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Showing 1-30 of 208 results for "C2674" within Papers
Carly A Hamilton et al.
Veterinary research, 49(1), 54-54 (2018-07-05)
Cattle are an economically important domestic animal species. In vitro 2D cultures of intestinal epithelial cells or epithelial cell lines have been widely used to study cell function and host-pathogen interactions in the bovine intestine. However, these cultures lack the
Nathalie Raffel et al.
PloS one, 14(4), e0215985-e0215985 (2019-04-30)
Reproductive tissue engineering (REPROTEN) has been recently defined as the application of the tissue engineering approach targeting reproductive organs and several research works are focusing on this novel strategy. Being still an innovative field, most of the scaffold characterization techniques
Bijan Abar et al.
Journal of biomedical materials research. Part A, 109(1), 54-63 (2020-05-18)
Despite advances in biomaterials research, there is no ideal device for replacing weight-bearing soft tissues like menisci or intervertebral discs due to poor integration with tissues and mechanical property mismatch. Designing an implant with a soft and porous tissue-contacting structure
Shenglan Wang et al.
The European journal of neuroscience, 53(6), 1691-1704 (2020-11-26)
Neural precursor cell-expressed developmentally downregulated protein 4-2 (Nedd4-2) is a member of the E3 ubiquitin ligase family that is highly expressed in sensory neurons and involved in pain modulation via downregulation of ion channels in excitable membranes. Ubiquitination involving Nedd4-2
J Hanoune et al.
The Journal of biological chemistry, 252(6), 2039-2045 (1977-03-25)
Treatment of rat liver plasma membranes with various commercial preparations of crude collagenase from Clostridium histolyticum at concentrations as low as 1 mug/ml, resulted in activation of the adenylate cyclase system. Maximal activation occurred at 50 to 100 mug/ml of
Marc N Faber et al.
Frontiers in cellular and infection microbiology, 12, 904606-904606 (2022-07-19)
Gastro-intestinal nematode (GIN) parasites are a major cause of production losses in grazing cattle, primarily through reduced growth rates in young animals. Control of these parasites relies heavily on anthelmintic drugs; however, with growing reports of resistance to currently available
Dylan J Meyer et al.
The Journal of general physiology, 152(12) (2020-11-25)
Tight regulation of the Na/K pump is essential for cellular function because this heteromeric protein builds and maintains the electrochemical gradients for Na+ and K+ that energize electrical signaling and secondary active transport. We studied the regulation of the ubiquitous
Cécile Boyer et al.
Frontiers in bioengineering and biotechnology, 8, 23-23 (2020-03-03)
Articular cartilage (AC) may be affected by many injuries including traumatic lesions that predispose to osteoarthritis. Currently there is no efficient cure for cartilage lesions. In that respect, new strategies for regenerating AC are contemplated with interest. In this context
Julika Pitsch et al.
Annals of neurology, 89(4), 666-685 (2020-12-29)
Limbic encephalitis (LE) comprises a spectrum of inflammatory changes in affected brain structures including the presence of autoantibodies and lymphoid cells. However, the potential of distinct lymphocyte subsets alone to elicit key clinicopathological sequelae of LE potentially inducing temporal lobe
Jiřina Hofmanová et al.
International journal of molecular sciences, 22(13) (2021-07-03)
The development of colon cancer, one of the most common malignancies, is accompanied with numerous lipid alterations. However, analyses of whole tumor samples may not always provide an accurate description of specific changes occurring directly in tumor epithelial cells. Here
Nathalie Chenais et al.
Experimental cell research, 335(1), 23-38 (2015-05-02)
The development of fin primary cell cultures for in vitro cellular and physiological studies is hampered by slow cell outgrowth, low proliferation rate, poor viability, and sparse cell characterization. Here, we investigated whether the recycling of fresh explants after a
Shufang Cai et al.
BMC biology, 21(1), 19-19 (2023-02-03)
Skeletal muscle development is a multistep process whose understanding is central in a broad range of fields and applications, from the potential medical value to human society, to its economic value associated with improvement of agricultural animals. Skeletal muscle initiates
Re: clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies: M. Gelbard, I. Goldstein, W. J. Hellstrom, C. G. McMahon, T. Smith, J. Tursi, N. Jones, G. J. Kaufman and C. C. Carson, III J Urol 2013; 190: 199-207.
S Jain et al.
The Journal of urology, 191(2), 561-563 (2013-11-19)
M D Bond et al.
Biochemistry, 23(13), 3085-3091 (1984-06-19)
The six collagenases (alpha, beta, gamma, delta, epsilon, and zeta) from Clostridium histolyticum isolated in the preceding paper [Bond, M. D., & Van Wart, H. E. (1984) Biochemistry (first paper of three in this issue)] have been characterized in detail.
Zhenhua Zhou et al.
Autophagy, 18(10), 2427-2442 (2022-02-24)
Intrauterine adhesions (IUA), characterized by endometrial fibrosis, is a common cause of uterine infertility. We previously demonstrated that partial epithelial-mesenchymal transition (EMT) and the loss of epithelial homeostasis play a vital role in the development of endometrial fibrosis. As a
Briana Ortiz et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 89(3), e13664-e13664 (2022-12-11)
During gestation, the decidua is an essential layer of the maternal-fetal interface, providing immune support and maintaining inflammatory homeostasis. Although Chlamydia (C.) trachomatis is associated with adverse pregnancy outcomes the pathogenic effects on maternal decidua contributing to adverse events are
Jian Guo et al.
Journal of immunology (Baltimore, Md. : 1950), 205(10), 2916-2925 (2020-09-30)
Tumor-associated macrophages (TAMs) play a critical role in the tumor inflammatory microenvironment and facilitate tumor growth and metastasis. Most types of tumors aberrantly express microRNAs (miRNAs), which can be transferred between cells by exosomes and can regulate gene expression in
Chen Liu et al.
Cell research, 31(10), 1106-1122 (2021-07-10)
Whereas the critical roles of innate lymphoid cells (ILCs) in adult are increasingly appreciated, their developmental hierarchy in early human fetus remains largely elusive. In this study, we sorted human hematopoietic stem/progenitor cells, lymphoid progenitors, putative ILC progenitor/precursors and mature
J R Merkel et al.
Biochemistry, 17(14), 2857-2863 (1978-07-11)
A true collagenase was isolated from the culture fluid of a marine bacterium which has been designated Vibrio B-30 (ATCC 21250). Collagenase production was obtained only in media containing collagen or certain degradation products of collagen. Partial purification on DEAE-cellulose
Roser Buscà et al.
BMC evolutionary biology, 15, 179-179 (2015-09-04)
The Ras/Raf/MEK/ERK signaling pathway is involved in essential cell processes and it is abnormally activated in ~30 % of cancers and cognitive disorders. Two ERK isoforms have been described, ERK1 and ERK2; ERK2 being regarded by many as essential due
Cynthia R Sides et al.
Journal of the American Society for Mass Spectrometry, 23(3), 505-519 (2011-12-31)
Pairing limited proteolysis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) to probe clostridial collagenase collagen binding domain (CBD) reveals the solution dynamics and stability of the protein, as these factors are crucial to CBD effectiveness as a
David J Machado et al.
Methods in molecular biology (Clifton, N.J.), 440, 297-313 (2008-03-29)
Single-cell amperometry is a powerful tool for the study of the mechanisms underlying secretion from cells that release electrochemically active substances like catecholamines, histamine, or serotonin. Amperometry has changed our view of the secretory process and the quantal release phenomenon.
Chris Bainbridge et al.
Journal of plastic surgery and hand surgery, 46(3-4), 177-183 (2012-06-08)
Collagenase Clostridium histolyticum (CCH) is a non-surgical, efficacious therapy for Dupuytren's contracture (DC). This study evaluated the efficacy and safety of CCH in patients with previous DC surgery. Data from 12 CCH clinical trials were pooled. At screening, patients provided
Tsung-Lin Yang et al.
Biomaterials, 66, 29-40 (2015-07-21)
Tissue structure is important for inherent physiological function and should be recapitulated during tissue engineering for regenerative purposes. The salivary gland is a branched organ that is responsible for saliva secretion and regulation. The salivary glands develop from epithelial-mesenchymal interactions
Reply by authors.
The Journal of urology, 191(2), 562-563 (2013-11-19)
Maslin Osathanunkul et al.
Analytical biochemistry, 433(2), 168-170 (2012-10-18)
Coomassie brilliant blue (CBB) heated by microwave was used as a staining dye for measuring gelatinolytic activity. The quantity of gelatin remaining after incubation with bacterial collagenase was determined using the heated CBB, resulting in visible blue pellets. Dimethyl sulfoxide
Gongyan Liu et al.
Tissue & cell, 65, 101348-101348 (2020-08-05)
Dermal papilla cells (DPCs) is the key dermal component of the hair follicle that directly regulates hair follicle development, growth and regeneration. Successfully isolated and cultured DPCs of Rex rabbit could provide a good model for the study of hair
Yulia Shwartz et al.
Cell, 182(3), 578-593 (2020-07-18)
Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pili muscle (APM), and the sympathetic nerve, providing a model to study interactions across epithelium, mesenchyme, and nerves. Here, we show that APMs and sympathetic nerves form a dual-component
Jörg Witthaut et al.
Clinical drug investigation, 31(11), 791-798 (2011-10-05)
Injectable collagenase Clostridium histolyticum is efficacious in correcting Dupuytren's contracture as assessed by changes in the angle of contracture and range of motion (ROM). However, clinically important changes in ROM have not been evaluated in depth. The objective of this
Irina Yu Zhuravleva et al.
Materials science & engineering. C, Materials for biological applications, 118, 111473-111473 (2020-12-02)
Bioprosthetic heart valves made from bovine pericardium (BP) and porcine pericardium (PP) preserved with glutaraldehyde (GA) are commonly used in valve surgeries but prone to calcification in many patients. In this study, we compared BP and PP preserved with GA
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