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Showing 61-68 of 68 results for "a6419" within Papers
Jingbo Jiang et al.
Journal of the American Heart Association, 8(16), e012385-e012385 (2019-08-20)
Background α Carboxyl terminus 1 (αCT1) is a 25-amino acid therapeutic peptide incorporating the zonula occludens-1 (ZO-1)-binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on chronic wounds. In mice, we reported that αCT1 reduced
Monika Bambouskova et al.
Cell reports, 34(10), 108756-108756 (2021-03-11)
Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activated macrophages. We show that endogenous itaconate is
Changliang He et al.
International immunopharmacology, 71, 328-335 (2019-04-06)
Pyroptosis is a different type of proinflammatory and lytic mode of cell death from apoptosis and necrosis, which play a killer and cleaner to the pathogenic microorganisms as an immune response when the host is infected by pathogenic microorganisms. Ketone
Nora Grahl et al.
PLoS pathogens, 11(8), e1005133-e1005133 (2015-09-01)
Candida albicans is both a major fungal pathogen and a member of the commensal human microflora. The morphological switch from yeast to hyphal growth is associated with disease and many environmental factors are known to influence the yeast-to-hyphae switch. The
Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation
de la Roche M, et al.
The Journal of Cell Biology, 217(10), 3560-3576 (2018)
Pharmacology of adenosine receptors and their signaling role in immunity and inflammation
Pharmacology & Therapeutics, 21(3), 245-253 (2014)
Daniele Ferrante et al.
Cell reports, 35(11), 109248-109248 (2021-06-17)
Loss-of-function mutations in proline-rich transmembrane protein-2 (PRRT2) cause paroxysmal disorders associated with defective Ca2+ dependence of glutamatergic transmission. We find that either acute or constitutive PRRT2 deletion induces a significant decrease in the amplitude of evoked excitatory postsynaptic currents (eEPSCs)
Conditional knockdown of proteins using auxin-inducible degron (AID) fusions in Toxoplasma gondii
Brown KM, et al.
Bio-protocol, 8(4), 245-253 (2018)
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