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Showing 1-30 of 1807 results for "A8097" within Papers
Chih-Ru Lin et al.
American journal of physiology. Lung cellular and molecular physiology, 317(6), L791-L804 (2019-07-18)
Pulmonary emphysema is characterized by alveolar type II (ATII) cell death, destruction of alveolar wall septa, and irreversible airflow limitation. Cigarette smoke induces oxidative stress and is the main risk factor for this disease development. ATII cells isolated from nonsmokers
Ajikumaran Nair Sadasivan Nair et al.
PloS one, 15(6), e0235221-e0235221 (2020-06-26)
Ficus krishnae stem bark and leaves are used for diabetes treatment in traditional medicines. Stem bark of F. krishnae was sequentially extracted with hexane, methanol and water, and these extracts were tested for their antihyperglyceamic activity by oral glucose tolerance
Kandasamy Saravanakumar et al.
Journal of photochemistry and photobiology. B, Biology, 185, 126-135 (2018-06-11)
This article reports the utilization of seed extract (GSE) from Gardenia jasminoides Ellis. in the synthesis of silver nanoparticles (Gs-AgNPs) with versatile biological activities. The synthesized Gs-AgNPs were spherical in shape, crystal lattice with an average size of 20 nm as
Anna Cb Oliveira et al.
Journal of biomaterials applications, 32(9), 1265-1275 (2018-02-25)
Development of biomaterials' substitutes and/or equivalents to mimic normal tissue is a current challenge in tissue engineering. Thus, three-dimensional cell culture using type I collagen as a polymeric matrix cell support designed to promote cell proliferation and differentiation was employed
Manoranjan Arakha et al.
Free radical biology & medicine, 110, 42-53 (2017-05-23)
The physico-chemical properties of nanoparticle (NP), such as particle size, surface defects, crystallinity and accessible surface, affect NP photocatalytic activity that in turn defines the NP cytotoxic propensity. Since zinc oxide nanoparticle (ZnONP) energy band gap falls in a range
Jing Zhou et al.
Autophagy, 11(8), 1259-1279 (2015-06-27)
Autophagy inhibition has been widely accepted as a promising therapeutic strategy in cancer, while the lack of effective and specific autophagy inhibitors hinders its application. Here we found that liensinine, a major isoquinoline alkaloid, inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome
Tomohiro Furukawa et al.
Cell chemical biology, 27(11), 1396-1409 (2020-09-06)
Aflatoxin contamination of crops is a serious problem worldwide. Utilization of aflatoxin production inhibitors is attractive, as the elucidation of their modes of action contributes to clarifying the mechanism of aflatoxin production. Here, we identified mitochondrial protease ClpP as the
Hengwei Liu et al.
Reproduction (Cambridge, England), 153(6), 809-820 (2017-03-30)
Endometriosis is a benign gynecological disease that shares some characteristics with malignancy like migration and invasion. It has been reported that both hypoxia-inducible factor-1α (HIF-1α) and autophagy were upregulated in ectopic endometrium of patients with ovarian endometriosis. However, the crosstalk
T Kitisin et al.
BMC microbiology, 21(1), 42-42 (2021-02-11)
Scedosporium species are a group of pathogenic fungi, which can be found worldwide around high human-impacted areas. Infections of Scedosporium have been reported in several immunocompromised and immunocompetent patients with a high mortality rate. Recently, we have isolated and identified
Qian Liu et al.
Food & function, 10(9), 6157-6169 (2019-09-11)
Chicoric acid (CA), a major nutraceutical component of a typical Mediterranean vegetable, chicory, possesses excellent antioxidant and anti-inflammatory bioactivities. This work aimed to elucidate the effects of CA on neuron survival against inflammation and the underlying molecular mechanisms. Results demonstrated
Suma K Pawar et al.
Journal of molecular recognition : JMR, 33(1), e2812-e2812 (2019-09-19)
Polyphenols are secondary plant metabolites, which have received much attention because of their potential health benefits. Silibinin (SIL) is a well-known naturally occurring flavonolignan, which is extensively used in treating a wide variety of diseases as a dietary supplement as
Manuela Gómez-Gaviria et al.
Journal of fungi (Basel, Switzerland), 6(2) (2020-05-06)
The secretory pathway in Candida albicans involves the protein translocation into the lumen of the endoplasmic reticulum and transport to the Golgi complex, where proteins undergo posttranslational modifications, including glycosylation and proteolysis. The Golgi-resident Kex2 protease is involved in such
Jie Yang et al.
Toxicology letters, 265, 131-139 (2016-12-08)
Pegylated liposomal doxorubicin (PLD) has been approved to treat patients with various types of cancers because it rarely caused side effects, such as cardiotoxicity, in comparison to doxorubicin, but it frequently results in hand-foot syndrome (HFS). This may affect the
W Bielas et al.
Theriogenology, 102, 59-66 (2017-07-28)
This study investigated the effect of exposure to zearalenone (ZEN) and its metabolites on the characteristics of epididymal spermatozoa, testicular and epididymal biometry and histology, and the concentration of testosterone in blood plasma in male wild boars. The study was
Yuuka Fukui et al.
Colloids and surfaces. B, Biointerfaces, 136, 168-174 (2015-09-21)
We developed a mineral cross-linking strategy to prepare a biopolymer-based nanoparticle using calcium phosphate (CaP) as a cross-linker. Nanoparticles were first formed by mixing deoxyribonucleic acid (DNA) with cationic surfactants, and were cross-linked by CaP precipitation. After removal of the
Mihwa Kim et al.
Autophagy, 13(1), 149-168 (2016-10-19)
Recent progress in chemotherapy has significantly increased its efficacy, yet the development of chemoresistance remains a major drawback. In this study, we show that GFRA1/GFRα1 (GDNF family receptor α 1), contributes to cisplatin-induced chemoresistance by regulating autophagy in osteosarcoma. We
Min Seok Song et al.
International journal of molecular sciences, 19(4) (2018-04-05)
Voltage-gated potassium (Kv) channels, including Kv3.1 and Kv3.4, are known as oxygen sensors, and their function in hypoxia has been well investigated. However, the relationship between Kv channels and tumor hypoxia has yet to be investigated. This study demonstrates that
Jia Sin Ong et al.
Probiotics and antimicrobial proteins, 12(1), 125-137 (2019-01-20)
This study aimed to elucidate the targets and mechanisms of anti-staphylococcal effects from bioactive metabolites produced by lactic acid bacteria. We aimed to better understand the safety and efficacy of these bioactive metabolites in in vivo systems, typically at topical
Bindu Hegde et al.
Journal of immunology (Baltimore, Md. : 1950), 200(10), 3556-3567 (2018-04-04)
Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica (CS). Leukotriene B4 (LTB4) plays an important role in neutrophilic inflammation, which drives silicosis and promotes lung cancer. In this study, we examined the mechanisms involved in
Nitisha Sangodkar et al.
Environmental monitoring and assessment, 192(6), 397-397 (2020-05-29)
This paper describes the prevalence of indicator and pathogenic bacterial groups in water and sediments in OSZ-offshore, ISZ-inshore, IEZ-inner estuary, and UEZ-upper estuary along the river Chapora, central west coast of India, which is influenced by anthropogenic inputs. The abundance
Libor Streit et al.
Plastic and reconstructive surgery, 139(3), 670e-682e (2017-02-25)
Lipomodeling is a technique that uses the patient's own fat for tissue regeneration and augmentation. The extent of regenerative effect is reported to be determined by the numbers of adipose-derived stem cells and the viability of cells in processed adipose
T V Kuznetzova et al.
Genetika, 48(4), 451-456 (2012-06-27)
A novel phenomenon of unusual selective acridine orange (AO) staining ofpericentromeric heterochromatin regions (HRs) in chromosomal preparations from tissue with known spontaneous mitotic activity (chorionic villi, placenta, embryonic tissues, bone marrow, and testes), as well as embryonic stem cells, is
Martin Schulze et al.
Journal of reproductive immunology, 131, 13-20 (2018-11-10)
The aim of the present study was to characterize the lysozyme concentration and the bacterial killing activity (BKA) of boar seminal plasma against E. coli and S. aureus in 119 fertile Pietrain boars (aged: 18.1 ± 10.5 months). Lysozyme concentration was 2.4 ± 1.2 μg/ml
Lingxia Shi et al.
ACS biomaterials science & engineering, 6(8), 4595-4603 (2021-01-19)
The exploration of metal-organic frameworks (MOFs) with good biocompatibility and physiological stability as carrier platforms for biomedical applications is of great importance but remains challenging. Herein, we developed an in situ biomimetic mineralization strategy on zeolitic imidazolate framework (ZIF) nanocrystals
Yuwei Hao et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 19(16), 2107-2112 (2018-03-16)
To overcome the low efficiency of single-responsive smart surfaces, we have constructed a dual-responsive smart surface - poly(spiropyran-co-N-isopropylacrylamide) (poly(SP-co-NiPAAm))-grafted silicon nanowire arrays - by combining photo-responsive SP and thermo-responsive NiPAAm units for enhancing the efficiencies of cancer-cell capture and release.
Jing Wen et al.
International journal of molecular medicine, 37(1), 126-132 (2015-11-18)
Orexins are a class of peptides which have a potent influence on a broad variety of cancer cells. Autophagy is closely associated with tumors; however, its function is not yet completely understood. In this study, we aimed to determine whether
Shannon Kelly et al.
PloS one, 15(4), e0218880-e0218880 (2020-04-09)
People with sickle cell disease (SCD) are reported to have low rates of HIV infection, slower progression to AIDS and lower HIV-associated mortality compared to the general population. Mechanisms of potential resistance to HIV in SCD are incompletely understood. We
Sedigheh Eskandari et al.
Journal of cellular biochemistry, 120(6), 10128-10136 (2018-12-15)
Tyrosine kinase inhibitor (TKI)-based therapy has created promising results among much chronic myeloid leukemia (CML) patients. Imatinib as a relatively specific inhibitor of Bcr-Abl is at present one of the undisputed therapeutic agent for newlydiagnosed patients with CML. However, the
M Mahdavi et al.
Human & experimental toxicology, 37(10), 1105-1116 (2018-02-13)
Recent studies have reported the potential of pyrano-pyridine compounds in inhibiting cell growth and apoptosis induction in cancer cells. Here, we investigated the effect of new pyrano-pyridine derivatives on proliferation, oxidative damages, and apoptosis in K562 leukemia cells. Among different
Ana T Antunes et al.
PLoS genetics, 11(7), e1005326-e1005326 (2015-07-02)
Mutations in ribosomal protein (RP) genes can result in the loss of erythrocyte progenitor cells and cause severe anemia. This is seen in patients with Diamond-Blackfan anemia (DBA), a pure red cell aplasia and bone marrow failure syndrome that is
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