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Showing 1-30 of 5504 results for "cn34891" within Papers
Chuang Liu et al.
Scientific reports, 5, 17269-17269 (2015-11-27)
The shells of pearl oysters, Pinctada fucata, are composed of calcite and aragonite and possess remarkable mechanical properties. These shells are formed under the regulation of macromolecules, especially shell matrix proteins (SMPs). Identification of diverse SMPs will lay a foundation
Yang Ni et al.
Journal of pharmaceutical and biomedical analysis, 107, 444-449 (2015-02-11)
A new method for simultaneous determination of phentermine and topiramate by liquid chromatography/electrospray tandem mass spectrometry (LC/MS/MS) operated in positive and negative ionization switching modes was developed and validated. Protein precipitation with acetonitrile was selected for sample preparation. Analyses were
Mickael Doué et al.
Analytical and bioanalytical chemistry, 407(15), 4473-4484 (2015-03-05)
Profiling conjugated urinary steroids to detect anabolic-steroid misuse is recognized as an efficient analytical strategy in both chemical-food-safety and anti-doping fields. The relevance and robustness of such profiling rely on the analysis of glucuronide and sulfate steroids, which is expected
Xuezhi Yang et al.
Xenobiotica; the fate of foreign compounds in biological systems, 44(11), 1009-1013 (2014-05-17)
1. Entinostat, also known as SNDX-275 or MS-275, is a novel, potent, orally bioavailable, class I selective histone deacetylase inhibitor. Pre-clinical data has show that MS-275 can enhance the activity of lapatinib in HER(2+) metastatic inflammatory and non-inflammatory breast cancer. This
Mirko Peitzsch et al.
The Journal of steroid biochemistry and molecular biology, 145, 75-84 (2014-10-15)
Steroid profiling for diagnosis of endocrine disorders featuring disordered production of steroid hormones is now possible from advances in liquid chromatography with tandem mass spectrometry (LC-MS/MS). Adrenal venous (AV) measurements of aldosterone and cortisol are a standard practice in the
Ming-Qiang Zheng et al.
Nuclear medicine and biology, 42(6), 578-584 (2015-03-18)
The PET radiotracer [(18)F]FMISO has been used in the clinic to image hypoxia in tumors. The aim of the present study was to optimize the radiochemical parameters for the preparation of [(18)F]FMISO using a microfluidic reaction system. The main parameters
Sameh Magdeldin et al.
Journal of proteome research, 14(2), 943-952 (2014-11-16)
The purpose of this study is to determine the behavioral and proteomic consequences of shock-induced stress in zebrafish (Danio rerio) as a vertebrate model. Here we describe the behavioral effects of exposure to predictable and unpredictable electric shock, together with
Christie Hollingdale et al.
Analytical and bioanalytical chemistry, 407(18), 5353-5363 (2015-05-02)
The worldwide increase in cyanobacterial contamination of freshwater lakes and rivers is of great concern as many cyanobacteria produce potent hepatotoxins and neurotoxins (cyanotoxins). Such toxins pose a threat to aquatic ecosystems, livestock, and drinking water supplies. In addition, dietary
Scott A Robotham et al.
Journal of the American Society for Mass Spectrometry, 26(9), 1570-1579 (2015-07-01)
In an effort to better characterize the fragmentation pathways promoted by ultraviolet photoexcitation in comparison to collision induced dissociation (CID), six adrenocorticotropic hormone (ACTH) peptides in a range of charge states were subjected to 266 nm ultraviolet photodissociation (UVPD), 193
S Huber et al.
Journal of pharmaceutical and biomedical analysis, 104, 137-143 (2014-12-17)
Esters of the cytostatic bendamustine (1), previously demonstrated to be much more potent than the parent compound as antiproliferative agents in vitro, were investigated for stability in buffer and plasma, as well as against porcine liver esterase in the presence
Xing Jin et al.
Oncotarget, 5(6), 1635-1645 (2014-04-12)
Bladder cancer (BC) is a common cancer but diagnostic modalities, such as cystoscopy and urinary cytology, have limitations. Here, high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (HPLC-QTOFMS) was used to profile urine metabolites of 138 patients with BC and 121 control
Shupeng Yang et al.
Journal of pharmaceutical and biomedical analysis, 110, 1-11 (2015-03-24)
Lappaconitine (LAP), a non-addictive potent analgesic drug, is broadly used to treat cancer and postoperative pain in many countries, and it also has antibiotic activity against Pseudomonas aeruginosa and Salmonella Typhi. Despite its widespread usage and potential for expanded use
Patricia Morales et al.
Food chemistry, 185, 289-297 (2015-05-09)
There is a lack of information on the potential use of xoconostle cultivars as sources of antioxidants for food, pharmaceutical and colorant industries. The aim of this study was to provide a phytochemical characterisation and antioxidant activity evaluation of Opuntia
Naoko Iwata-Yoshikawa et al.
Journal of virology, 88(15), 8597-8614 (2014-05-23)
Severe acute respiratory syndrome-related coronavirus (SARS-CoV) is an emerging pathogen that causes severe respiratory illness. Whole UV-inactivated SARS-CoV (UV-V), bearing multiple epitopes and proteins, is a candidate vaccine against this virus. However, whole inactivated SARS vaccine that includes nucleocapsid protein
Benjamin E W Toh et al.
Journal of microbiological methods, 118, 128-132 (2015-09-19)
Acinetobacter baumannii, one of the more clinically relevant species in the Acinetobacter genus is well known to be multi-drug resistant and associated with bacteremia, urinary tract infection, pneumonia, wound infection and meningitis. However, it cannot be differentiated from closely related
Qian Zhao et al.
Environmental science & technology, 49(15), 9092-9099 (2015-07-03)
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) are of great concern due to their higher toxicity compared to PBDEs. However, the abiologic process whereby PBDEs are converted to OH-PBDEs in the aquatic environment is not well understood. To explore the possibility of
Guoyun Li et al.
Journal of chromatography. A, 1397, 43-51 (2015-04-29)
Pneumococcal type-3 polysaccharide (Pn3P) is considered a major target for the development of a human vaccine to protect against Streptococcus pneumoniae infection. Thus, it is critical to develop methods for the preparation and analysis of Pn3P-derived oligosaccharides to better understand
Sara Triñanes et al.
Talanta, 132, 433-442 (2014-12-06)
A new straightforward and inexpensive sample screening method for both EPA and EU priority polycyclic aromatic hydrocarbons (PAHs) in water has been developed. The method is based on combined direct immersion and headspace (DIHS) sorptive extraction, using low-cost disposable material
Yi Dong et al.
Food chemistry, 168, 538-545 (2014-08-31)
The kinetics of adsorption and desorption behaviours of five macroporous resins for enriching flavonoids from Glycyrrhizaglabra L. leaf were investigated. All five resins showed similar and effective adsorption and desorption properties. A pseudo-second-order kinetics model was suitable for evaluating the
Daisuke Sugahara et al.
Proteomics, 15(17), 2921-2933 (2015-04-30)
One of the promising approaches to the development of cancer diagnostic systems is quantification of a specific protein carrying cancerous glycans. Potential utility of Wisteria floribunda agglutinin (WFA) for such assays has been suggested for several cancer types. To develop
Masahiko Isaka et al.
The Journal of antibiotics, 68(5), 334-338 (2014-11-20)
Two new hydroanthraquinones, paradictyoarthrins A (1) and B (2), were isolated from the mangrove-derived fungus Paradictyoarthrinium diffractum BCC 8704. Structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The absolute configuration of
J J Baeza-Baeza et al.
Journal of chromatography. A, 1284, 28-35 (2013-03-05)
The optimisation of the experimental conditions in gradient reversed-phase liquid chromatography requires reliable algorithms for the description of the retention and peak profile. As in isocratic elution, the linear relationship between the logarithm of the retention factor and the solvent
Masafumi Sakono et al.
Biochimica et biophysica acta, 1840(9), 2904-2913 (2014-04-29)
Testis-specific chaperone calmegin is required for the generation of normal spermatozoa. Calmegin is known to be a homologue of endoplasmic reticulum (ER) residing lectin chaperone calnexin. Although functional similarity between calnexin and calmegin has been predicted, detailed information concerned with
Haoyue Zhang et al.
Molecular genetics and metabolism, 114(2), 123-128 (2014-12-03)
Mucopolysaccharidoses (MPS) are complex storage disorders that result in the accumulation of glycosaminoglycans (GAGs) in urine, blood, brain and other tissues. Symptomatic patients are typically screened for MPS by analysis of GAG in urine. Current screening methods used in clinical
Sherif B Abdel Ghani et al.
Food chemistry, 194, 516-521 (2015-10-17)
QuEChERS method combined with GC-IT-MS was developed and validated for the determination of chlorfenapyr residues in squash and okra matrices. Method accuracy, repeatability, linearity and specificity were investigated. Matrix effect was discussed. Determination coefficients (R(2)) were 0.9992 and 0.9987 in
Charles J Mason et al.
Journal of chemical ecology, 41(1), 75-84 (2014-12-06)
Microbial symbionts are becoming increasingly recognized as mediators of many aspects of plant - herbivore interactions. However, the influence of plant chemical defenses on gut associates of insect herbivores is less well understood. We used gypsy moth (Lymantria dispar L.)
Eun Ji Chung et al.
Advanced healthcare materials, 4(3), 367-376 (2014-08-27)
Atherosclerosis is a multifactorial inflammatory disease that can progress silently for decades and result in myocardial infarction, stroke, and death. Diagnostic imaging technologies have made great strides to define the degree of atherosclerotic plaque burden through the severity of arterial
Isabel Sospedra et al.
Journal of food science, 80(6), H1425-H1431 (2015-05-16)
Obesity prevalence in developed countries has promoted the need to identify the mechanisms involved in control of feeding and energy balance. We have tested the hypothesis that different fats present in diet composition may contribute in body weight gain and
Mette Thing et al.
Journal of pharmaceutical sciences, 103(12), 4021-4029 (2014-10-31)
Long-acting nonsteroidal anti-inflammatory drug formulations for intra-articular injection might be effective in the management of joint pain and inflammation associated sports injuries and osteoarthritis. In this study, a prodrug-based delivery system was evaluated. The synthesized diclofenac ester prodrug, a weak
Li Ren et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 959, 16-21 (2014-04-22)
A liquid chromatography-electrospray ionization tandem mass spectrometry method was established and validated for the determination of bevantolol in human plasma using propranolol as the internal standard. The optimal chromatographic behavior of bevantolol and propranolol was achieved on a Welch Ultimate
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