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Showing 1-30 of 273 results for "B2629" within Papers
M F Abdelmalek et al.
The American journal of gastroenterology, 96(9), 2711-2717 (2001-09-25)
No effective therapy currently exists for patients with nonalcoholic steatohepatitis (NASH). Betaine, a naturally occurring metabolite of choline, has been shown to raise S-adenosylmethionine (SAM) levels that may in turn play a role in decreasing hepatic steatosis. Our aim was
Sharon E Jacob et al.
Dermatitis : contact, atopic, occupational, drug, 19(3), 157-160 (2008-07-17)
Cocamidopropyl betaine (CAPB) is an amphoteric synthetic detergent that has been increasingly used in cosmetics and personal hygiene products (eg, shampoos, contact lens solutions, toothpaste detergents, makeup removers, bath gels, skin care products, cleansers, liquid soaps, antiseptics, and gynecologic and
Sinjan Choudhary et al.
Scientific reports, 5, 17599-17599 (2015-12-01)
We have studied here using a number of biophysical tools the effects of osmolytes, betaine, citrulline, proline and sorbitol which differ significantly in terms of their physical characteristics such as, charge distribution, polarity, H-bonding abilities etc, on the fibrillation of
R De Smet et al.
Clinical chemistry, 47(5), 901-909 (2001-04-28)
Several studies have pointed to a release of drugs or protein-bound solutes from their binding sites during heparinization. The effect is attributed to the metabolism of triglycerides to free fatty acids (FFAs), which compete with drugs for protein binding sites.
Stephen A Kempson et al.
Pflugers Archiv : European journal of physiology, 449(3), 227-234 (2004-09-29)
Cells in the kidney inner medulla are routinely exposed to high extracellular osmolarity during normal operation of the urinary concentrating mechanism. One adaptation critical for survival in this environment is the intracellular accumulation of organic osmolytes to balance the osmotic
Cord C Uphoff et al.
PloS one, 10(4), e0125622-e0125622 (2015-05-01)
Contaminations of cell cultures with microbiological organisms are well documented and can be managed in cell culture laboratories applying reliable detection, elimination and prevention strategies. However, the presence of viral contaminations in cell cultures is still a matter of debate
Aaron Fox et al.
FEMS microbiology ecology, 90(1), 78-91 (2014-06-27)
Plants rely on microorganisms to mobilize organically and inorganically bound sulfur (S) and phosphorus (P) in which the plant can then readily utilize. The aim of this study was to investigate the role of S- and P-mobilizing bacteria in plant
Thomas R Silvers et al.
Biochemistry, 52(51), 9367-9374 (2013-11-13)
The formation and stability of protein-protein interfaces are of obvious biological importance. While a large body of literature exists describing the effect of osmolytes on protein folding, very few studies address the effect of osmolytes on protein association and binding.
Shu-Jung Lai et al.
Plant molecular biology, 85(4-5), 429-441 (2014-05-08)
Glycine betaine (betaine) has the highest cellular osmoprotective efficiency which does not accumulate in most glycophytes. The biosynthetic pathway for betaine in higher plants is derived from the oxidation of low-accumulating metabolite choline that limiting the ability of most plants
Jason W Sahl et al.
PloS one, 10(3), e0121052-e0121052 (2015-03-25)
Burkholderia pseudomallei is the causative agent of melioidosis and a potential bioterrorism agent. In the development of medical countermeasures against B. pseudomallei infection, the US Food and Drug Administration (FDA) animal Rule recommends using well-characterized strains in animal challenge studies.
Mariana Figuera-Losada et al.
PloS one, 10(5), e0124481-e0124481 (2015-05-27)
Ceramide is a bioactive lipid that plays an important role in stress responses leading to apoptosis, cell growth arrest and differentiation. Ceramide production is due in part to sphingomyelin hydrolysis by sphingomyelinases. In brain, neutral sphingomyelinase 2 (nSMase2) is expressed
Valeria Tomati et al.
Scientific reports, 5, 12138-12138 (2015-07-18)
Cystic fibrosis (CF) is caused by mutations in the CFTR chloride channel. Deletion of phenylalanine 508 (F508del), the most frequent CF mutation, impairs CFTR trafficking and gating. F508del-CFTR mistrafficking may be corrected by acting directly on mutant CFTR itself or
Tanja Kostić et al.
Applied microbiology and biotechnology, 99(18), 7711-7722 (2015-08-01)
In a clinical setting, molecular assays such as polymerase chain reaction offer a rapid means to infer or confirm identity and therapeutic decisions. Accordingly, a number of molecular assays targeting identity and antibiotic resistance (AR) genes have been developed; however
Joachim Jankowski et al.
Arteriosclerosis, thrombosis, and vascular biology, 23(7), 1231-1238 (2003-05-10)
Diadenosine polyphosphates have been demonstrated to be involved in the control of vascular tone as well as the growth of vascular smooth muscle cells and hence, possibly, in atherogenesis. In this study we investigated the question of whether diadenosine polyphosphates
Kim M Yonemori et al.
The Journal of nutrition, 143(6), 894-899 (2013-04-26)
Choline and betaine are important nutrients for human health, but reference food composition databases for these nutrients became available only recently. We tested the feasibility of using these databases to estimate dietary choline and betaine intakes among ethnically diverse adults
Yabing Duan et al.
Scientific reports, 4, 7094-7094 (2014-11-19)
Resistance of Fusarium graminearum to carbendazim is caused by point mutations in the β2-tubulin gene. The point mutation at codon 167 (TTT → TAT, F167Y) occurs in more than 90% of field resistant isolates in China. To establish a suitable
S Mukherjee et al.
International journal of cosmetic science, 37(4), 371-378 (2015-02-07)
Skin irritation in personal cleansing has been correlated with surfactant binding with stratum corneum proteins. Polar and non-polar oils are increasingly being used in cleansing formulations which contain high (10-15%) level of anionic and non-ionic surfactants. However, the effects of
Guilherme S Mazzini et al.
Pancreas, 44(4), 619-625 (2015-03-31)
Extracellular purines are a component of the systemic inflammatory response, and their levels are modulated by ectonucleotidases. In addition, nucleotide hydrolysis releases phosphate. We studied serum phosphate levels as a predictor of severity in acute pancreatitis (AP) and their correlation
Lance R Parsons et al.
mBio, 6(2) (2015-04-02)
Herpes simplex virus (HSV) is a widespread pathogen that causes epithelial lesions with recurrent disease that manifests over a lifetime. The lifelong aspect of infection results from latent viral infection of neurons, a reservoir from which the virus reactivates periodically.
Tom Vander Hoogerstraete et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(33), 11757-11766 (2015-07-17)
In a conventional solvent extraction system, metal ions are distributed between two immiscible phases, typically an aqueous and an organic phase. In this paper, the proof-of-principle is given for the distribution of metal ions between three immiscible phases, two ionic
Wolfram Gronwald et al.
Kidney international, 79(11), 1244-1253 (2011-03-11)
Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used multidimensional-multinuclear nuclear magnetic resonance (NMR) spectroscopy with support vector machine-based
Michaela S Lesjak et al.
Cell adhesion & migration, 8(5), 499-508 (2014-12-09)
Endometrial carcinoma differential 3 (EDI3) was the first member of the glycerophosphodiesterase (GDE) protein family shown to be associated with cancer. Our initial work demonstrated that endometrial and ovarian cancer patients with primary tumors overexpressing EDI3 had a higher risk
Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients.
S C Hung et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 38(5), 941-947 (2001-10-31)
Patients with end-stage renal disease undergoing regular dialysis are prone to encephalopathy, but the cause is often unclear. Dialysis patients are at risk for thiamine deficiency, which may mimic many uremic complications, including encephalopathy. To determine whether unexplained encephalopathy in
Ya-Bing Duan et al.
PloS one, 9(10), e111094-e111094 (2014-10-21)
Botrytis cinerea is a devastating plant pathogen that causes grey mould disease. In this study, we developed a visual detection method of B. cinerea based on the Bcos5 sequence using loop-mediated isothermal amplification (LAMP) with hydroxynaphthol blue dye (HNB). The
Savvas Petanidis et al.
Cancer letters, 335(2), 387-396 (2013-03-12)
Vanadium is known for its antitumorigenicity. Poised to investigate the impact of well-defined forms of vanadium on processes and specific biomolecules (oncogenes-proteins) involved in cancer cell physiology, a novel ternary V(V)-peroxido-betaine compound was employed in experiments targeting cell viability, apoptosis
Lars Hoffmann et al.
American journal of physiology. Gastrointestinal and liver physiology, 304(9), G835-G846 (2013-03-02)
Betaine critically contributes to the control of hepatocellular hydration and provides protection of the liver from different kinds of stress. To investigate how the hepatocellular hydration state affects gene expression of enzymes involved in the metabolism of betaine and related
Lei Gao et al.
International journal of molecular sciences, 22(14) (2021-07-25)
The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries
Vishnudutt Purohit et al.
The American journal of clinical nutrition, 86(1), 14-24 (2007-07-10)
This report is a summary of a symposium on the role of S-adenosylmethionine (SAM), betaine, and folate in the treatment of alcoholic liver disease (ALD), which was organized by the National Institute on Alcohol Abuse and Alcoholism in collaboration with
Yixing Zhai et al.
The international journal of biochemistry & cell biology, 65, 12-19 (2015-05-20)
Ribonuclease like 5 (Rnasel5) is a novel member of the zebrafish ribonuclease A family and its expression is increased during early embryogenesis. However, the in vivo biological function of Rnasel5 remains to be elucidated. Here, we report that knockdown of
Strategies to improve medication reconciliation.
Oscar M P Jolobe
The American journal of medicine, 126(12), e49-e49 (2013-11-23)
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