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Showing 1-30 of 203 results for "E4884" within Papers
David E Moody et al.
Journal of analytical toxicology, 39(5), 374-386 (2015-04-15)
Opioid-related mortality rates have escalated. Drug interactions may increase blood concentrations of the opioid. We therefore used human liver microsomes (HLMs) and cDNA-expressed human cytochrome P450s (rCYPs) to study in vitro inhibition of buprenorphine metabolism to norbuprenorphine (CYP3A4 and 2C8)
He Zheng et al.
Bio-protocol, 5(23) (2015-12-05)
Filamentous fungi and bacteria form mixed-species biofilms in nature and diverse clinical contexts (Frey-Klett et al., 2011; Peleg et al., 2010). The interactions between fungi and bacteria, often mediated by secreted metabolites, have important ramifications for the biology of the
Clarissa Campbell et al.
Immunity, 48(6), 1245-1257 (2018-06-03)
The mammalian gut microbiota provides essential metabolites to the host and promotes the differentiation and accumulation of extrathymically generated regulatory T (pTreg) cells. To explore the impact of these cells on intestinal microbial communities, we assessed the composition of the
Lysozyme/EDTA disodium salt and modified-atmosphere packaging to prolong the shelf life of burrata cheese
Conte A, et al.
Journal of Dairy Science, 94(11), 5289-5297 (2011)
Xiang Gao et al.
Acta radiologica (Stockholm, Sweden : 1987), 55(3), 328-334 (2013-08-22)
Previous studies have demonstrated that magnetic resonance imaging may be a method of choice to visualize transplanted pancreatic islets. However, contrast agents may interfere with microcirculation and affect graft function. To evaluate the effects manganese-containing contrast media on regional blood
Jon Sin et al.
Journal of virology, 91(24) (2017-10-06)
Coxsackievirus B (CVB) is a common enterovirus that can cause various systemic inflammatory diseases. Because CVB lacks an envelope, it has been thought to be inherently cytolytic, wherein CVB can escape from the infected host cell only by causing it
Lynnae D Hyatt et al.
PloS one, 9(10), e109072-e109072 (2014-10-10)
Zinc finger protein 36, C3H type-like 1 (ZFP36L1) is one of several Zinc Finger Protein 36 (Zfp36) family members, which bind AU rich elements within 3' untranslated regions (UTRs) to negatively regulate the post-transcriptional expression of targeted mRNAs. The prototypical
Sandra Lara et al.
ACS nano, 11(2), 1884-1893 (2017-01-24)
Biomolecules adsorbed on nanoparticles are known to confer a biological identity to nanoparticles, mediating the interactions with cells and biological barriers. However, how these molecules are presented on the particle surface in biological milieu remains unclear. The central aim of
Olesya P Luzhetskaya et al.
Molecules (Basel, Switzerland), 25(19) (2020-10-09)
Linker H1 histone is one of the five main histone proteins (H1, H2A, H2B, H3, and H4), which are components of chromatin in eukaryotic cells. Here we have analyzed the patterns of DNA recognition by free H1 histone using a
G Lima-Oliveira et al.
British journal of biomedical science, 70(1), 6-9 (2013-04-27)
This study assesses the use of different dry K2 (dipotassium) EDTA vacuum tubes and whether or not they might represent a bias in haematological testing. Blood was collected in three dipotassium EDTA vacuum tubes from different manufacturers: Venosafe, Vacuette and
Nicolas Pineault et al.
Methods in molecular biology (Clifton, N.J.), 946, 205-224 (2012-11-28)
Megakaryocytes (MK) are hematopoietic cells present in the bone marrow that are responsible for the production and release of platelets in the circulation. Given their very low frequency (<1%), human MK often need to be derived in culture to study
Muthian Shanmugasundaram et al.
Current protocols, 1(1), e22-e22 (2021-01-24)
This article describes a reliable and efficient method for synthesis of the dinucleotide cap analog m7(LNA) G[5']ppp[5']G containing a locked nucleic acid moiety. The required LNA intermediate for the final coupling reaction, m7(LNA) GDP, is prepared in six steps starting
Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia.
Liu, et al.
Breast Cancer Research and Treatment, 198, 583-596 (2023)
Zhoumeng Lin et al.
Toxicological sciences : an official journal of the Society of Toxicology, 141(1), 90-102 (2014-06-11)
Atrazine (ATR) is one of the most frequently detected pesticides in the U.S. water supply. This study aimed to investigate neurobehavioral and neurochemical effects of ATR in C57BL/6 mouse offspring and dams exposed to a relatively low (3 mg/l, estimated
Anja Täuber et al.
International journal of pharmaceutics, 489(1-2), 73-82 (2015-04-22)
Fungal infections of skin and/or nails are common diseases resulting in major challenges in topical treatment. Therefore, the objective of the present study was to develop a dermal formulation targeting both tinea pedis and onychomycosis. The antifungal agent ciclopirox olamine
Serena Duchi et al.
Materials (Basel, Switzerland), 12(4) (2019-02-23)
Cartilage defects and diseases remain major clinical issues in orthopaedics. Biomanufacturing is now a tangible option for the delivery of bioscaffolds capable of regenerating the deficient cartilage tissue. However, several limitations of in vitro and experimental animal models pose serious
Gervasio A Lamas et al.
American heart journal, 168(1), 37-44 (2014-06-24)
Disodium ethylenediaminetetraacetic acid (EDTA) reduced adverse cardiac outcomes in a factorial trial also testing oral vitamins. This report describes the intent-to-treat comparison of the 4 factorial groups overall and in patients with diabetes. This was a double-blind, placebo-controlled, 2 ×
Anke M Smits et al.
Nature protocols, 4(2), 232-243 (2009-02-07)
To date, there is no suitable in vitro model to study human adult cardiac cell biology. Although embryonic stem cells are able to differentiate into cardiomyocytes in vitro, the efficiency of this process is very low. Other methods to differentiate
Soham Gupta et al.
Frontiers in immunology, 11, 437-437 (2020-04-01)
The hijacking of cellular function through expression of proteins that interfere with the activity of cellular enzymes and regulatory complexes is a common strategy used by viruses to remodel the cell environment in favor of their own replication and spread.
Octavian Bucur et al.
Frontiers in medicine, 5, 322-322 (2018-12-07)
Kidney glomerular diseases, such as the minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS), and other nephrotic syndromes, are typically diagnosed or confirmed via electron microscopy. Although optical microscopy has been a vital tool to examine clinical specimens for
Luminita David et al.
Colloids and surfaces. B, Biointerfaces, 122, 767-777 (2014-09-02)
This research aimed at reporting the synthesis, characterization and evaluation of the anti-inflammatory effects of some new biomaterials based on silver nanoparticles and polyphenols rich natural extracts. A fast and eco-friendly extracellular biosynthesis of silver nanoparticles (AgNPs), using European black
Salah Al Zadjali et al.
International journal of clinical and experimental medicine, 8(5), 7160-7167 (2015-07-30)
Lead is a widely-spread environmental pollutant and a commonly-used industrial chemical that can cause multisystemic adverse health effects. However, the effects of lead exposure on diabetic animals have not been reported so far. The aim of this study is to
Byeong-Won Kim et al.
Autophagy, 14(12), 2104-2116 (2018-08-08)
The initiation of macroautophagy/autophagy is tightly regulated by the upstream ULK1 kinase complex, which affects many downstream factors including the PtdIns3K complex. The phosphorylation of the right position at the right time on downstream molecules is governed by proper complex
Does calcium disodium EDTA slow CKD progression?
Weaver VM, et al.
American Journal of Kidney Diseases, 60(4), 503-506 (2012)
Marcela González-Vázquez et al.
Food science & nutrition, 10(4), 1146-1158 (2022-04-19)
Jicama root applications have focused on their nutraceutical properties without clearly specifying which compounds are related to this effect. Thus, the aim of the present study was to identify the changes in polysaccharides of nutraceutical interest in two commercial jicama
J X F Sim et al.
Journal of applied microbiology, 127(1), 99-108 (2019-05-06)
The antimicrobial activity of cinnamon essential oil and cinnamaldehyde against bacterial and fungal pathogens associated with canine otitis externa, as well as the effect of their combination with EDTA were investigated. Antimicrobial susceptibility testing was performed using the broth microdilution
Aditya Pandey et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 92(4), 269-278 (2014-06-20)
G-protein coupled receptors (GPCRs) are inherently dynamic membrane protein modulators of various important cellular signaling cascades. The apelin receptor (AR or APJ) is a class A GPCR involved in numerous physiological processes, implicated in angiogenesis during tumour formation and as
Philip Randall et al.
Food and nutrition bulletin, 33(4 Suppl), S344-S359 (2013-03-01)
Wheat and maize flour fortification is a preventive food-based approach to improve the micronutrient status of populations. In 2009, the World Health Organization (WHO) released recommendations for such fortification, with guidelines on the addition levels for iron, folic acid, vitamin
Mary K Sherwood et al.
Chemosphere, 113, 56-61 (2014-07-30)
Modified Fenton (MF) chemistry was tested in the laboratory to treat three diesel fuel-contaminated soils from the Canadian arctic rich in soil organic matter (SOM) and Fe oxides. Reactors were dosed with hydrogen peroxide (HP), and treatment was compared in
Santiago González-López et al.
The journal of adhesive dentistry, 15(5), 481-489 (2013-04-18)
To compare the percentage of collagen exposed in dentin root thirds after two irrigation protocols with manual or rotary instrumentation using two methacrylate resin-based sealers. Forty-eight single-root human teeth were prepared with manual (n = 24) or nickeltitanium ProFile rotary
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