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Showing 1-30 of 38 results for "D2016" within Papers
P Shen et al.
The Journal of nutrition, 136(4), 899-905 (2006-03-22)
Compounds that target the peroxisome proliferator-activated receptors PPARalpha and PPARgamma are used to correct dyslipidemia and to restore glycemic balance, respectively. Because the majority of diabetic patients suffer from atherogenic lipid abnormalities, in addition to insulin resistance, ligands are required
Longxin Qiu et al.
Molecular medicine reports, 5(1), 217-222 (2011-09-29)
The role of peroxisome proliferator-activated receptors (PPARs) as anti-inflammatory mediators has been established, and the fact that some isoflavones are dual agonists of PPARα/γ indicates the involvement of PPARα and/or PPARγ in the anti-inflammatory action of certain isoflavones. However, the
Isabelle A Kagan et al.
Natural product communications, 7(12), 1605-1608 (2013-02-19)
Red clover (Trifolium pratense) is rich in phenolic compounds. Both the crude phenolic extract and biochanin A, an isoflavonoid component of the extract, suppress growth of Clostridium sticklandii, a bovine, Gram-positive, ruminal hyper-ammonia producing bacterium (HAB). The purpose of this
Huabo Wei et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2530-2534 (2012-01-20)
To establish a highly sensitive screening method for phytoestrogen active constituents and to primarily screen the phytoestrogenic active constituents from the chickpea extractions by the method. Human ERalpha cDNA was cloned using MCF-7 total RNA as the template by RT-PCR
Shilpa Puli et al.
Journal of neuro-oncology, 79(2), 135-142 (2006-04-07)
Glioblastoma multiforme is a primary brain tumor associated with extensive invasion into surrounding brain tissue. Matrix metalloproteinases (MMPs) and urokinase plasminogen activation (uPA) system are shown to be involved in tumor invasion as they help in degradation of extracellular matrix
Mi Ja Chung et al.
Life sciences, 93(9-11), 401-408 (2013-08-03)
Anti-allergic effects and action mechanism of phloretin (Phl) and biochanin A (BioA) on the IgE-antigen complex-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells were investigated. Cell viability, formation of reactive oxygen species (ROS), DPPH radical-scavenging activity, β-hexosaminidase release, production
Ling Zhang et al.
Biological trace element research, 146(3), 376-380 (2011-11-22)
To improve the nutritional value of chickpea food, selenium (Se)-rich chickpea sprouts were produced by germination of chickpea seeds for 6 days at 28 centigrade in the presence of various concentrations of Na(2)SeO(3) in germination solution. High concentrations of selenite
Dalia Somjen et al.
The Journal of steroid biochemistry and molecular biology, 135, 67-70 (2013-01-22)
The use of anticoagulants has been associated with systemic osteoporosis and increased risk for poor fracture healing but is inevitable following major orthopedic surgery of lower limbs. Rivaroxaban A (R) is an anticoagulant recently introduced in the clinical setting, which
Longxin Qiu et al.
Phytotherapy research : PTR, 26(6), 860-864 (2011-11-16)
The effects of red clover extract and its bioactive components, biochanin A and formononetin, on the blood glucose and lipid levels of streptozotocin (STZ) induced-diabetic mice were investigated. Male diabetic C57BL/6 mice were induced by multiple low-dose STZ administration and
Satu-Maarit Heinonen et al.
Journal of agricultural and food chemistry, 52(22), 6802-6809 (2004-10-28)
Dietary supplements manufactured from red clover are widely marketed to provide the beneficial health effects of isoflavones without changing the original diet. In this study the metabolism of formononetin and biochanin A, the principal isoflavones of red clover, was studied
Evelyne Reiter et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 27(12), 1037-1042 (2011-08-02)
Isoflavones from red clover and soy plant extracts are used in highly concentrated food supplements as an alternative to hormone replacement therapy. Due to their estrogenic activity, isoflavones are a focus of safety concerns about their potential to promote the
Hyo-Kyung Han et al.
Die Pharmazie, 66(9), 710-715 (2011-10-27)
The present study aimed to improve the in vivo effectiveness of biochanin A as a P-gp inhibitor by formulation in solid dispersion (SD). SDs were prepared with Solutol HS15 and hydroxypropylmethyl cellulose (HPMC2910) and their inhibition effect on P-gp mediated
Interaction of isoflavones and endophyte-infected tall fescue seed extract on vasoactivity of bovine mesenteric vasculature
Jia Y, et al.
Frontiers in nutrition, 2(9), 32-32 (2015)
Combination of Biochanin A and Temozolomide Impairs Tumor Growth by Modulating Cell Metabolism in Glioblastoma Multiforme
Desai V, et al.
Anticancer research, 39(1), 57-66 (2019)
C M de Andrade et al.
Climacteric : the journal of the International Menopause Society, 15(2), 186-194 (2011-11-10)
The risks of hormone replacement therapy have led to a search for new alternatives such as phytoestrogens, plant compounds with estrogen-like biological activity. Isoflavones are the phytoestrogens most extensively studied and can be found in soybean, red clover and other
Muhammad Arman
Natural product research, 25(14), 1352-1360 (2011-08-24)
A simple extraction procedure and HPLC method was developed to analyse the major and minor components of induced phytoalexins of elicited tissues (seeds) of chickpeas (Cicer arietinum L.) and peas (Pisum sativum L.) treated with a biotic elicitor (k-carrageenan) of
Patchima Sithisarn et al.
Antiviral research, 97(1), 41-48 (2012-10-27)
From a panel of 22 flavonoids, we identified six compounds (apigenin, baicalein, biochanin A, kaempferol, luteolin, naringenin) that inhibited influenza A nucleoprotein production in human lung epithelial (A549) cells infected with the highly pathogenic avian influenza H5N1 virus strain A/Thailand/Kan-1/04
Ranganathan Harini et al.
European journal of pharmacology, 676(1-3), 89-94 (2011-12-20)
The study was designed to investigate the antihyperglycemic effect of biochanin A on streptozotocin-diabetic rats. Diabetes was induced in adult male albino rats of the Wistar strain, weighing 180-200 g, by administration of streptozotocin (40 mg/kg of body weight) intraperitoneally.
Ewelina Szliszka et al.
Urologic oncology, 31(3), 331-342 (2011-08-02)
Biochanin-A, a major dietary isoflavone in soy and red clover, possesses anticancer and chemopreventive properties. Induction of apoptosis by naturally occurring dietary agents is an important event for cancer chemoprevention. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis selectively in
Guohua An et al.
Biopharmaceutics & drug disposition, 32(8), 446-457 (2011-09-13)
The aim of the study was to investigate the role of breast cancer resistance protein (BCRP, ABCG2) in the transport of biochanin A and its metabolites. Transport studies were carried out in MDCK/bcrp1 as well as in control cells, and
Wim Vanden Berghe et al.
Cancer research, 66(9), 4852-4862 (2006-05-03)
We have analyzed in molecular detail how soy isoflavones (genistein, daidzein, and biochanin A) suppress nuclear factor-kappaB (NF-kappaB)-driven interleukin-6 (IL6) expression. In addition to its physiologic immune function as an acute stress cytokine, sustained elevated expression levels of IL6 promote
Estelle Loing et al.
Journal of cosmetic science, 64(1), 45-58 (2013-03-02)
Male pattern hair loss is a major cosmetic concern affecting both genders with a preference for men. Major causes of hair loss in genetically predisposed individuals include hormonal dysfunction, loss of extracellular matrix (ECM) proteins in the follicular bed, and
Ji Wei Tan et al.
Neurochemical research, 38(3), 512-518 (2012-12-12)
L-Glutamate plays a crucial role in neuronal cell death, which is known to be associated with various neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's diseases. In this study, we investigated the protective effects of biochanin A, a phytoestrogen compound
Ronald Maul et al.
The British journal of nutrition, 103(11), 1569-1572 (2010-01-14)
In addition to soya-derived preparations, red clover-based dietary supplements have gained considerable interest as an alternative isoflavone (IF) source. While metabolism and bioavailability of the main IF from both sources have already been investigated, studies are still lacking on the
Nikolas Fokialakis et al.
Bioorganic & medicinal chemistry, 20(9), 2962-2970 (2012-04-03)
Biochanin A (BCA), a major isoflavone in red clover and many other legumes, has been reported to display estrogenic as well as cancer chemopreventive properties. Ingested BCA is known to display low bioavailability due to poor solubility, extensive metabolism and
Ling Zhang et al.
Journal of dietary supplements, 9(1), 34-44 (2012-03-22)
Chickpea sprouts (CS) may become one of the natural products of high demand due to their nutritional values. The aim of this work was to study the enrichment of vanadium (V) during the germination of chickpea seeds in order to
Olga Leuner et al.
Journal of the science of food and agriculture, 93(3), 575-579 (2012-08-29)
Isoflavones and coumestrol from dietary legumes are plant constituents showing multiple beneficial effects on humans. Owing to their ability to bind with mammalian estrogenic receptors and thereby intervention in several kinds of hormone-related cancers, they have received much attention. Soybean
Ziyun Wu et al.
Journal of agricultural and food chemistry, 60(35), 8606-8615 (2012-07-24)
The effect of germination on bioactive components in legume seeds was investigated in terms of the antioxidant capacity and total phenolic contents. Germination increased the total phenolic content and antioxidant capacity of most seeds. Particularly in chickpea seeds, the isoflavone
Sunil Kumar Manna
Biochemical pharmacology, 83(10), 1383-1392 (2012-03-06)
Several protein tyrosine kinase (PTK) inhibitors predominantly isoflavones, such as genistein, erbstatin, quercetin, daidzein, present in red clover, cabbage and alfalfa, show apoptotic effect against cancer cells. In this study I found that biochanin, a methoxy form of genistein, inhibits
Tae-Gyu Lim et al.
Biochemical pharmacology, 86(7), 896-903 (2013-08-21)
Solar UV (sUV) is an important environmental carcinogen. Recent studies have shown that sUV is associated with numerous human skin disorders, such as wrinkle formation and inflammation. In this study, we found that the isoflavone, biochanin A, inhibited the expression
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