CN
Search Within
C0406
Applied Filters:
Keyword:'C0406'
Showing 1-30 of 42 results for "C0406" within Papers
Kseniya Ustinova et al.
Journal of cell science, 136(12) (2023-06-26)
Mitotic spindle assembly during cell division is a highly regulated process. Ran-GTP produced around chromosomes controls the activity of a multitude of spindle assembly factors by releasing them from inhibitory interaction with importins. A major consequence of Ran-GTP regulation is
Ayush Saurabh et al.
The journal of physical chemistry. B (2022-06-02)
Quantitative fluorescence analysis is often used to derive chemical properties, including stoichiometries, of biomolecular complexes. One fundamental underlying assumption in the analysis of fluorescence data─whether it be the determination of protein complex stoichiometry by super-resolution, or step-counting by photobleaching, or
Mária Baranyi et al.
Journal of biotechnology, 128(2), 383-392 (2006-12-13)
Patients suffering certain metabolic diseases (e.g. phenylketonuria) need a low-phenylalanine diet throughout their lives. Transgenic rabbits were created to express low-phenylalanine kappa-casein in their milk. The aim was to demonstrate for the first time the feasibility of producing a modified
Genetic variants of bovine $\beta$-and $\kappa$-casein result in different immunoglobulin E-binding epitopes after in vitro gastrointestinal digestion
Lisson M, et al.
Journal of Dairy Science, 96, 5532-5543 (2013)
Benjamin J LaFrance et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(2) (2022-01-09)
Microtubules (MTs) are polymers of αβ-tubulin heterodimers that stochastically switch between growth and shrinkage phases. This dynamic instability is critically important for MT function. It is believed that GTP hydrolysis within the MT lattice is accompanied by destabilizing conformational changes
Stefan Niekamp et al.
The EMBO journal, 38(13), e101414-e101414 (2019-07-04)
The movement of a molecular motor protein along a cytoskeletal track requires communication between enzymatic, polymer-binding, and mechanical elements. Such communication is particularly complex and not well understood in the dynein motor, an ATPase that is comprised of a ring
Paramjit S Bansal et al.
Biochemical and biophysical research communications, 340(4), 1098-1103 (2006-01-13)
The caseins (alphas1, alphas2, beta, and kappa) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the chemical synthesis and structure elucidation of the N-terminal segment (1-44)
Control of Mozzarella spoilage bacteria by using bovine lactoferrin pepsin-digested hydrolysate
Worldwide Research Efforts in the Fighting Against Microbial Pathogens
From Basic Research to Technological Developments, 118-122 (2013)
J Sotres et al.
Caries research, 48(2), 98-110 (2013-12-04)
We show in this work how systems formed by phosphoproteins on calcium phosphate surfaces can be directly characterized, in real time, in liquid medium, without the need for elution or labeling. Specifically, we show how this is possible by applying
Tzu-Yuan Wang et al.
Food chemistry, 234, 431-438 (2017-05-30)
A total of 294 edible protein sequences and 5 commercial proteases listed in the BIOPEP database were analyzed in silico. The frequency (A), a parameter in silico described previously, was examined further to calculating the ratio of truncated peptides with
Nida Siddiqui et al.
Current biology : CB, 32(17), 3862-3870 (2022-08-13)
Intracellular transport is essential for neuronal function and survival. The most effective plus-end-directed neuronal transporter is the kinesin-3 KIF1C, which transports large secretory vesicles and endosomes.1-4 Mutations in KIF1C cause hereditary spastic paraplegia and cerebellar dysfunction in human patients.5-8 In
Amol Aher et al.
Current biology : CB, 30(11), 2175-2183 (2020-05-04)
Microtubules play a key role in cell division, motility, and intracellular trafficking. Microtubule lattices are generally regarded as stable structures that undergo turnover through dynamic instability of their ends [1]. However, recent evidence suggests that microtubules also exchange tubulin dimers
Tanja Consolati et al.
Methods in molecular biology (Clifton, N.J.), 2430, 315-336 (2022-04-28)
The γ-tubulin ring complex (γTuRC) is the major microtubule nucleator in cells. How γTuRC nucleates microtubules, and how nucleation is regulated is not understood. To gain an understanding of γTuRC activity and regulation at the molecular level, it is important
Kyoko Chiba et al.
Cell reports, 39(9), 110900-110900 (2022-06-02)
Kinesin-1 activity is regulated by autoinhibition. Intramolecular interactions within the kinesin heavy chain (KHC) are proposed to be one facet of motor regulation. The KHC also binds to the kinesin light chain (KLC), which has been implicated in both autoinhibition
Chun-Chi Chen et al.
Nanomaterials (Basel, Switzerland), 11(10) (2021-10-24)
The effects of chymosin on the physicochemical and hydrolysis characteristics of casein micelles and individual caseins were investigated. Adding 0.03 units of chymosin/mL led to the casein micelles in skim milk coagulating after a 3 h incubation period at 30
Chiara Nitride et al.
Analytical and bioanalytical chemistry, 411(16), 3463-3475 (2019-05-30)
The unintentional presence of even trace amounts of certain foods constitutes a major hazard for those who suffer from food allergies. For many food industries, product and raw ingredient surveillance forms part of their risk assessment procedures. This may require
Caterina Villa et al.
Comprehensive reviews in food science and food safety, 17(1), 137-164 (2018-01-01)
Cow milk allergy is one of the most common food allergies in early childhood and often persists through adult life, forcing an individual to a complete elimination diet. Milk proteins are present in uncounted food products, such as cheese, yogurt
Presence of functional, autoreactive human milk-specific IgE in infants with cow's milk allergy.
Jarvinen KM., et al.
Clinical and Experimental Allergy (2011)
A study on bovine kappa-casein aggregation after the enzymatic action of chymosin.
Maria Eugenia Hidalgo., et al
Colloids Surf., 76, 556-563 (2010)
Julia Grawenhoff et al.
Methods in molecular biology (Clifton, N.J.), 2431, 547-568 (2022-04-13)
Motor protein-driven transport of mRNAs on microtubules and their local translation underlie important neuronal functions such as development, growth cone steering, and synaptic plasticity. While there is abundant data on how membrane-bound cargoes such as vesicles, endosomes, or mitochondria are
Simone Talens et al.
Thrombosis and haemostasis, 119(10), 1624-1631 (2019-08-23)
Many proteins bind to fibrin during clot formation in plasma. We previously identified by mass spectrometry the most abundant proteins that noncovalently bind to fibrin clots. Several of these proteins (e.g., apolipoprotein J/clusterin, haptoglobin, α2-macroglobulin, α1-antitrypsin) can act as extracellular
Javier Martínez-Botas et al.
Methods in molecular biology (Clifton, N.J.), 2578, 219-236 (2022-09-25)
Peptide microarrays are a powerful tool to identify linear epitopes of food allergens in a high-throughput manner. The main advantages of the microarray-based immunoassay are as follows: the possibility to assay thousands of targets simultaneously, the requirement of a low
Aprianita Aprianita et al.
The Journal of dairy research, 81(2), 183-192 (2014-03-07)
This experiment was conducted to determine the effects of diets supplemented with cottonseed oil, Acacia mearnsii-condensed tannin extract, and a combination of both on composition of bovine milk. Treatment diets included addition of cottonseed oil (800 g/d; CSO), condensed tannin from
Regina L Agulto et al.
eLife, 10 (2021-07-27)
The microtubule-associated protein, doublecortin-like kinase 1 (DCLK1), is highly expressed in a range of cancers and is a prominent therapeutic target for kinase inhibitors. The physiological roles of DCLK1 kinase activity and how it is regulated remain elusive. Here, we
Javier Martínez-Botas et al.
Methods in molecular biology (Clifton, N.J.), 2344, 119-135 (2021-06-12)
Peptide microarrays have been used to study protein-protein interaction, enzyme-substrate profiling, epitope mapping, vaccine development, and immuno-profiling. Unlike proteins, peptides are cheap to produce, and can be produced in a high-throughput manner, in a reliable and consistent procedure that reduces
Stacy A Malaker et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(15), 7278-7287 (2019-03-27)
Mucin domains are densely O-glycosylated modular protein domains that are found in a wide variety of cell surface and secreted proteins. Mucin-domain glycoproteins are known to be key players in a host of human diseases, especially cancer, wherein mucin expression
Lenka Faltova et al.
Structure (London, England : 1993), 27(9), 1375-1383 (2019-07-30)
Katanin is a microtubule-severing enzyme that is crucial for many cellular processes. Katanin consists of two subunits, p60 and p80, that form a stable complex. The interaction between subunits is mediated by the p60 N-terminal microtubule-interacting and -trafficking domain (p60-MIT)
Hongjun Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(41), E9560-E9569 (2018-09-28)
The protein disaggregase ClpB hexamer is conserved across evolution and has two AAA+-type nucleotide-binding domains, NBD1 and NBD2, in each protomer. In M. tuberculosis (Mtb), ClpB facilitates asymmetric distribution of protein aggregates during cell division to help the pathogen survive
William G Hirst et al.
Current biology : CB, 30(11), 2184-2190 (2020-05-11)
The function of cellular organelles relates not only to their molecular composition but also to their size. However, how the size of dynamic mesoscale structures is established and maintained remains poorly understood [1-3]. Mitotic spindle length, for example, varies several-fold
Matthew R King et al.
Nature communications, 11(1), 270-270 (2020-01-16)
Phase separation of substrates and effectors is proposed to enhance biological reaction rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching microtubule nucleation in spindles and functions with the substrate tubulin by an unknown mechanism. Here
Page 1 of 2