulsions, as well as the digestion profiles in gastrointestinal

Global gene expression profiling in R155H knock-in murine model of VCP disease.

Angèle Nalbandian et al.

Clinical and translational science, 8(1), 8-16 (2014-11-13)

Dominant mutations in the valosin-containing protein (VCP) gene cause inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia, which is characterized by progressive muscle weakness, dysfunction in bone remodeling, and frontotemporal dementia. More recently, VCP has been

Endometrial apical glycoproteomic analysis reveals roles for cadherin 6, desmoglein-2 and plexin b2 in epithelial integrity.

H Singh et al.

Molecular human reproduction, 21(1), 81-94 (2014-09-23)

Implantation failure is one of the major causes of infertility and remains a major barrier to assisted reproduction success. Initial receptivity to implantation is regulated by the endometrial luminal epithelium under maternal hormonal control. Identification of epithelial cell surface components

Preparation and study of tramadol imprinted micro-and nanoparticles by precipitation polymerization: microwave irradiation and conventional heating method.

Mahmoud Seifi et al.

International journal of pharmaceutics, 471(1-2), 37-44 (2014-05-06)

In the present work a series of tramadole imprinted micro- and nanoparticles were prepared and study their recognition properties. Methacrylic acid (MAA), as a functional monomer, ethylene glycol dimethacrylate (EGDMA) as a cross-linker and different solvents (chloroform, toluene and acetonitrile

New insights into the human brain proteome: Protein expression profiling of deep brain stimulation target areas.

Joaquín Fernández-Irigoyen et al.

Journal of proteomics, 127(Pt B), 395-405 (2015-04-08)

Deep brain stimulation (DBS) is a neurosurgical procedure that provides therapeutic benefits for movement and affective disorders. The nucleus basalis of Meynert (NBM) and substantia nigra (SN) are considered target areas to apply DBS. Even though the degeneration of NBM

A unique capsular polysaccharide structure from the psychrophilic marine bacterium Colwellia psychrerythraea 34H that mimics antifreeze (glyco)proteins.

Sara Carillo et al.

Journal of the American Chemical Society, 137(1), 179-189 (2014-12-20)

The low temperatures of polar regions and high-altitude environments, especially icy habitats, present challenges for many microorganisms. Their ability to live under subfreezing conditions implies the production of compounds conferring cryotolerance. Colwellia psychrerythraea 34H, a γ-proteobacterium isolated from subzero Arctic

Direct enantioseparation of underivatized aliphatic 3-hydroxyalkanoic acids with a quinine-based zwitterionic chiral stationary phase.

Federica Ianni et al.

Journal of chromatography. A, 1363, 101-108 (2014-04-15)

While aliphatic 2-hydroxyalkanoic acids have been more or less successfully enantioseparated with various chiral stationary phases by HPLC and GC, analogous applications on underivatized aliphatic 3-hydroxyalkanoic acids are completely absent in the scientific literature. With the aim of closing this

Adhesion of perfume-filled microcapsules to model fabric surfaces.

Yanping He et al.

Journal of microencapsulation, 31(5), 430-439 (2014-04-05)

The retention and adhesion of melamine formaldehyde (MF) microcapsules on a model fabric surface in aqueous solution were investigated using a customised flow chamber technique and atomic force microscopy (AFM). A cellulose film was employed as a model fabric surface.

Photocatalysis of sub-ppm limonene over multiwalled carbon nanotubes/titania composite nanofiber under visible-light irradiation.

Wan-Kuen Jo et al.

Journal of hazardous materials, 283, 680-688 (2014-12-03)

This study was conducted under visible-light exposure to investigate the photocatalytic characteristics of a multiwalled carbon nanotube/titania (TiO2) composite nanofiber (MTCN) using a continuous-flow tubular reactor. The MTCN was prepared by a sol-gel process, followed by an electrospinning technique. The

Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model.

Suresh B Lakshminarayana et al.

Antimicrobial agents and chemotherapy, 59(2), 1200-1210 (2014-12-10)

Limited information is available on the pharmacokinetic (PK) and pharmacodynamic (PD) parameters driving the efficacy of antimalarial drugs. Our objective in this study was to determine dose-response relationships of a panel of related spiroindolone analogs and identify the PK-PD index

Drug loaded homogeneous electrospun PCL/gelatin hybrid nanofiber structures for anti-infective tissue regeneration membranes.

Jiajia Xue et al.

Biomaterials, 35(34), 9395-9405 (2014-08-20)

Infection is the major reason for guided tissue regeneration/guided bone regeneration (GTR/GBR) membrane failure in clinical application. In this work, we developed GTR/GBR membranes with localized drug delivery function to prevent infection by electrospinning of poly(ε-caprolactone) (PCL) and gelatin blended

Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30.

Julie Carnesecchi et al.

PloS one, 10(3), e0120672-e0120672 (2015-03-18)

The post-menopausal decrease in estrogen circulating levels results in rapid skin deterioration pointing out to a protective effect exerted by these hormones. The identity of the skin cell type responding to estrogens is unclear as are the cellular and molecular

TiO2 immobilized on Manihot carbon: optimal preparation and evaluation of its activity in the decomposition of indigo carmine.

Cynthia M Antonio-Cisneros et al.

International journal of molecular sciences, 16(1), 1590-1612 (2015-01-15)

Applications of carbon-TiO2 materials have attracted attention in nanotechnology due to their synergic effects. We report the immobilization of TiO2 on carbon prepared from residues of the plant Manihot, commercial TiO2 and glycerol. The objective was to obtain a moderate

Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation.

Aránzazu Mediero et al.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(5), 837-854 (2014-12-09)

Bone metabolism is a vital process that involves resorption by osteoclasts and formation by osteoblasts, which is closely regulated by immune cells. The neuronal guidance protein Netrin-1 regulates immune cell migration and inflammatory reactions, but its role in bone metabolism

Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.

Pengfei Xu et al.

Molecular and cellular endocrinology, 406, 87-101 (2015-03-01)

White adipose tissue has now been recognized as an important endocrine organ secreting bioactive molecules termed adipocytokines. In obesity, anti-inflammatory adipocytokines like adiponectin are decreased while pro-inflammatory factors are over-produced. These changes contribute to the development of insulin resistance and

Menstrual blood-derived stromal stem cells from women with and without endometriosis reveal different phenotypic and functional characteristics.

Shohreh Nikoo et al.

Molecular human reproduction, 20(9), 905-918 (2014-06-19)

Retrograde flow of menstrual blood cells during menstruation is considered as the dominant theory for the development of endometriosis. Moreover, current evidence suggests that endometrial-derived stem cells are key players in the pathogenesis of endometriosis. In particular, endometrial stromal stem

IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells.

Tia Y Brodeur et al.

Journal of immunology (Baltimore, Md. : 1950), 195(11), 5251-5260 (2015-11-01)

Type 2 effector production of IL-13, a demonstrated requirement in models of fibrosis, is routinely ascribed to CD4(+) Th2 cells. We now demonstrate a major role for CD8(+) T cells in a murine model of sterile lung injury. These pulmonary

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