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Showing 1-30 of 304 results for "D9026" within Papers
Taichi Yoshikata et al.
Applied and environmental microbiology, 80(23), 7142-7153 (2014-09-14)
Sphingobium sp. strain SYK-6 is able to assimilate lignin-derived biaryls, including a biphenyl compound, 5,5'-dehydrodivanillate (DDVA). Previously, ligXa (SLG_07770), which is similar to the gene encoding oxygenase components of Rieske-type nonheme iron aromatic-ring-hydroxylating oxygenases, was identified to be essential for
Harry H Matundan et al.
Journal of virology, 89(5), 2530-2542 (2014-12-17)
To investigate the role of the signal sequences of herpes simplex virus 1 (HSV-1) gK on virus replication and viral pathogenesis, we constructed recombinant viruses with or without mutations within the signal sequences of gK. These recombinant viruses expressed two
Menglin Ma et al.
Journal of bacteriology, 197(10), 1807-1818 (2015-03-18)
The accessory growth regulator (Agr)-like quorum sensing (QS) system of Clostridium perfringens controls the production of many toxins, including beta toxin (CPB). We previously showed (J. E. Vidal, M. Ma, J. Saputo, J. Garcia, F. A. Uzal, and B. A.
Hormonal regulation of steroid receptor coactivator-1 mRNA in the male and female green anole brain.
H N Kerver et al.
Journal of neuroendocrinology, 27(3), 223-233 (2015-01-06)
Green anole lizards are seasonal breeders, with male sexual behaviour primarily regulated by an annual increase in testosterone. Morphological, biochemical and behavioural changes associated with reproduction are activated by testosterone, generally with a greater effect in the breeding season (BS)
Immunological detection of glycoproteins on blots based on labeling with digoxigenin.
A Haselbeck et al.
Methods in molecular biology (Clifton, N.J.), 14, 161-173 (1993-01-01)
Douglas W Sborov et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(23), 5946-5955 (2014-10-09)
Reolysin, a proprietary isolate of reovirus type III dearing, enters and preferentially induces apoptosis of malignant cells. RAS pathway activation has been associated with more efficient reoviral infectivity and enhanced oncolysis. Reovirus is currently in advanced solid tumor phase I-II
Nathalia de Setta et al.
BMC genomics, 15, 540-540 (2014-07-06)
Sugarcane is the source of sugar in all tropical and subtropical countries and is becoming increasingly important for bio-based fuels. However, its large (10 Gb), polyploid, complex genome has hindered genome based breeding efforts. Here we release the largest and
Adrian J Waite et al.
Neurobiology of aging, 35(7), 1779-1779 (2014-02-25)
An intronic G(4)C(2) hexanucleotide repeat expansion in C9ORF72 is a major cause of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Several mechanisms including RNA toxicity, repeat-associated non-AUG translation mediated dipeptide protein aggregates, and haploinsufficiency of C9orf72 have been implicated in
Eve R Schneider et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(41), 14941-14946 (2014-09-24)
Relying almost exclusively on their acute sense of touch, tactile-foraging birds can feed in murky water, but the cellular mechanism is unknown. Mechanical stimuli activate specialized cutaneous end organs in the bill, innervated by trigeminal afferents. We report that trigeminal
Zoe B Spiers et al.
Diseases of aquatic organisms, 110(1-2), 151-164 (2014-07-26)
Winter mortality (WM) is a poorly studied disease affecting Sydney rock oysters Saccostrea glomerata in estuaries in New South Wales, Australia, where it can cause significant losses. WM is more severe in oysters cultured deeper in the water column and
Eleonora Fridman et al.
The Journal of biological chemistry, 287(9), 6518-6529 (2012-01-10)
Cardiac steroids (CS), an important class of naturally occurring compounds, are synthesized in plants and animals. The only established receptor for CS is the ubiquitous Na(+),K(+)-ATPase, a major plasma membrane transporter. The binding of CS to Na(+),K(+)-ATPase causes the inhibition
Stefano Comazzetto et al.
PLoS genetics, 10(10), e1004597-e1004597 (2014-10-21)
Male fertility requires the continuous production of high quality motile spermatozoa in abundance. Alterations in all three metrics cause oligoasthenoteratozoospermia, the leading cause of human sub/infertility. Post-mitotic spermatogenesis inclusive of several meiotic stages and spermiogenesis (terminal spermatozoa differentiation) are transcriptionally
Cheng-Han Wu et al.
PloS one, 10(2), e0116068-e0116068 (2015-02-12)
Although still debated, limb regeneration in salamanders is thought to depend on the dedifferentiation of remnant tissue occurring early after amputation and generating the progenitor cells that initiate regeneration. This dedifferentiation has been demonstrated previously by showing the fragmentation of
Koji Okudela et al.
PloS one, 9(6), e100581-e100581 (2014-07-01)
Small non-protein coding RNA, microRNA (miR), which regulate messenger RNA levels, have recently been identified, and may play important roles in the pathogenesis of various diseases. The present study focused on miR-31 and investigated its potential involvement in lung carcinogenesis.
A requirement for hedgehog signaling in thyroid hormone-induced postembryonic intestinal remodeling.
Luan Wen et al.
Cell & bioscience, 5, 13-13 (2015-04-11)
Intestinal remodeling during amphibian metamorphosis has long been studied as a model for the formation of the adult organs in vertebrates, especially the formation of adult organ-specific stem cells. Like all other processes during metamorphosis, this process is controlled by
Xiaohui Liu et al.
Journal of hematology & oncology, 8, 15-15 (2015-04-18)
DNA methyltransferase 1 (Dnmt1) regulates expression of many critical genes through maintaining parental DNA methylation patterns on daughter DNA strands during mitosis. It is essential for embryonic development and diverse biological processes, including maintenance of hematopoietic stem and progenitor cells
Wei Qin et al.
PloS one, 9(6), e100796-e100796 (2014-06-27)
Ribosome biogenesis is an important biological process for proper cellular function and development. Defects leading to improper ribosome biogenesis can cause diseases such as Diamond-Blackfan anemia and Shwachman-Bodian-Diamond syndrome. Nucleolar proteins are a large family of proteins and are involved
Glen P Carter et al.
International journal of medical microbiology : IJMM, 304(8), 1147-1159 (2014-09-06)
The clostridia cause many human and animal diseases, resulting in significant morbidity and mortality. Host damage results from the action of potent exotoxins, an important group of which is the large clostridial toxins (LCTs) produced by Clostridium difficile, Clostridium sordellii
Sylvie Baucheron et al.
The Journal of antimicrobial chemotherapy, 69(9), 2400-2406 (2014-05-13)
In Salmonella Typhimurium, the genes encoding the AcrAB-TolC multidrug efflux system are mainly regulated by the ramRA locus, composed of the divergently transcribed ramA and ramR genes. The acrAB and tolC genes are transcriptionally activated by RamA, the gene for
Victoria M Ho et al.
Molecular and cellular neurosciences, 61, 1-12 (2014-05-03)
AMPA-type glutamate receptors mediate fast, excitatory neurotransmission in the brain, and their concentrations at synapses are important determinants of synaptic strength. We investigated the post-transcriptional regulation of GluA2, the calcium-impermeable AMPA receptor subunit, by examining the subcellular distribution of its
Ryan Y Wong et al.
PloS one, 7(11), e50355-e50355 (2012-12-05)
Female mate choice behavior is a critical component of sexual selection, yet identifying the neural basis of this behavior is largely unresolved. Previous studies have implicated sensory processing and hypothalamic brain regions during female mate choice and there is a
Mélanie Makhlouf et al.
Nature communications, 5, 4878-4878 (2014-09-12)
Accumulation of the noncoding RNA Xist on one X chromosome in female cells is a hallmark of X-chromosome inactivation (XCI) in eutherians. Here we uncover an essential function for the ubiquitous autosomal transcription factor Yin-Yang 1 (YY1) in the transcriptional
Michael P Trombley et al.
PloS one, 10(4), e0124373-e0124373 (2015-04-23)
Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37. Resistance to LL-37, mediated by the sensitive to antimicrobial peptide (Sap) transporter, is required for H. ducreyi virulence in humans. Cationic APs
Joe Marcino
Journal of aquatic animal health, 25(2), 119-124 (2013-05-24)
Two methods for colorimetric in situ DNA probe hybridization (CISH) assays on paraffin-embedded tissue sections were compared. The heated method used heat (90-100°C) to denature DNA in the sample prior to probe hybridization, while the unheated method used a standard
Tina C Roeske et al.
PloS one, 9(11), e111722-e111722 (2014-11-14)
All-trans retinoic acid (ATRA), the main active metabolite of vitamin A, is a powerful signaling molecule that regulates large-scale morphogenetic processes during vertebrate embryonic development, but is also involved post-natally in regulating neural plasticity and cognition. In songbirds, it plays
C Kessler
Molecular and cellular probes, 5(3), 161-205 (1991-06-01)
A review is given on the novel non-radioactive digoxigenin:anti-digoxigenin (DIG) bioanalytical indicator system. After a general introduction on direct and indirect indicator systems based on previous non-radioactive indicator reactions as well as in vitro and in vivo amplification procedures the
Li Zhang et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(2), 787-798 (2014-10-09)
Whelming evidence has demonstrated that WW domain containing E3 ubiquitin protein ligase 1 (WWP1) participates in a wide variety of biological processes and is tightly related to the initiation and progression of many tumors. Currently, although mounting evidence supports a
E Amram et al.
Antimicrobial agents and chemotherapy, 59(2), 796-802 (2014-11-19)
Mycoplasma bovis isolates with decreased susceptibilities to tetracyclines are increasingly reported worldwide. The acquired molecular mechanisms associated with this phenomenon were investigated in 70 clinical isolates of M. bovis. Sequence analysis of the two 16S rRNA-encoding genes (rrs3 and rrs4
Yu Lei et al.
Laboratory investigation; a journal of technical methods and pathology, 94(11), 1283-1295 (2014-09-30)
The liver has the extraordinary properties of regeneration and immune tolerance; however, the mechanisms governing these abilities are poorly understood. To address these questions, we examined the possible expression of immunoglobulins in the human and rat liver and the relationship
Ying-Jey Guh et al.
Endocrinology, 155(5), 1728-1737 (2014-01-16)
Endothelin-1 (EDN1) is an important regulator of H⁺ secretion in the mammalian kidney. EDN1 enhances renal tubule H⁺-ATPase activity, but the underlying mechanism remains unclear. To further elucidate the role of EDN1 in vertebrates' acid-base regulation, the present study used
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