C9473

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Showing 1-6 of 6 results for "C9473" within Papers

The role of complement in immunological demyelination of the mammalian spinal cord.

J K Dyer et al.

Spinal cord, 43(7), 417-425 (2005-05-18)

Specificity of serum complement component to elicit immunological demyelination. To assess the role of complement components and pathways in experimental immunological demyelination of the adult rat spinal cord. ICORD, University of British Columbia, Vancouver, Canada. We used 32 adult male

Overview of complement activation and regulation.

Marina Noris et al.

Seminars in nephrology, 33(6), 479-492 (2013-10-29)

Complement is an important component of the innate immune system that is crucial for defense from microbial infections and for clearance of immune complexes and injured cells. In normal conditions complement is tightly controlled by a number of fluid-phase and

Complement System Part I - Molecular Mechanisms of Activation and Regulation.

Nicolas S Merle et al.

Frontiers in immunology, 6, 262-262 (2015-06-18)

Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in recognition molecular complexes upon sensing danger signals. The subsequent cascade of

The serum complement system: a simplified laboratory exercise to measure the activity of an important component of the immune system.

Jordan E Inglis et al.

Advances in physiology education, 32(4), 317-321 (2008-12-03)

The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that

Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.

P J Francis et al.

Journal of medical genetics, 46(5), 300-307 (2008-11-19)

Age related macular degeneration (AMD) is a leading cause of blindness. AMD is a complex disorder caused by genetic and environmental factors in which single nucleotide polymorphisms (SNPs) in the genes CFH and LOC387715/HTRA1/ARMS2 have prognostic importance for progression to

Risk Alleles in CFH and ARMS2 Are Independently Associated with Systemic Complement Activation in Age-related Macular Degeneration.

Smailhodzic D., et al.

Ophthalmology (2011)

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