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Showing 1-30 of 255 results for "C9008" within Papers
Ji Sang Hwang et al.
Bioorganic & medicinal chemistry letters, 22(1), 706-708 (2011-11-15)
The activity-guided fractionation of the MeOH extract of the rhizomes and roots of Nardostachys chinensis led to the isolation of two new sesquiterpenoids, narchinol B (8) and narchinol C (9), along with 10 known compounds, ursolic acid (1), nardosinone (2)
Akram Astani et al.
Phytotherapy research : PTR, 28(10), 1547-1552 (2014-05-13)
Medicinal plants are increasingly of interest as novel source of drugs for antiherpetic agents, because herpes simplex virus (HSV) might develop resistance to commonly used antiviral drugs. An aqueous extract of Melissa officinalis and the phenolic compounds caffeic acid, p-coumaric
Kathrin Hacker et al.
Scientific reports, 9(1), 7901-7901 (2019-05-28)
Tripartite motif protein 52 (TRIM52) is a non-canonical TRIM family member harbouring the largest RING domain encoded in the human genome. In humans TRIM52 is conserved and has been under positive selection pressure, yet it has been lost in many
Frantisek Jursky et al.
European journal of pharmacology, 765, 1-6 (2015-08-15)
We previously identified cysteine 475 as a key residue for the inhibitory action of sanguinarine on the human glycine transporter GlyT1c. To define potential benzophenanthridine binding pocket more closely, we created a structural homology model of GlyT1 and also mutated
Burcu Bekdeşer et al.
Journal of agricultural and food chemistry, 62(46), 11109-11115 (2014-11-05)
Hypochlorous acid (HOCl) is an important reactive oxygen species (ROS) and non-radical and is taking part in physiological processes concerned with the defense of the organism, but there has been limited information regarding its scavenging by polyphenols. This study was
Janique Vandal et al.
Pharmaceutical biology, 53(6), 800-806 (2015-02-24)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MDR
Rachel R Schendel et al.
Carbohydrate research, 407, 16-25 (2015-02-24)
In comparison to the annual grain crops dominating current agricultural production, perennial grain species require fewer chemical and energy inputs and improve soil health and erosion control. The possibility for producing sustainable grain harvests from marginal land areas is motivating
Somsak Phattarasukol et al.
Applied and environmental microbiology, 78(19), 6812-6818 (2012-07-17)
High-throughput sequencing of cDNA prepared from RNA, an approach known as RNA-seq, is coming into increasing use as a method for transcriptome analysis. Despite its many advantages, widespread adoption of the technique has been hampered by a lack of easy-to-use
Eva Ramírez et al.
Journal of agricultural and food chemistry, 62(39), 9569-9575 (2014-09-12)
The main Spanish table olive varieties supplied by different olive cooperatives were investigated for their polyphenol compositions and the endogenous enzymes involved in their transformations during two growing seasons. Olives of the Manzanilla variety had the highest concentration in total
Ji-Eun Lee et al.
Pesticide biochemistry and physiology, 168, 104644-104644 (2020-07-28)
To find new and safe type of control agents against phytopathogenic fungi, the fumigant antifungal activity of 10 plant essential oils and constituents identified in cinnamon bark (Cinnamomum verum) and lemongrass (Cymbopogon citratus) essential oils was investigated against two phytopathogenic
Michel Schroyen et al.
Bioresource technology, 192, 696-702 (2015-06-22)
Pretreatment of lignocellulosic biomass is necessary to enhance the hydrolysis, which is the rate-limiting step in biogas production. Laccase and versatile peroxidase are enzymes known to degrade lignin. Therefore, the impact of enzymatic pretreatment was studied on a variety of
Raphael Serruya et al.
Heliyon, 7(9), e07888-e07888 (2021-09-16)
Hair loss and predominantly female hair loss is a common dermatologic condition with serious psychosocial consequences. Effective treatments remain scarce mainly due to the multifactorial elements involved in the onset of this chronic condition. The approved drugs available are based
Sarah E Bloch et al.
Chembiochem : a European journal of chemical biology, 15(16), 2393-2401 (2014-09-11)
Hydroxycinnamic acid esters (HCEs) are widely-distributed phenylpropanoid-derived plant natural products. Rosmarinic acid (RA), the most well-known HCE, shows promise as a treatment for cancer and neurological disorders. In contrast to extraction from plant material or plant cell culture, microbial production
Li Zhen Zhang et al.
Food chemistry, 174, 495-501 (2014-12-23)
Commonly consumed foxtail millet varieties Jingu28 and Jingu34 were compared in terms of phytochemical composition, antioxidant property, and antiproliferative activity. The cellular antioxidant activity (CAA) was evaluated based on HepG2 cell cultivation. Antiproliferative properties against HepG2 and MDA cell were
Longhai Dai et al.
Plant & cell physiology, 56(6), 1172-1182 (2015-03-12)
Mogrosides, the major bioactive components isolated from the fruits of Siraitia grosvenorii, are a family of cucurbitane-type tetracyclic triterpenoid saponins that are used worldwide as high-potency sweeteners and possess a variety of notable pharmacological activities. Mogrosides are synthesized from 2,3-oxidosqualene
p-Coumaric acid kills bacteria through dual damage mechanisms.
Zaixiang L, et al.
Food Control, 25, 550-554 (2012)
Serge Haan et al.
JAK-STAT, 4(1), e1062596-e1062596 (2015-09-29)
Aberrant activation of oncogenic kinases is frequently observed in human cancers, but the underlying mechanism and resulting effects on global signaling are incompletely understood. Here, we demonstrate that the oncogenic FIP1L1-PDGFRα kinase exhibits a significantly different signaling pattern compared to
Xue Han et al.
Molecular nutrition & food research, 64(10), e2000149-e2000149 (2020-04-06)
Although the physiological function of grape extract (GE) has long been recognized, the precise mechanism remains obscure. This study is designed to investigate the effects of GE on metabolism and the association between GE activation of brown adipose tissue (BAT)
Hassiba Aoudia et al.
Journal of agricultural and food chemistry, 60(47), 11675-11680 (2012-11-10)
In the present study, evaluated was the paralysis activity of whole Italian and Algerian Melia azedarach, commonly known as chinaberry, fruits and parts (seeds, wood, and kernels) against Meloidogyne incognita second stage juveniles (J(2)). The paralysis activity was evaluated in
Alejandro Cáceres-Mella et al.
Journal of agricultural and food chemistry, 62(29), 7255-7262 (2014-07-02)
The chemical and sensory effects of storing Sauvignon Blanc in colored bottles and exposing them to artificial light were examined. The colors of the bottles chosen were Dead Leaf Green, Antique Green, Amber, and Flint. The light was provided by
María Eugenia Goya et al.
Cell reports, 30(2), 367-380 (2020-01-16)
Recent discoveries have implicated the gut microbiome in the progression and severity of Parkinson's disease; however, how gut bacteria affect such neurodegenerative disorders remains unclear. Here, we report that the Bacillus subtilis probiotic strain PXN21 inhibits α-synuclein aggregation and clears
Ning Xu et al.
Frontiers in pharmacology, 8, 853-853 (2017-12-13)
Cerebral venous thrombosis (CVT) often causes human depression, whereas depression-induced low immunity makes the patients susceptible to gastrointestinal infection. Blueberry possesses antidepressant properties which may improve autoimmunity and reduce gastrointestinal infection. Brain-derived neurotrophic factor (BDNF) performs antidepressant function and can
Sindhu Mathew et al.
Journal of food science and technology, 52(9), 5790-5798 (2015-09-08)
The free radical scavenging activity and reducing power of 16 phenolic compounds including four hydroxycinnamic acid derivatives namely ferulic acid, caffeic acid, sinapic acid and p-coumaric acid, benzoic acid and its derivatives namely protocatechuic acid, gallic acid and vanillic acid
Pradeep Kumar Panda et al.
Carbohydrate polymers, 257, 117633-117633 (2021-02-06)
Shape memory polymer (SMP), composites and blends need to be prepared to improve the properties or obtain new functions of SMPs. In this work, we successfully prepared p-coumaric acid-modified water-soluble chitosan (M-Cs) and poly (vinyl alcohol) blended membrane (PVA/M-Cs) by
Hisanori Hattori et al.
Bioorganic & medicinal chemistry, 19(18), 5392-5401 (2011-08-26)
The tumor microenvironment is characterized by hypoxia, low-nutrient levels, and acidosis. A natural product chemistry-based approach was used to discover small molecules that modulate adaptive responses to a hypoxic microenvironment through the hypoxia-inducible factor (HIF)-1 signaling pathways. Five compounds, such
Hsi-Chuan Chen et al.
Plant physiology, 161(3), 1501-1516 (2013-01-25)
4-Coumaric acid:coenzyme A ligase (4CL) is involved in monolignol biosynthesis for lignification in plant cell walls. It ligates coenzyme A (CoA) with hydroxycinnamic acids, such as 4-coumaric and caffeic acids, into hydroxycinnamoyl-CoA thioesters. The ligation ensures the activated state of
Gulcin Tezcan et al.
Cellular and molecular neurobiology, 35(2), 175-187 (2014-09-13)
Glioblastoma multiforme (GBM) is one of the deadliest human malignancies. A cure for GBM remains elusive, and the overall survival time is less than 1 year. Thus, the development of more efficient therapeutic approaches for the treatment of these patients
Pasquale Filannino et al.
Applied and environmental microbiology, 80(24), 7574-7582 (2014-09-28)
The metabolism of hydroxycinnamic acids by strictly heterofermentative lactic acid bacteria (19 strains) was investigated as a potential alternative energy route. Lactobacillus curvatus PE5 was the most tolerant to hydroxycinnamic acids, followed by strains of Weissella spp., Lactobacillus brevis, Lactobacillus
Nazli Keskin et al.
Molecular and cellular biology, 35(10), 1741-1753 (2015-03-11)
Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription factor PATZ1 (MAZR), previously known for its transcriptional suppressor
Inês M Valente et al.
Food research international (Ottawa, Ont.), 116, 888-896 (2019-02-06)
For the first time, seven European varieties of Vicia faba L. seeds were investigated for (1) their phytonutrients profile by HPLC-DAD-MS/MS, (2) total phenolic content (TPC), and (3) antioxidant capacity (DPPH and FRAP assays). A wide range of compounds were
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