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Showing 1-30 of 59 results for "A6805" within Papers
Jun-ichi Onose et al.
Cellular immunology, 279(2), 140-144 (2012-12-19)
Vialinin A is an extremely potent inhibitor of tumor necrosis factor (TNF)-α release from RBL-2H3 cells. The present study investigated in detail the inhibitory effects of vialinin A and its analog, 5',6'-dimethyl-1,1':4',1″-terphenyl-2',3',4,4″-tetraol (DMT), on TNF-α. Vialinin A and DMT inhibited
Isolation of beta-N-acetylhexosaminidase, beta-N-acetylglucosaminidase, and beta-N-acetylgalactosaminidase from calf brain.
Y Z Frohwein et al.
Biochemistry, 6(9), 2775-2782 (1967-09-01)
High serum N-acetyl-ß-d-glucosaminidase activity is a predictor of 28-year mortality in a population of community-dwelling Japanese-the Tanushimaru study.
Kuniko Yoshikawa et al.
Journal of the American Geriatrics Society, 61(3), 467-468 (2013-03-19)
A M Dygai et al.
Bulletin of experimental biology and medicine, 154(2), 278-282 (2013-01-19)
We studied the effect of mobilization of bone marrow multipotent stem cells induced by intragastric administration of pegylated hyaluronate-endo-β-N-acetylhexosaminidase (Peg-HEAHA) on hemopoiesis under conditions of experimental chronic hepatitis. Peg-HEAHA increased the counts of hemopoietic precursors in the hemopoietic tissue against
Cíntia Delai da Silva Horinouchi et al.
Journal of ethnopharmacology, 145(1), 311-319 (2012-11-20)
Combretum leprosum is a species that is popularly used in Brazil as a healing agent to treat skin problems and lesions. In this study we investigated the possible potential of this extract to treat inflammatory and hyperproliferative skin conditions. Classical
Wei-Ni Zhang et al.
Journal of bioscience and bioengineering, 117(2), 153-157 (2013-09-10)
N-Acetyl-β-D-glucosaminidase (NAGase) is proved to be correlated with reproduction of male animals. In this study, enzymatic characterizations of NAGase from spermary of Nile tilapia (Oreochromis niloticus) were investigated in order to further study its reproductive function in fish. Tilapia NAGase
P Calvo et al.
The Biochemical journal, 175(2), 743-750 (1978-11-01)
1. A beta-N-acetylhexosaminidase was purified 330-fold from the digestive gland of the terrestrial mollusc Helicella ericetorum Müller. 2. Its pH optimum is 4.5 for both beta-N-acetylglucosaminidase and beta-N-acetylgalactosaminidase activities in two buffer solutions; it is fully stable at 37 degrees
Tyler Mark Pierson et al.
Molecular genetics and metabolism, 108(1), 65-69 (2012-11-20)
A 12 year-old female presented with a seven-year history of progressive muscle weakness, atrophy, tremor and fasciculations. Cognition was normal. Rectal biopsy revealed intracellular storage material and biochemical testing indicated low hexosaminidase activity consistent with juvenile-onset G(M2)-gangliosidosis. Genetic evaluation revealed
Federica Vernuccio et al.
Recenti progressi in medicina, 103(12), 559-563 (2012-12-22)
Cardiorenal syndrome is a pathophysiological heart and kidney disorder, in which acute or chronic dysfunction of one organ induces a damage in the other. It's a syndrome more and more often encountered in clinical practice and this implies the need
David J Vocadlo
Current opinion in chemical biology, 16(5-6), 488-497 (2012-11-14)
The addition of N-acetylglucosamine (GlcNAc) O-linked to serine and threonine residues of proteins is known as O-GlcNAc. This post-translational modification is found within multicellular eukaryotes on hundreds of nuclear and cytoplasmic proteins. O-GlcNAc transferase (OGT) installs O-GlcNAc onto target proteins
Erica W Taylor et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(1), 10-21 (2014-01-02)
Serine phosphorylation of AMPA receptor (AMPAR) subunits GluA1 and GluA2 modulates AMPAR trafficking during long-term changes in strength of hippocampal excitatory transmission required for normal learning and memory. The post-translational addition and removal of O-linked β-N-acetylglucosamine (O-GlcNAc) also occurs on
Cloning and Expression of the beta-N-Acetylglucosaminidase Gene from Streptococcus pneumoniae GENERATION OF TRUNCATED ENZYMES WITH MODIFIED AGLYCON SPECIFICITY
Clarke V, et al.
The Journal of Biological Chemistry, 270(15), 8805-8814 (1995)
Mutational studies on endo-beta-N-acetylglucosaminidase D which hydrolyzes core portion of asparagine-linked complex type oligosaccharides
Yamamoto S, et al.
Glycoconjugate Journal, 22(1-2), 35-42 (2005)
Yoosoo Yang et al.
The Biochemical journal, 450(3), 537-546 (2012-12-21)
Anti-allergic effects of dietary polyphenols were extensively studied in numerous allergic disease models, but the molecular mechanisms of anti-allergic effects by polyphenols remain poorly understood. In the present study, we show that the release of granular cargo molecules, contained in
Manuela Mellone et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(46), 18175-18189 (2013-11-15)
Intracellular tau aggregates are the neuropathological hallmark of several neurodegenerative diseases, including Alzheimer's disease, progressive supranuclear palsy, and cases of frontotemporal dementia, but the link between these aggregates and neurodegeneration remains unclear. Neuronal models recapitulating the main features of tau
Colin R Jackson et al.
Journal of visualized experiments : JoVE, (80)(80), doi:10-doi:10 (2013-10-15)
Much of the nutrient cycling and carbon processing in natural environments occurs through the activity of extracellular enzymes released by microorganisms. Thus, measurement of the activity of these extracellular enzymes can give insights into the rates of ecosystem level processes
Francesco V Rao et al.
Open biology, 3(10), 130021-130021 (2013-10-04)
The dynamic modification of proteins by O-linked N-acetylglucosamine (O-GlcNAc) is an essential posttranslational modification present in higher eukaryotes. Removal of O-GlcNAc is catalysed by O-GlcNAcase, a multi-domain enzyme that has been reported to be bifunctional, possessing both glycoside hydrolase and
Young-Il Jeong et al.
Biochemical and biophysical research communications, 445(3), 549-555 (2014-02-11)
Previous studies demonstrated that Clonochis sinensis-derived crude antigens suppress development of allergic responses. We investigated the effects of C. sinensis venom allergen-like (CsVAL) proteins on immune-modulating activities in allergic inflammatory response. Using RBL-2H3 rat mast cells, we demonstrated that CsVAL
Hyung Ho Lee et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 69(Pt 2), 115-117 (2013-02-07)
β-N-acetylglucosaminidase (NagA) protein hs a chitin-degrading activity and chitin is one of the most abundant polymers in nature. NagA contains a family 3 glycoside (GH3)-type N-terminal domain and a unique C-terminal domain. The structurally uncharacterized C-terminal domain of NagA may
Suman Kumar Halder et al.
Journal of bioscience and bioengineering, 117(2), 170-177 (2013-09-03)
Production and optimization of β-N-acetyl glucosaminidase and chitinase by Ca-alginate immobilized Aeromonas hydrophila SBK1 was carried out using prawn shell as cost-effective substrate. Beads prepared with 5.0% Na-alginate (containing 2.0% colloidal chitin) and 1.0 M CaCl2 showed considerable beads integrity and
Ting-Wen A Lee et al.
Diabetes, 62(5), 1537-1546 (2013-01-17)
Previous studies have demonstrated that Fyn knockout (FynKO) mice on a standard chow diet display increased glucose clearance and whole-body insulin sensitivity associated with decreased adiposity resulting from increased fatty acid use and energy expenditure. Surprisingly, however, despite a similar
Douglas N Sanders et al.
Molecular genetics and metabolism, 108(1), 70-75 (2012-12-26)
GM2 gangliosidosis is a fatal lysosomal storage disease caused by a deficiency of β-hexosaminidase (EC 3.2.1.52). There are two major isoforms of the enzyme: hexosaminidase A composed of an α and a β subunit (encoded by HEXA and HEXB genes
Seon-Young Han et al.
The Journal of nutrition, 143(5), 632-639 (2013-03-22)
Resveratrol is a phytoalexin abundantly found in red grape skin and is effective in antitumor and antiinflammation associated with immune responses. This study investigated whether resveratrol suppressed immunoglobulin (Ig)E-mediated allergic responses and passive cutaneous anaphylaxis (PCA) in rat RBL-2H3 mast
Beata Zalewska-Szajda et al.
Postepy higieny i medycyny doswiadczalnej (Online), 67, 996-999 (2013-10-04)
Type 1 diabetes is one of the most common chronic diseases in children. The aim of the study was to evaluate the catabolism of glycoconjugates in saliva of children with type 1 diabetes, by measurement of the activity of N-acetyl-β-D-hexosaminidase
Fernanda A Araújo et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 121(5), 422-430 (2012-11-28)
Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, have been shown to ameliorate a number of vascular diseases. We evaluated the inflammatory and angiogenic components of the fibrovascular tissue induced by subcutaneous implants in mice and their modulation by fluvastatin. Our
Reply: To PMID 22269724.
Kent Doi et al.
The Annals of thoracic surgery, 96(3), 1127-1127 (2013-09-03)
Yasuhiro Ogawa et al.
PloS one, 8(1), e55856-e55856 (2013-02-06)
Sandhoff disease (SD) is a glycosphingolipid storage disease that arises from mutations in the Hexb gene and the resultant deficiency in β-hexosaminidase activity. This deficiency results in aberrant lysosomal accumulation of the ganglioside GM2 and related glycolipids, and progressive deterioration
Benjamin Pluvinage et al.
Journal of molecular biology, 425(2), 334-349 (2012-11-17)
Streptococcus pneumoniae is a serious human pathogen that presents on its surface numerous proteins involved in the host-bacterium interaction. The carbohydrate-active enzymes are particularly well represented among these surface proteins, and many of these are known virulence factors, highlighting the
Anna Hogmalm et al.
American journal of physiology. Lung cellular and molecular physiology, 306(1), L23-L34 (2013-11-05)
Perinatal inflammation and the inflammatory cytokine IL-1 can modify lung morphogenesis. To examine the effects of antenatal expression of IL-1β in the distal airway epithelium on fetal lung morphogenesis, we studied lung development and surfactant expression in fetal mice expressing
A M Dygai et al.
Bulletin of experimental biology and medicine, 153(5), 684-688 (2012-11-01)
Pegylated hyaluronate-endo-β-N-acetylhexosaminidase considerably potentiates the hemostimulating effects of erythropoietin due to intensification of proliferation and differentiation of erythroid precursors against the background of enhanced secretion of hemopoietins by nonadherent hemopoiesis-inducing environment cells and elevation of serum erythropoietin concentration. The use
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