Malgorzata Wiweger et al.
Frontiers in cellular neuroscience, 15, 647860-647860 (2021-05-15)
Niemann-Pick type C (NPC) disease is an autosomal recessive lysosomal storage disease that is caused by a mutation of the NPC1 or NPC2 gene, in which un-esterified cholesterol and sphingolipids accumulate mainly in the liver, spleen, and brain. Abnormal lysosomal