Daria V Ilatovskaya et al.
American journal of physiology. Heart and circulatory physiology, 317(3), H581-H596 (2019-07-20)
The adaptive immune response is key for cardiac wound healing post-myocardial infarction (MI) despite low T-cell numbers. We hypothesized that CD8+ T-cells regulate the inflammatory response, leading to decreased survival and cardiac function post-MI. We performed permanent occlusion of the