CN
Search Within
d7802
Applied Filters:
Keyword:'d7802'
Showing 1-30 of 163 results for "d7802" within Papers
Xun Zhang et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 52(7), 866-874 (2012-11-03)
Equol is the end metabolite of daidzein by certain intestinal bacteria, which has stronger bioactivity comparing with daidzein. To evaluate the role of orally administrated equol-producing bacterium on increasing equol production and shifting intestinal microbiota of embracer animal. In total
Agnes Emma Daruházi et al.
Journal of pharmaceutical and biomedical analysis, 84, 112-116 (2013-07-03)
Isoflavonoids are widespread constituents in medical plants especially in legumes (Fabaceae), but occur in other different plant families as well (Rosaceae, Iridaceae, Amaranthaceae). Their antioxidant, estrogen-like, anti-inflammatory and analgesic effects make them promising compounds in therapy of important disorders especially
Katherine A Jackman et al.
Current medicinal chemistry, 14(26), 2824-2830 (2007-11-30)
Isoflavones are an important class of phytoestrogens that are found at extrememly high levels in soy. Up until recently, daidzein and genistein were considered to be the most important and hence most studied isoflavones, however more recently attention has shifted
C O Cimino et al.
Clinica chimica acta; international journal of clinical chemistry, 287(1-2), 69-82 (1999-10-06)
Most methods for detecting isoflavones in biological samples do not measure the concentration of sulfate conjugates. An LC-MS method is reported here to estimate urinary concentrations of genistein and daidzein, their sulfate and glucuronide conjugates and other major metabolites. Human
Petra H M Peeters et al.
The Journal of nutrition, 137(5), 1294-1300 (2007-04-24)
Dietary phytoestrogens may play a role in chronic disease occurrence. The aim of our study was to assess the variability of plasma concentrations in European populations. We included 15 geographical regions in 9 European countries (Denmark, France, Germany, Greece, Italy
S S Masrudin et al.
Andrologia, 47(10), 1153-1159 (2015-01-21)
Pueraria mirifica (PM) extract contains phytoestrogen daidzein and genistein. In this study, we investigated the protective effect of PM extract, daidzein and genistein on a testosterone-induced prostatic hyperplasia in rats. Testosterone was administered at 3 mg kg(-1) to rats followed
T Berman et al.
Environment international, 59, 478-484 (2013-08-22)
The Ministry of Health Biomonitoring Study estimated exposure of individuals in the Israeli population to bisphenol A (BPA), organophosphate (OP) pesticides, phthalates, cotinine, polycyclic aromatic hydrocarbons (PAHs), and the phytoestrogenic compounds genistein and daidzein. In 2011, 250 individuals (ages 20-74)
S Heinonen et al.
Analytical biochemistry, 274(2), 211-219 (1999-10-21)
The metabolic products of daidzein and genistein, the principal isoflavones of soy, were examined. Six volunteers included soy into their normal diet for a 2-week period and urine samples were analyzed before and after soy consumption. Isolation and characterization of
Chengjun Yu et al.
Progress in neuro-psychopharmacology & biological psychiatry, 43, 157-167 (2012-12-27)
Daidzein is one of the most important isoflavones present in soy and it is unique as it can be further metabolized to equol, a compound with greater estrogenic activity than other isoflavones. The potential role of daidzein in the prevention
Jun-Seong Park et al.
Bioorganic & medicinal chemistry letters, 18(18), 5006-5009 (2008-08-30)
One new ortho-dihydroxyisoflavone, 7,3',4'-trihydroxyisoflavone (2), and two known ortho-dihydroxyisoflavone derivatives were isolated from 5-year-old Doenjang (Korean fermented soypaste), and evaluated as potent antioxidant by comparing with other known isoflavones. 7,8,4'-Trihydroxyisoflavone (1), 7,3',4'-trihydroxyisoflavone (2), and 6,7,4'-trihydroxyisoflavone (3) inhibited DPPH (Diphenyl-1-picryl hydrazyl)
Yu Qin et al.
The Journal of nutrition, 144(1), 49-54 (2013-11-15)
Daidzein (one of the major isoflavones) can be metabolized to equol in certain individuals. The effects of isoflavones alone and equol status on lipid profiles are still controversial. To evaluate the 6-mo effects of daidzein on cardiovascular risk factors in
Erik Ullerås et al.
Journal of applied toxicology : JAT, 28(8), 1045-1053 (2008-07-16)
The adrenal gland is a vulnerable target for toxic insult. Disruption of adrenal steroidogenesis and hormone secretion may cause serious effects on human health. A human in vitro model is needed to predict effects, and elucidate mechanisms of endocrine disruption
Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke.
Eunhee Kim et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(45), 15113-15126 (2015-11-13)
Stroke is the world's leading cause of physiological disability, but there are currently no available agents that can be delivered early after stroke to enhance recovery. Daidzein, a soy isoflavone, is a clinically approved agent that has a neuroprotective effect
Lea Bredsdorff et al.
The American journal of clinical nutrition, 98(1), 209-216 (2013-05-24)
Epidemiologic studies have suggested that a higher intake of flavonoids may be associated with lower risk of ischemic heart disease. However, the traditional estimation of flavonoid intake by using dietary assessment methods is affected by subjective measures. We examined whether
Yuanyang Guo et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 52(6), 696-702 (2012-09-01)
To screen and identify a bacterium capable of converting daidzein to S-equol. We used antibiotics to limit unrelated bacterial growth and enrich the target bacteria, and isolated the aim bacterial strain from rat intestine. The metabolite of daidzein was tested
Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer
Chan KKL, et al.
Cancer Cell International, 18(1), 65-65 (2018)
Ziming Shi et al.
European journal of drug metabolism and pharmacokinetics, 40(3), 255-266 (2014-05-03)
Tectorigenin (Te) is a main active component in the flowers of Pueraria thomsonii Benth. and the rhizomes of Belamcanda chinensis (L.) DC. Previously, we have reported the pharmacokinetic properties of Te in rat plasma. The purpose of this study was
Antioxidant activity of phytoestrogen type isoflavones in biomimetic environments
Voicescu M, et al.
New. J. Chem., 40(1), 606-612 (2016)
Dapeng Chen et al.
Pharmaceutical biology, 50(12), 1561-1566 (2012-09-18)
Daidzein is a naturally occurring compound and has various health benefits. However, its effects on intestinal smooth muscle contractility remain unknown. The present study was to characterize the effects of daidzein on the contractility of isolated jejunal smooth muscle and
Deniz Tasdemir et al.
Journal of medicinal chemistry, 49(11), 3345-3353 (2006-05-26)
After the discovery of a potent natural flavonoid glucoside as a potent inhibitor of FabI, a large flavonoid library was screened against three important enzymes (i.e., FabG, FabZ, and FabI) involved in the fatty acid biosynthesis of P. falciparum. Although
Aliya Ahmad et al.
Pharmaceutical biology, 53(5), 758-766 (2015-03-11)
Soybean and its fermented products are the most common source of isoflavones in human food. The present study quantifies the major glycosides and aglycones in soybean and its fermented product tempeh isoflavone extracts. The comparision of antioxidant effects and BACE1
Subhashree Parida et al.
The Journal of surgical research, 197(2), 363-373 (2015-04-25)
The aim of the present study was to assess the effect of seven days daidzein pretreatment in cecal ligation and puncture (CLP) model of sepsis. We assessed the survival benefit of daidzein and its effect on lung injury in CLP-induced
Marta Moskot et al.
Metabolic brain disease, 30(5), 1257-1267 (2015-07-26)
Natural flavonoids such as genistein, kaempferol and daidzein were previously found to be able to reduce efficiency of glycosaminoglycan synthesis in cells of patients suffering from mucopolysaccharidoses, inherited metabolic diseases with often brain disease symptoms. This feature was employed to
Thomas Clavel et al.
International journal of systematic and evolutionary microbiology, 60(Pt 7), 1527-1531 (2009-08-18)
The C3H/HeJBir mouse model of intestinal inflammation was used for isolation of a Gram-positive, rod-shaped, non-spore-forming bacterium (B7(T)) from caecal suspensions. On the basis of partial 16S rRNA gene sequence analysis, strain B7(T) was a member of the class Actinobacteria
Quan Jiang et al.
Journal of medicinal chemistry, 53(16), 6153-6163 (2010-07-31)
Daidzein (1) is a natural estrogenic isoflavone. We report here that 1 can be transformed into anti-estrogenic ligands by simple alkyl substitutions of the 7-hydroxyl hydrogen. To test the effect of such structural modifications on the hormonal activities of the
Di Xu et al.
Drug development and industrial pharmacy, 41(4), 552-559 (2014-02-06)
In this study, the in vivo oral absorption of a nanocrystal tablet formulation of a BCS II poorly water-soluble drug was compared with that of its water-soluble salt form. Silybin is used as the model drug, and its nanosuspension was
Kelly R Walsh et al.
The American journal of clinical nutrition, 85(4), 1050-1056 (2007-04-07)
Although soy isoflavonoids have a number of health-promoting benefits, information concerning the sites of their absorption and metabolism in humans remains limited. Isoflavonoid absorption from the gut requires deconjugation of glucosides to aglycones. The objective was to investigate the role
Nora E Gray et al.
Cancer prevention research (Philadelphia, Pa.), 2(2), 134-142 (2009-01-15)
Dehydroepiandrosterone (DHEA) is used as a dietary supplement and can be metabolized to androgens and/or estrogens in the prostate. We investigated the hypothesis that DHEA metabolism may be increased in a reactive prostate stroma environment in the presence of proinflammatory
Lin Li et al.
Nutrition and cancer, 65(3), 390-397 (2013-03-28)
To assess dietary isoflavone intake between population and hospital outpatient controls and examine if cancer risks estimated for isoflavone using hospital outpatient controls would be different from those using population controls. Three parallel case-control studies on leukemia, breast, and colorectal
Ka H Wong et al.
Journal of ethnopharmacology, 164, 53-63 (2015-01-07)
Puerariae Lobatae Radix (PLR) and Puerariae Thomsonii Radix (PTR) are traditional Chinese medicines used for the treatment of diabetes and cardiovascular diseases. These two herbs are used interchangeably in clinical practice, even though they possess significantly different chemical profiles. In
Page 1 of 6