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Showing 1-30 of 33 results for "E16600" within Papers
Shuyun Dong et al.
Acta pharmacologica Sinica, 38(6), 914-923 (2017-04-18)
Cytotoxic T lymphocyte (CTL) epitope peptide-based vaccines are widely used in cancer and infectious disease therapy. We previously generated an immune-tolerant elastin-like polypeptides (iTEPs)-based carrier to deliver a peptide CTL vaccine and enhance the efficiency of the vaccine. To further
Chao Liu et al.
Molecular and cellular endocrinology, 424, 118-127 (2016-01-31)
The underlying mechanism leading to rupture of the membranes at parturition is not fully understood. Lysyl oxidase (LOX) cross-links collagen fibrils thereby increasing the tensile strength of the membranes. Thus, understanding the regulation of LOX expression may be of crucial
S Chimento et al.
Journal of wound care, 26(Sup9), S4-S8 (2017-09-08)
Osteopontin (OPN) is abundantly expressed during tissue repair, acting as a powerful chemokine that recruits inflammatory cells such as neutrophils, macrophages, and Langerhans cells. The role of OPN in chronic wounds has not been explored. In this study, we assess
Shengdi Wu et al.
Digestive diseases and sciences, 62(6), 1537-1549 (2017-04-04)
To investigate the protective effects of helix B surface peptide (HBSP) on acute liver injury induced by carbon tetrachloride (CCl HBSP (8 nmol/kg) was intraperitoneally injected into C57 BL/6 mice 2 h after CCl HBSP significantly decreased serum alanine aminotransferase, aspartate aminotransferase
Paola Pontrelli et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 30(9), 1480-1487 (2015-06-10)
Coagulation and complement activation represent key events in ischaemia-reperfusion-induced renal injury leading to delayed graft function (DGF). It is still unclear whether the coagulation cascade may also influence the acquired immunity. The aim of the present study was to investigate
An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells.
Peng Wang et al.
Theranostics, 8(1), 223-236 (2018-01-02)
Denzil Britto Christopher Leslee et al.
Luminescence : the journal of biological and chemical luminescence, 32(7), 1354-1360 (2017-06-21)
A new carbazole-azine based fluorescent sensor was synthesized and characterized. The selectivity of the sensor for Cu
Yuh-Pyng Sher et al.
American journal of cancer research, 8(12), 2528-2537 (2019-01-22)
The E6 and E7 oncoproteins of human papillomavirus (HPV) are ideal targets for developing immunotherapeutic approaches to treat HPV-associated tumors. Our previous studies showed that a recombinant lipidated HPV16 E7 mutant (rlipo-E7m) with inactivation of the E7 oncogenic functions can
Siyuan Zhang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(10), 10767-10779 (2019-07-10)
A tumor can be regarded as a cell mass with a biologic hierarchy that is orchestrated by cancer stem cells. The specific features of cancer stem cells may result from a series of gene expression regulatory mechanisms. As important regulatory
Expression of eukaryotic initiation factor 4E and 4E binding protein 1 in colorectal carcinogenesis.
Mona Diab-Assaf et al.
International journal of clinical and experimental pathology, 8(1), 404-413 (2015-03-11)
Cap dependent translation is mainly regulated at the level of the eukaryotic initiation factor 4E (eIF4E), the activity of which is controlled by phosphorylation and sequestration by its well established regulator, 4E binding protein 1 (4E-BP1). Both eIF4E and 4E-BP1
Kim van der Weerd et al.
Thyroid : official journal of the American Thyroid Association, 24(6), 1051-1061 (2014-03-19)
Using gene expression profiling, we detected differential thyrotropin receptor (TSH-R) expression during human T-cell development in the thymus. This expression pattern indicated a potential role for the TSH-R within the thymus, independent of its function in the thyroid gland. Here
Ken-ichiro Inoue et al.
Respiratory research, 6, 106-106 (2005-09-17)
Particulate matter (PM) can exacerbate allergic airway diseases. Although health effects of PM with a diameter of less than 100 nm have been focused, few studies have elucidated the correlation between the sizes of particles and aggravation of allergic diseases.
Yao-Lung Kuo et al.
Scientific reports, 9(1), 10269-10269 (2019-07-18)
Fibrosis has been considered as a major cause of capsular contracture. Hypoxia has widely emerged as one of the driving factors for fibrotic diseases. The aim of this study was to examine the association between hypoxia-induced fibrosis and breast capsular
Sara Vidal et al.
BMC veterinary research, 13(1), 373-373 (2017-12-05)
Coxiella burnetii, Chlamydia abortus and Leptospira spp. are difficult to grow bacteria that play a role in bovine abortion, but their diagnosis is hampered by their obligate intracellular lifestyle (C. burnetii, C. abortus) or their lability (Leptospira spp.). Their importance
Vaihere Delaune et al.
Cell transplantation, 25(12), 2259-2268 (2016-06-16)
Islet transplantation is an effective treatment for selected patients with type 1 diabetes. However, an accurate test still lacks for the early detection of graft rejection. Blood samples were prospectively collected in four university centers (Geneva, Grenoble, Montpellier, and Strasbourg).
Guanglin Cui et al.
Oncotarget, 8(28), 45311-45322 (2017-05-10)
Considerable evidence supports the idea that stem-like cells may play an essential role during the development of colorectal cancer (CRC). To accomplish this aim, we use immunohistochemistry (IHC) and double IHC with different potential stem-like markers, anti-musashi (Msi), anti-CD133, anti-
Sonja Schrack et al.
Photochemistry and photobiology, 94(5), 965-974 (2018-04-18)
For consumer safety reasons, cosmetics that are exposed to light are evaluated with respect to phototoxicity and/or photoallergy (photosensitization). For perfumes/aftershaves, however, these tests are not performed with the cosmetic product but only with single fragrance compounds, which may influence
Dan Tang et al.
Journal of cellular biochemistry, 120(9), 16128-16142 (2019-05-18)
Long noncoding RNA (lncRNA) is emerging as a vital regulator in various cancers. Recently, it was found that lncRNA colorectal neoplasia differentially expressed (CRNDE) plays an oncogenic role, promoting cell proliferation and migration in hepatocellular carcinoma (HCC). However, the underlying
Andrew Smith et al.
Biochimica et biophysica acta, 1865(7), 865-874 (2016-11-29)
Membranous Nephropathy (MN) is an immunocomplex mediated renal disease that represents one of the most frequent glomerulopathies worldwide. This glomerular disease can manifest as primary (idiopathic) or secondary and this distinction is crucial when choosing the most appropriate course of
Matthias Bozza et al.
Molecular therapy. Methods & clinical development, 17, 957-968 (2020-05-19)
We describe herein non-integrating minimally sized nano-S/MAR DNA vectors, which can be used to genetically modify dividing cells in place of integrating vectors. They represent a unique genetic tool, which avoids vector-mediated damage. Previous work has shown that DNA vectors
Stephanie S Tseng-Rogenski et al.
Gastroenterology, 148(3), 579-589 (2014-12-03)
Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) is the most common DNA mismatch repair defect in colorectal cancers, observed in approximately 60% of specimens. This acquired genotype correlates with metastasis and poor outcomes for patients, and is associated with
Merve Kara et al.
Macromolecular rapid communications, 36(23), 2070-2075 (2015-09-12)
A new phenacyl-type photoinitiator based on ethyl carbazole as a long wavelength photo-initiator is developed for free radical polymerization. Phenacyl ethyl carbazolium hexafluoroantimonate (PECH) photoinitiator is synthesized in a two-step, one-pot manner by quaternizing ethyl carbazole with phenacyl bromide and
Meagan J Gillespie et al.
BMC genomics, 14, 169-169 (2013-03-19)
The pigeon crop is specially adapted to produce milk that is fed to newly hatched young. The process of pigeon milk production begins when the germinal cell layer of the crop rapidly proliferates in response to prolactin, which results in
Jonas Blume et al.
European journal of immunology, 49(1), 121-132 (2018-10-04)
The interdependence of posttranscriptional gene regulation via miRNA and transcriptional regulatory networks in lymphocyte development is poorly understood. Here, we identified miR-191 as direct upstream modulator of a transcriptional module comprising the transcription factors Foxp1, E2A, and Egr1. Deletion as
Yu-rui Liu et al.
BMC gastroenterology, 14, 145-145 (2014-08-17)
Hepatitis B virus (HBV) infection is a serious public health problem worldwide. This study aimed to investigate the relationship between serum alpha-fetoprotein (AFP) levels and pathological stages of liver biopsy in patients with chronic hepatitis B (CHB). The study included
Thomas Westermann et al.
Veterinary pathology, 58(1), 114-122 (2020-11-19)
Despite previous detection of Chlamydia pecorum in sporadic ovine abortions, published descriptions of naturally occurring infections with fetoplacental lesions are lacking. This report provides the first descriptions of severe necrosuppurative chorionitis with vasculitis, and fetal pyelonephritis and enteritis in late-term
Seung Namgung et al.
The American journal of Chinese medicine, 45(3), 475-495 (2017-04-01)
Diabetic nephropathy is both the most common complication and the leading cause of mortality associated with diabetes. Prunella vulgaris, a well-known traditional medicinal plant, is used for the cure of abscess, scrofula, hypertension and urinary diseases. This study confirmed whether
Keith R Spencer et al.
Brain pathology (Zurich, Switzerland), 30(6), 1028-1040 (2020-07-08)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting both the upper and lower motor neurons. Although ALS typically leads to death within 3 to 5 years after initial symptom onset, approximately 10% of patients with ALS live more than
Chao Shan et al.
Nature communications, 10(1), 5677-5677 (2019-12-14)
An important goal of the Zika virus (ZIKV) vaccine is to prevent a congenital syndrome in fetuses of pregnant women, but studies directly evaluating maternal vaccination for ZIKV are lacking. Here we report maternal vaccination using a live-attenuated ZIKV vaccine (3'UTR-∆10-LAV) in
Denzil Britto Christopher Leslee et al.
Journal of fluorescence, 29(1), 75-89 (2018-11-11)
Carbazole - Rhodanine conjugate is an effective fluorescent host for silver ions through fluorometric transformation from green to red color with a hyperchromic emission. An intramolecular charge transfer process derived from carbazole towards rhodanine favors interaction of thiocarbonyl S and
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