Iván Devesa-Guerra et al.
Journal of molecular biology, 432(7), 2204-2216 (2020-02-23)
Tools for actively targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epigenetic modification. DNA demethylation in mammals involves TET-mediated oxidation of 5-methylcytosine (5-meC), which may promote its replication-dependent dilution and/or active