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Showing 1-30 of 2416 results for "F3651" within Papers
Baosheng Zhou et al.
Medical oncology (Northwood, London, England), 32(1), 378-378 (2014-12-01)
Cell division cycle 2 (CDC2) is always overexpressed in malignant tumor cells and is correlated with chemosensitivity, but it is unclear whether CDC2 overexpression contributes to the chemoresistance potential of glioma cells. The aim of study was to determine the
Ang Tian et al.
International journal of nanomedicine, 10, 2423-2439 (2015-04-08)
Cells respond to their surroundings through an interactive adhesion process that has direct effects on cell proliferation and migration. This research was designed to investigate the effects of TiO2 nanotubes with different topographies and structures on the biological behavior of
B Heydenreich et al.
Clinical and experimental immunology, 176(3), 310-319 (2014-02-18)
Allergen-specific immunotherapy (SIT) is a clinically effective therapy for immunoglobulin (Ig)E-mediated allergic diseases. To reduce the risk of IgE-mediated side effects, chemically modified allergoids have been introduced. Furthermore, adsorbance of allergens to aluminium hydroxide (alum) is widely used to enhance
Patricia de Godoy Bueno et al.
PloS one, 10(4), e0124369-e0124369 (2015-04-30)
The purpose of this study was to investigate the effects of multiple infusions of allogeneic MSCs on glucose homeostasis and morphometry of pancreatic islets in high- fat diet (HFD) fed mice. Swiss mice were fed standard diet (C group) or
Young-Min Kim et al.
Biomaterials, 34(18), 4493-4500 (2013-03-19)
An approach for application of cell penetration to selective small interference RNA (siRNA) localized delivery system, cell penetrable nano-polyplex assembled hydrogel system, is presented. The cell penetrable nano-polyplex assembled hydrogelisprepared by protamine conjugation to poly(organophos-phazene) and inducement of nano-polyplexes with
S Dhawan et al.
Acta physiologica (Oxford, England), 213(4), 846-859 (2015-02-17)
Various types of cholinergic receptors are expressed on intestinal epithelia. Their function is not completely understood. We hypothesize that cholinergic receptor activation on epithelium may serve a protective function in cytokine-induced barrier dysfunction. The effect of cholinergic receptor activation on
Mohammad Anvari et al.
International journal of biological macromolecules, 79, 894-902 (2015-06-10)
The rheological and structural characteristics of fish gelatin (FG)-gum arabic (GA) complex coacervate phase, separated from an aqueous mixture of 1% FG and 1% GA at pH 3.5, were investigated as influenced by phase separation temperature. Decreasing the phase separation
Xinyu Zhuang et al.
BMC veterinary research, 11, 157-157 (2015-07-24)
Outbreaks of Marek's disease (MD), caused by Marek's disease virus (MDV), primarily occur in 10-12-week-old hens. We report a case of MD in a breeding flock of 24-30-week-old vaccinated broilers in China. The clinical signs in the affected chickens appeared
Sarah Ghamrawi et al.
PloS one, 9(6), e100290-e100290 (2014-06-21)
Progress in extending the life expectancy of cystic fibrosis (CF) patients remains jeopardized by the increasing incidence of fungal respiratory infections. Pseudallescheria boydii (P. boydii), an emerging pathogen of humans, is a filamentous fungus frequently isolated from the respiratory secretions
Anni E Sorkio et al.
Biomaterials, 51, 257-269 (2015-03-17)
The environmental cues received by the cells from synthetic substrates in vitro are very different from those they receive in vivo. In this study, we applied the Langmuir-Schaefer (LS) deposition, a variant of Langmuir-Blodgett technique, to fabricate a biomimetic microenvironment
Yu Jiao et al.
BioMed research international, 2014, 356415-356415 (2014-09-23)
To study possible nerve regeneration of a damaged auditory nerve by the use of stem cell transplantation. We transplanted HNPCs to the rat AN trunk by the internal auditory meatus (IAM). Furthermore, we studied if addition of BDNF affects survival
Science to Practice: dual contrast-enhanced MR imaging to monitor for rejection of pancreatic islet transplantation?
Olivier Clément
Radiology, 266(3), 693-694 (2013-02-23)
Charlotte Israelsson et al.
PloS one, 9(8), e104754-e104754 (2014-08-26)
Brain trauma is known to activate inflammatory cells via various chemokine signals although their interactions remain to be characterized. Mice deficient in Ccl3, Ccr2 or Cxcl10 were compared with wildtype mice after controlled cortical impact injury. Expression of Ccl3 in
Sudhir P Deosarkar et al.
PloS one, 10(11), e0142725-e0142725 (2015-11-12)
Studies of neonatal neural pathologies and development of appropriate therapeutics are hampered by a lack of relevant in vitro models of neonatal blood-brain barrier (BBB). To establish such a model, we have developed a novel blood-brain barrier on a chip
Xuhui Tong et al.
Oncology reports, 33(1), 207-214 (2014-10-31)
Platinum agents are widely used in the chemotherapy of testicular cancer. However, adverse reactions and resistance to such agents have limited their application in antineoplastic treatment. The aim of the present study was to determine the role of gap junction
Antonio Michelucci et al.
Internal and emergency medicine, 10(3), 329-335 (2014-11-13)
The aim of the study was to evaluate the association between circulating (CPCs) and endothelial (EPCs) progenitor cells and left ventricular (LV) remodeling in chronic heart failure (HF). 85 HF patients, ranging 29-89 years, 83.5% males, 45.9% ischemic, NYHA functional
Daoyi Miao et al.
Molecular medicine reports, 12(2), 1761-1768 (2015-04-22)
Obesity has been demonstrated to be involved in the progress of intervertebral disc degeneration (IDD). However, the associated mechanisms remain to be elucidated. The purpose the present study was to examine the effect of leptin on the expression of degeneration-associated
Eun-Mee Park et al.
PloS one, 10(7), e0132839-e0132839 (2015-07-18)
Hepatitis C virus (HCV) usurps host cellular lipid metabolism for production of infectious virus particles. Recently, we have screened a siRNA library targeting host factors that control lipid metabolism and lipid droplet (LD) formation in cell culture grown HCV (HCVcc)-infected
Anna Pérez-Bosque et al.
American journal of physiology. Gastrointestinal and liver physiology, 308(12), G1012-G1018 (2015-04-18)
Dietary supplementation with immunoglobulins from animal plasma has anti-inflammatory effects on intestinal and lung models of acute inflammation. Here, we aimed to establish whether dietary intervention with serum-derived bovine immunoglobulin (SBI) can prevent alterations in intestinal barrier function in a
Miguel A Pineda et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(6), 1492-1503 (2014-02-06)
The parasitic worm-derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17-associated cytokine IL-22 also appears to have a pathogenic role in autoimmune arthritis, particularly
P R B Silva et al.
Journal of dairy science, 98(7), 4449-4464 (2015-04-29)
The aim of this experiment was to determine effects of treating peripartum dairy cows with body condition score ≥3.75 with recombinant bovine somatotropin (rbST) on immune, inflammatory, and metabolic responses. Holstein cows (253±1d of gestation) were assigned randomly to 1
Xiaoyan Wang et al.
International journal of molecular sciences, 16(11), 26333-26346 (2015-11-12)
Spermatogonial stem cells (SSCs) renew themselves throughout the life of an organism and also differentiate into sperm in the adult. They are multipopent and therefore, can be induced to differentiate into many cells types in vitro. SSCs from pigs, considered
Keiichi Yamanaka et al.
The Journal of dermatology, 41(8), 679-685 (2014-08-08)
Therapy with monoclonal antibodies to tumor necrosis factor (TNF)-α and the interleukin (IL)-12/23 p40 subunit has significantly improved the clinical outcome of patients with psoriasis. These antibodies inhibit the effects of the target cytokines and thus the major concern during
Tomoki Katayose et al.
Biochemical and biophysical research communications, 460(4), 1069-1075 (2015-04-08)
Cas-L/NEDD9 is a cytoplasmic docking protein downstream of β1 integrin-mediated signaling pathway and is essential for cellular migration and β1 integrin-mediated costimulation of T cells. We previously found that increased number of Cas-L positive leukocytes migrated into the inflamed joints
Violet Aileen Senapati et al.
Journal of applied toxicology : JAT, 35(10), 1179-1188 (2015-06-19)
Chromium oxide (Cr2 O3 ) nanoparticles (NPs) are being increasingly used as a catalyst for aromatic compound manufacture, abrading agents and as pigments (e.g., Viridian). Owing to increased applications, it is important to study the biological effects of Cr2 O3 NPs
Nafiseh Masoumi et al.
Advanced healthcare materials, 3(6), 929-939 (2014-01-24)
Tissue engineered heart valves (TEHV) can be useful in the repair of congenital or acquired valvular diseases due to their potential for growth and remodeling. The development of biomimetic scaffolds is a major challenge in heart valve tissue engineering. One
Paola D'Andrea et al.
Biomaterials, 67, 240-253 (2015-08-02)
Mammalian adult skeletal muscle has a limited ability to regenerate after injury, usage or trauma. A promising strategy for successful regenerative technology is the engineering of bio interfaces that mimic the characteristics of the extracellular matrix. Human elastin-like polypeptides (HELPs)
Yigang Su et al.
Molecular pharmaceutics, 12(4), 1193-1202 (2015-03-10)
Here, a biodegradable polymer-drug conjugate of doxorubicin (DOX) conjugated with a stearic acid-grafted chitosan oligosaccharide (CSO-SA) was synthesized via disulfide linkers. The obtained polymer-drug conjugate DOX-SS-CSO-SA could self-assemble into nanosized micelles in aqueous medium with a low critical micelle concentration.
Sheng Xue et al.
International journal of clinical and experimental pathology, 8(4), 3765-3774 (2015-06-23)
accumulating evidence suggest that long non-coding RNAs (lncRNAs) may play important roles in human cancers. LncRNA neuroblastoma associated transcript-1 (NBAT-1) was initially identified to be involved in the progression of neuroblastoma. However, there is no report about the role of
Ana Lívia Silva Galbiatti et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 68(5), 515-519 (2014-04-23)
5-fluorouracil (5-FU) is an antifolate chemotherapeutic that has become established in many therapeutic regimes, but sensitivity variations and development of resistance are common problems that limit the efficiency of the treatments. Inter-individual variations to 5-FU outcome have been attributed to
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