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Showing 1-30 of 83 results for "B85307" within Papers
Jan Peetz et al.
Pflugers Archiv : European journal of physiology, 467(7), 1469-1480 (2014-08-15)
Blood-derived lactate is a precious energy substrate for the heart muscle. Lactate is transported into cardiomyocytes via monocarboxylate transporters (MCTs) together with H(+), which couples lactate uptake to cellular pH regulation. In this study, we have investigated how the interplay
Diacetyl exposure at a food flavoring production facility.
Kenneth R Lee
Journal of occupational and environmental hygiene, 9(4), D59-D62 (2012-03-21)
Delphine Passerini et al.
International journal of food microbiology, 160(3), 329-336 (2013-01-08)
Lactococcus lactis subsp. lactis biovar diacetylactis strains are used in the dairy industry for generating acetoin and notably diacetyl which imparts a high level of buttery flavor notes. A collection of domesticated and environmental strains was screened for the production
A A Roĭ et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 74(5), 74-80 (2012-11-06)
It has been shown that bacteria of the genus Bacillus inhibited the development of infection caused by Clavibacter michiganensis subsp. michiganensis, in tomatoes. Pre-sowing seed treatment with suspensions of Bacillus subtilis IMV B-7023 and Bacillus pumilus 3 enhanced resistance of
L C Sellin et al.
Pharmacology & toxicology, 74(6), 305-313 (1994-06-01)
2,3-Butanedione monoxime, also known as diacetyl monoxime, is a nucleophilic agent which dephosphorylates acetylcholinesterase poisoned with organophosphates. This "chemical phosphatase" activity stimulated studies of the effect of 2,3-butanedione monoxime on phosphorylation-dependent cellular processes. As a result of these studies, we
Jingqun Zhang et al.
The Biochemical journal, 461(1), 99-106 (2014-04-25)
CASQ2 (cardiac calsequestrin) is commonly believed to serve as the SR (sarcoplasmic reticulum) luminal Ca2+ sensor. Ablation of CASQ2 promotes SCWs (spontaneous Ca2+ waves) and CPVT (catecholaminergic polymorphic ventricular tachycardia) upon stress but not at rest. How SCWs and CPVT
B K Hayes et al.
The Journal of biological chemistry, 264(32), 19443-19448 (1989-11-15)
We and others have recently described 9-O-acetyl-sialic acid esterase (9-O-Ac-SA esterase) activities that appear to be specific for removal of O-acetyl esters from the 9-position of naturally occurring sialic acids. We have now examined a variety of species for such
Asuka Nishino et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 184, 156-162 (2015-03-12)
After pre-exposure to the odorant diacetyl, the nematode Caenorhabditis elegans showed a decline in chemotactic responses to diacetyl, a phenomenon known as diacetyl adaptation. In the present study, we found that the established period of diacetyl adaptation in nematodes increased
Ik-Hwan Um et al.
The Journal of organic chemistry, 78(17), 8689-8695 (2013-08-07)
This paper comprises results of our investigation of the α-effect phenomenon for the reaction of O-p-nitrophenyl thionobenzoate (PNPTB) with butane-2,3-dione monoximate (Ox(-), α-nucleophile) and p-chlorophenoxide (p-ClPhO(-), normal-nucleophile) in DMSO-H2O mixtures of varying compositions at 15.0 °C, 25.0 °C, and 35.0
Stefan Irmler et al.
Applied and environmental microbiology, 79(4), 1309-1315 (2012-12-18)
The ability to produce diacetyl from pyruvate and l-serine was studied in various strains of Pediococcus pentosaceus and Pediococcus acidilactici isolated from cheese. After being incubated on both substrates, only P. pentosaceus produced significant amounts of diacetyl. This property correlated
V S Kuz'min et al.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98(9), 1119-1130 (2013-01-09)
In this study, conduction of excitation in the rat left atrial and pulmonary veins myocardium was assessed by the optical mapping technique. Rat atrial myocardium and pulmonary vein myocardium demonstrated weak differences in the activation time and conduction velocity. Maximal
Alice W Racca et al.
Human molecular genetics, 24(12), 3348-3358 (2015-03-06)
Distal arthrogryposis is the most common known heritable cause of congenital contractures (e.g. clubfoot) and results from mutations in genes that encode proteins of the contractile complex of skeletal muscle cells. Mutations are most frequently found in MYH3 and are
Randy M Wadkins et al.
Journal of medicinal chemistry, 48(8), 2906-2915 (2005-04-15)
Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics. Because the structural and amino acid homology among esterases of different classes, the identification of selective inhibitors of these proteins has proved problematic. Using Telik's target-related affinity profiling (TRAP)
Philip Harber et al.
Toxicological reviews, 25(4), 261-272 (2007-02-10)
Diacetyl is a diketone flavouring agent that is commonly employed for buttery taste as well as other purposes. Industrial exposure to flavouring agents, particularly diacetyl, has recently been associated with bronchiolitis obliterans, a severe respiratory illness producing fibrosis and obstruction
Irina Sokolchik et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(4), 1015-1023 (2005-01-28)
Caenorhabditis elegans OCR-2 (OSM-9 and capsaicin receptor-related) is a TRPV (vanilloid subfamily of transient receptor potential channel) protein that regulates serotonin (5-HT) biosynthesis in chemosensory neurons and also mediates olfactory and osmotic sensation. Here, we identify the molecular basis for
Still searching for better butter flavoring.
Carol Potera
Environmental health perspectives, 120(12), A457-A457 (2012-12-06)
S D Aunsbjerg et al.
International journal of food microbiology, 194, 46-53 (2014-12-03)
Lactic acid bacteria with antifungal properties can be used to control spoilage of food and feed. Previously, most of the identified metabolites have been isolated from cell-free fermentate of lactic acid bacteria with methods suboptimal for detecting possible contribution from
Hai-Tao Yang et al.
The Journal of organic chemistry, 78(3), 1163-1170 (2013-01-08)
One-step DMAP-catalyzed [3 + 2] and [4 + 2] cycloaddition reactions between C(60) and unmodified Morita-Baylis-Hillman adducts in the presence of Ac(2)O have been developed for the easy preparation of cyclopentene- and cyclohexene-fused [60]fullerene derivatives. When the MBH adducts bear
Nobuo Ochiai et al.
Journal of chromatography. A, 1421, 103-113 (2015-08-16)
An extension of multi-volatile method (MVM) technology using the combination of a standard dynamic headspace (DHS) configuration, and a modified DHS configuration incorporating an additional vacuum module, was developed for milliliter injection volume of aqueous sample with full sample evaporation.
Asuka Takeishi et al.
eLife, 9 (2020-10-20)
Internal state alters sensory behaviors to optimize survival strategies. The neuronal mechanisms underlying hunger-dependent behavioral plasticity are not fully characterized. Here we show that feeding state alters C. elegans thermotaxis behavior by engaging a modulatory circuit whose activity gates the
Elizabeth I Parkinson et al.
Bioorganic & medicinal chemistry, 19(15), 4635-4643 (2011-07-08)
Carboxylesterases (CE) are ubiquitous enzymes found in both human and animal tissues and are responsible for the metabolism of xenobiotics. This includes numerous natural products, as well as a many clinically used drugs. Hence, the activity of these agents is
Tetrahedron Letters, 32, 3879-3879 (1991)
Pascal Fuchsmann et al.
Journal of agricultural and food chemistry, 63(34), 7511-7521 (2015-08-01)
To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry/pulsed flame photometric detection and gas chromatography-olfactometry to identify and quantitate volatile compounds. In addition, odor quality and
Peter Kovacic et al.
Reviews of environmental contamination and toxicology, 204, 133-148 (2009-12-04)
Diacetyl, a butter-flavoring component, has recently attracted scientific and media attention because it has been implicated as an agent that induces popcorn lung disease in exposed plant workers. This disease, officially referred to as bronchiolitis obliterans, entails exposure-induced compromise to
Grażyna Bortnowska
Food chemistry, 135(3), 2021-2028 (2012-09-08)
The aim of the present study was to assess the influence of pH (3, 7 and 9) as well as ionic strength of NaCl (0mmol/l, 100mmol/l, 200mmol/l and 400mmol/l) on the retention and release characteristics of diacetyl and (-)-α-pinene in
K Kusunoki et al.
Yeast (Chichester, England), 29(10), 435-442 (2012-10-06)
The vicinal diketones (VDK), such as diacetyl and 2,3-pentandione, impart an unpleasant butter-like flavour to beer. Typically, these are required to be reduced below the flavour thresholds during the maturation (lagering) stages of the brewing process. To shorten beer maturation
M L Escamilla-Hurtado et al.
Revista latinoamericana de microbiologia, 38(2), 129-137 (1996-04-01)
Some of the most widely used products in the food industry are flavour compounds. These products can be obtained either by chemical synthesis and therefore are called synthetic or by fermentation thus called natural flavors. There is a tendency towards
M I Rincon-Delgadillo et al.
Journal of dairy science, 96(1), 105-111 (2012-10-16)
Diacetyl is used to impart a buttery flavor to numerous food products such as sour cream, cottage cheese, vegetable oil-based spreads, baked goods, and beverages. Recent studies have linked exposure to high concentrations of diacetyl and the onset of bronchiolitis
Tingting Guo et al.
PloS one, 7(4), e36296-e36296 (2012-05-05)
Lactococcus lactis is a well-studied bacterium widely used in dairy fermentation and capable of producing metabolites with organoleptic and nutritional characteristics. For fine tuning of the distribution of glycolytic flux at the pyruvate branch from lactate to diacetyl and balancing
F Steven Korte et al.
American journal of physiology. Heart and circulatory physiology, 303(7), H863-H870 (2012-08-07)
Calcium sensitivity of the force-pCa relationship depends strongly on sarcomere length (SL) in cardiac muscle and is considered to be the cellular basis of the Frank-Starling law of the heart. SL dependence may involve changes in myofilament lattice spacing and/or
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