D8147

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Showing 1-6 of 6 results for "D8147" within Papers

Structure-activity relationship studies of dynorphin A and related peptides.

T Naqvi et al.

Peptides, 19(7), 1277-1292 (1998-10-24)

An up-to-date review is presented covering all the available information concerning the isolation, discovery, synthesis, conformation, receptor binding characteristics, pharmacological properties and SAR studies of dynorphin A and related peptides. The potential of dynorphin A and its analogs has yet

Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors.

Esa R Korpi et al.

Addiction biology, 22(4), 1022-1035 (2016-03-19)

Opioid antagonist treatments reduce alcohol drinking in rodent models and in alcohol-dependent patients, with variable efficacy across different studies. These treatments may suffer from the development of tolerance and opioid receptor supersensitivity, as suggested by preclinical models showing activation of

The kappa opioid receptor and dynorphin co-localize in vasopressin magnocellular neurosecretory neurons in guinea-pig hypothalamus.

S J Shuster et al.

Neuroscience, 96(2), 373-383 (2000-02-23)

The relationship between the cloned kappa opioid receptor, dynorphin, and the neurohypophysial hormones vasopressin and oxytocin was analysed in the guinea-pig hypothalamic magnocellular neurosecretory neurons. This analysis was performed in order to understand better which population of neuroendocrine neurons in

Dynorphin A as a potential endogenous ligand for four members of the opioid receptor gene family.

S Zhang et al.

The Journal of pharmacology and experimental therapeutics, 286(1), 136-141 (1998-07-10)

Dynorphin A is an endogenous opioid peptide that activates the kappa opioid receptor (KOR) with high potency. Some studies also showed that the distribution and functional activity of dynorphin A are not completely correlated with those of KOR, suggesting that

Insights into the unique torpor of Botrylloides leachi, a colonial urochordate

Hyams Y, et al.

Developmental Biology, 428(1), 101-117 (2017)

Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture

Gross R A and Macdonald R L

Proceedings of the National Academy of Sciences of the USA, 84(15), 5469-5473 (1987)

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