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Showing 31-60 of 2604 results for "C1231" within Papers
Jun Zhou et al.
Carbohydrate polymers, 121, 199-206 (2015-02-11)
The present study was designed to investigate the hypoglycemic activity and the potential mechanisms of Misgurnus anguillicaudatus polysaccharide (MAP) in streptozotocin-induced diabetic mice. MAP oral administration significantly decreased the blood levels of glucose, TC, TG, LDL-C, and increased the blood
Rozanne Kruger et al.
SpringerPlus, 4, 128-128 (2015-04-01)
Body mass index (BMI) (kg/m(2)) is used internationally to assess body mass or adiposity. However, BMI does not discriminate body fat content or distribution and may vary among ethnicities. Many women with normal BMI are considered healthy, but may have
Karina Fischer et al.
The American journal of clinical nutrition, 101(4), 794-807 (2015-04-04)
Visceral (VAT) and subcutaneous abdominal (SAAT) and trunk (STRAT) adipose tissue (AT) have been suggested to be differentially influenced by diet. We investigated whether and to what extent usual patterns of nutrient intake are associated with VAT, SAAT, and STRAT
Tsong-Ming Lu et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 70(4), 395-400 (2015-09-20)
Onion (Allium cepa L.) is widely employed as a food ingredient as well as traditional remedy to treat fever, burns, and scurvy. The present study focused on the modulator efficacy of the quercetin rich onion juice on lipid profile and
M Elizabeth Wilcox et al.
JAMA, 311(23), 2422-2431 (2014-06-19)
Thoracentesis is performed to identify the cause of a pleural effusion. Although generally safe, thoracentesis may be complicated by transient hypoxemia, bleeding, patient discomfort, reexpansion pulmonary edema, and pneumothorax. To identify the best means for differentiating between transudative and exudative
Tenna Jørgensen et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(6), 943-950 (2015-03-12)
It is well known that few weeks of high fat (HF) diet may induce metabolic disturbances and mitochondrial dysfunction in skeletal muscle. However, little is known about the effects of long-term HF exposure and effects on brain mitochondria are unknown.
Constance Gayet-Boyer et al.
The British journal of nutrition, 112(12), 1914-1922 (2014-10-28)
The effects of ruminant (R) trans-fatty acids (TFA) on the risk of CVD are still under debate. It could be argued that the lack of the effect of R-TFA may be the result of the small amount of their intake.
Dong-xing Xie et al.
BMJ open, 5(10), e008637-e008637 (2015-10-16)
To examine the associations between dietary zinc intake and hyperuricaemia. Cross-sectional study. This study was conducted in a health examination centre of China. A total of 5168 middle-aged and older participants (aged 40 years or above) (2697 men and 2471 women)
Changwoo Han et al.
Neuropsychiatric disease and treatment, 11, 2903-2908 (2015-12-02)
Alcohol dependence is a disorder ascribable to multiple factors and leads to cognitive impairment. Given that insulin dysregulation can cause cognitive impairment, patients with alcohol dependence are likely to develop insulin dysregulation such as that in diabetes. The purposes of
On estrogen, cholesterol metabolism, and breast cancer.
Margaret Warner et al.
The New England journal of medicine, 370(6), 572-573 (2014-02-07)
Bjørn H Ebdrup et al.
The Journal of clinical psychiatry, 75(9), e899-e905 (2014-10-09)
Treatment with antipsychotic drugs is widely associated with metabolic side effects such as weight gain and disturbed glucose metabolism, but the pathophysiologic mechanisms are unclear. Fifty nondiabetic (fasting plasma glucose ≤ 7.0 mmol/L), antipsychotic-treated male patients (ICD-10 diagnosis code F20
Dong Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 179-184 (2013-12-18)
Model phospholipid membranes and vesicles have long provided insight into the nature of confined materials and membranes while also providing a platform for drug delivery. The rich thermodynamic behavior and interesting domain shapes in these membranes have previously been mapped
Hugo You-Hsien Lin et al.
Clinical chemistry and laboratory medicine, 53(1), 73-83 (2014-08-26)
Tubulointerstitial damage is a final common pathway of most renal diseases. Whether urinary neutrophil gelatinase-associated lipocalin (uNGAL), a biomarker for renal tubular damage, is of prognostic value for clinical outcomes in chronic kidney disease (CKD) patients has not been well
Mei-Ling Yeh et al.
Western journal of nursing research, 37(12), 1517-1530 (2014-09-04)
Auricular acupoint stimulation has become a popular weight loss method. However, its efficacy for obesity treatment has not been fully studied. This study aimed to investigate the effect of a 10-week intervention of auricular electrical stimulation combined with auricular acupressure
Seyedeh Hoda Alavizadeh et al.
International journal of pharmaceutics, 473(1-2), 326-333 (2014-07-23)
SPI-077, cisplatin stealth liposome, is the best illustration of poor cisplatin release from liposomes and the subsequent negligible therapeutic activity. For this reason, optimizing drug release kinetics is desirable. In this report, cisplatin was encapsulated in liposomes composed of different
Melia Karakose et al.
Archives of endocrinology and metabolism, 59(1), 42-46 (2015-05-01)
Patients with incidental nonfunctioning adrenal adenoma are associated with increased risk of obesity, impaired glucose tolerance and dyslipidemia. We aimed to investigate the relationship between thyroid function, serum lipids and insulin resistance in patients with nonfunctioning adrenal incidentaloma. Forty patients
Kohsuke Shakushiro et al.
Pharmaceutical research, 32(1), 238-247 (2014-07-19)
Sepantronium bromide (YM155) is administered by 168-hour continuous infusions in clinical studies due to its time-dependent pharmacological efficacy and rapid elimination from plasma. To enable more convenient administration, i.e., bolus injections with low frequency, we prepared liposomal formulations of YM155
Ratchada Cressey et al.
Indian journal of experimental biology, 52(12), 1173-1181 (2015-02-06)
In this study, we explored the effects of consumption of banana in thirty hypercholesterolemic and fifteen type 2 diabetic subjects. They were given a daily dose of 250 or 500 grams of banana for breakfast for 12 weeks. Fasting serum
Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells.
Yanuar Dwi Putra Limasale et al.
International journal of pharmaceutics, 479(2), 364-373 (2015-01-18)
Cyclooxygenase-2 (COX-2) is highly expressed in many different cancers. Therefore, the inhibition of the COX-2 pathway by a selective COX-2 inhibitor, celecoxib (CLX), may be an alternative strategy for cancer prevention and therapy. Liposomal drug delivery systems can be used
Chih-Wei Chang et al.
BMC complementary and alternative medicine, 15, 269-269 (2015-08-13)
Dyslipidaemia is highly associated with cardiovascular and cerebrovascular diseases, which have been ranked second and third place of leading causes of death in Taiwan. Some plant extracts have been proved effective against dyslipidaemia. However, the combination of plant extracts was
M Gomez-Mendoza et al.
Organic & biomolecular chemistry, 12(42), 8499-8504 (2014-09-19)
The aim of the present work is to develop two-channel emitters to probe local hydrophobicity by means of fluorescence quenching within different biomimetic supramolecular environments. To achieve this goal, the dansyl (Dns) and tryptophan (Trp) fluorophores have been covalently attached
Qian Ma et al.
Molecular pharmaceutics, 12(3), 665-674 (2015-01-15)
Probucol (PB), an antioxidant drug, is commonly used as a lipid concentration lowering drug to reduce blood plasma cholesterol levels in the clinic. However, the therapeutic effects of this drug are negatively impacted by its poor water solubility and low
Diana M Shih et al.
Journal of lipid research, 56(1), 22-37 (2014-11-08)
We performed silencing and overexpression studies of flavin containing monooxygenase (FMO) 3 in hyperlipidemic mouse models to examine its effects on trimethylamine N-oxide (TMAO) levels and atherosclerosis. Knockdown of hepatic FMO3 in LDL receptor knockout mice using an antisense oligonucleotide
Patrick Drücker et al.
Biochemical and biophysical research communications, 453(1), 143-147 (2014-09-30)
The integrity of supported phospholipid bilayer membranes is of crucial importance for the investigation of lipid-protein interactions. Therefore we recorded the formation of supported membranes on SiO2 and mica by quartz crystal microbalance and controlled the integrity by atomic force
Jeroen H P M van der Velde et al.
International journal of environmental research and public health, 12(3), 2330-2343 (2015-02-26)
This cross-sectional study is one of the first to examine and compare the independent associations of objectively measured sedentary time, moderate to vigorous physical activity (MVPA) and fitness with cardio-metabolic risk factors. We studied 543 men and women (aged 18-49
Dariush Mohammadyani et al.
Free radical biology & medicine, 76, 53-60 (2014-08-12)
Lipid droplets (LDs) are ubiquitous and physiologically active organelles regulating storage and mobilization of lipids in response to metabolic demands. Among the constituent LD neutral lipids, such as triacylglycerols, cholesterol esters, and free fatty acids, oxidizable polyunsaturated molecular species may
Lenka Kielbergerová et al.
Translational stroke research, 6(5), 375-383 (2015-08-15)
Perceived quality of life (QoL) and psychological well-being represents an important target of secondary prevention practice in post-stroke patients. We aimed to identify the major covariates of impaired QoL in stable post-stroke patients and whether impaired QoL itself represents independent
S Gidwani et al.
Human reproduction (Oxford, England), 29(7), 1518-1525 (2014-05-21)
Is polycystic ovary syndrome (PCOS) associated with altered levels of pro-inflammatory high-density lipoproteins (HDL) and activity of HDL-associated enzymes? In PCOS, HDL contained increased levels of the inflammatory marker serum amyloid A (SAA) and altered functioning of HDL-associated phospholipid transfer
S Riedel et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 78, 96-104 (2015-02-07)
Changes in lipid metabolism have been associated with tumor promotion in rat liver. Similarities and differences of lipid parameters were investigated using the mycotoxin fumonisin B1 (FB1) and the 2-acetylaminofluorene/partial hepatectomy (AAF/PH) treatments as cancer promoters in rat liver. A
Yannan Zhao et al.
Journal of lipid research, 55(10), 2053-2063 (2014-07-01)
We have observed that molecular constructs based on multiple apoA-I mimetic peptides attached to a branched scaffold display promising anti-atherosclerosis functions in vitro. Building on these promising results, we now describe chronic in vivo studies to assess anti-atherosclerotic efficacy of
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