Search Within
F3879
Applied Filters:
Keyword:'F3879'
Showing 1-30 of 237 results for "F3879" within Papers
Yutian Zhang et al.
Journal of molecular cell biology, 14(3) (2022-03-22)
The nuclear envelope comprises the outer nuclear membrane, inner nuclear membrane (INM), and nucleopore. Although ∼60 INM proteins have been identified, only a few of them have been well characterized, revealing their crucial roles. Our group focused on the INM
Jacob G Hodge et al.
Frontiers in medical technology, 5, 1194314-1194314 (2023-06-28)
Wound healing consists of a dynamic series of events that are highly dependent on paracrine factors for proper progression through the phases of wound healing. Inappropriate progression through the phases is associated with insufficient epidermal regeneration (i.e., re-epithelialization) of wounds
Kisung Lee et al.
Journal of biomedical optics, 22(9), 91516-91516 (2017-06-22)
Red blood cell (RBC) aggregation is an intrinsic property of the blood that has a direct effect on the blood viscosity and circulation. Nevertheless, the mechanism behind the RBC aggregation has not been confirmed and is still under investigation with
Daniel Dashevsky et al.
Toxicology letters, 337, 91-97 (2020-11-17)
Snakebite is a neglected tropical disease with a massive global burden of injury and death. The best current treatments, antivenoms, are plagued by a number of logistical issues that limit supply and access in remote or poor regions. We explore
Shravanthi Rajasekar et al.
Lab on a chip, 22(10), 1929-1942 (2022-04-07)
Organ-on-a-chip systems that recapitulate tissue-level functions have been proposed to improve in vitro-in vivo correlation in drug development. Significant progress has been made to control the cellular microenvironment with mechanical stimulation and fluid flow. However, it has been challenging to
Kazuma Takahashi et al.
Acta veterinaria Scandinavica, 55, 70-70 (2013-09-24)
Horse fibrinogen has been identified as a plasma specific ferritin-binding protein. There are two ways in the binding of ferritin-binding protein with ferritin: one is direct binding and the other is indirect binding which is heme-mediated. The aim of this
D Adelmann et al.
British journal of anaesthesia, 113(4), 628-633 (2014-05-30)
Postoperative haemorrhage in neurosurgery is associated with significant morbidity and mortality. There is controversy whether or not factor XIII (FXIII) deficiency leads to bleeding complications after craniotomy. Decreased fibrinogen levels have been associated with an increased incidence of bleeding complications
Etheresia Pretorius et al.
Cardiovascular diabetology, 16(1), 141-141 (2017-11-04)
We have previously shown that many chronic, inflammatory diseases are accompanied, and possibly partly caused or exacerbated, by various coagulopathies, manifested as anomalous clots in the form of 'dense matted deposits'. More recently, we have shown that these clots can
Cristina Solomon et al.
Anesthesia and analgesia, 117(5), 1054-1062 (2013-10-11)
The viscoelastic functional fibrinogen (FF) and FIBTEM assays measure the contribution of fibrin to clot strength. Inhibition of platelet function is a necessary precondition for these tests to work. We investigated a novel test for measuring fibrin-based clotting, FIBTEM PLUS
Fajer Almesbah et al.
Journal of neurosurgery. Pediatrics, 12(6), 615-621 (2013-10-08)
The frequency with which routine preoperative blood test results predict perioperative or postoperative complications is insignificant. The unnecessary ordering of routine tests increases the financial costs and patients' distress. The authors evaluated the effects of routine preoperative testing on patient
Paweł Trzaskoma et al.
Nature communications, 11(1), 2120-2120 (2020-05-03)
The human genome is extensively folded into 3-dimensional organization. However, the detailed 3D chromatin folding structures have not been fully visualized due to the lack of robust and ultra-resolution imaging capability. Here, we report the development of an electron microscopy
Gui-lian Xu et al.
Hepatology (Baltimore, Md.), 60(1), 114-124 (2014-03-08)
Viral fulminant hepatitis (FH) remains a serious clinical problem with very high mortality. Lacking understanding of FH pathogenesis has in essence hindered efficient clinical treatment. Inferring from a correlation observed between the genetic differences in the complement component 5 (C5)
Mette Thomsen et al.
JAMA, 309(22), 2353-2361 (2013-06-13)
Exacerbations of respiratory symptoms in chronic obstructive pulmonary disease (COPD) have profound and long-lasting adverse effects on patients. To test the hypothesis that elevated levels of inflammatory biomarkers in individuals with stable COPD are associated with an increased risk of
Manojkumar Varada et al.
ACS omega, 5(1), 498-506 (2020-01-21)
The synthesis of 4'-methoxymethyl threofuranosyl (4'-MOM-TNA) thymidine and derived oligomers of the G-rich thrombin-binding aptameric (TBA) sequence is reported. The G-quadruplex stability, anticoagulation activity, and the enzymatic stability of these oligomers bearing the 2'-3'-phosphodiester backbone as single substitutions in the
Anastasia Koroleva et al.
Biofabrication, 4(1), 015001-015001 (2012-01-20)
Fabrication of three-dimensional (3D) fibrin scaffolds with tightly controllable pore sizes and interconnections has been investigated. The scaffolds were produced using a combination of two-photon polymerization (2PP) and micromolding techniques. Master structures were fabricated by 2PP and regenerated in fibrin
Christian Zentai et al.
The Journal of surgical research, 187(2), 616-624 (2013-12-18)
Rapid control of hemorrhage is one of the key aspects in trauma handling. To cope with bleeding, local hemostatic approaches are useful, along with surgical and systemic homostatic therapy. In this experimental study, we investigated the efficacy of a fibrinogen/thrombin
Amanda B Payne et al.
Ethnicity & disease, 24(2), 169-174 (2014-05-09)
Venous thromboembolism (VTE) affects more than 300,000 people in the United States each year. However, it has been estimated that current diagnostic testing fails to identify prothrombotic risk in 50% of VTE patients. This article examines the relationship between levels
Zonghua Liu et al.
Biomaterials, 31(12), 3364-3373 (2010-02-04)
Hydrophobically derivatized hyperbranched polyglycerol (HPG)-polyethylene glycol (PEG) polymers bearing stearoyl chains (HPG-C18-PEG) were originally developed as human serum albumin substitutes and further as a unimolecular drug delivery system. In view of these in vivo applications and the potential for membrane
Tímea Feller et al.
Journal of structural biology, 203(3), 273-280 (2018-06-03)
Fibrin plays a fundamentally important role during hemostasis. To withstand the shear forces of blood flow and prevent embolisation, fibrin monomers form a three-dimensional polymer network that serves as an elastic scaffold for the blood clot. The complex spatial hierarchy
V S Rogovskiĭ et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(3), 23-26 (2013-06-19)
The ability of dihydroquercetin to inhibit the oxidation of fibrinogen has been evaluated. It is established that dihydroquercetin inhibits oxidation of fibrinogen by ozone, thus preventing oxidative modification of fibrinogen and preserving its functional activity.
Zhimin Song et al.
Biochemical pharmacology, 178, 114088-114088 (2020-06-13)
Phagocytes, especially neutrophils, can produce reactive oxygen species (ROS), through the activation of the NADPH oxidase (NOX2). Although this enzyme is crucial for host-pathogen defense, ROS production by neutrophils can be harmful in several pathologies such as cardiovascular diseases or
Justin C Luo et al.
Scientific reports, 10(1), 13144-13144 (2020-08-06)
We introduce laser cavitation rheology (LCR) as a minimally-invasive optical method to characterize mechanical properties within the interior of biological and synthetic aqueous soft materials at high strain-rates. We utilized time-resolved photography to measure cavitation bubble dynamics generated by the
Dao Lin et al.
iScience, 24(9), 102977-102977 (2021-09-07)
The effective utility of physiologically active molecules is crucial in numerous biological processes. However, the regulation of enzyme functions through active substances remains challenging at present. Here, glutathione (GSH), produced in cells, was used to modulate the catalytic activity of
Who advocates for cryoprecipitate?
Arturo Pereira et al.
Transfusion, 54(5), 1442-1443 (2014-05-14)
Anna Agren et al.
Anesthesia and analgesia, 118(5), 933-935 (2014-05-02)
Fibrinogen is of crucial importance in patients with ongoing bleeding. In this study, we compared fibrinogen concentration measured by thrombelastography (TEG®) with fibrinogen plasma concentration determined by Clauss. Sixty-three surgical patients and 38 healthy controls were included. For the whole
Shuxia Fan et al.
Bio-protocol, 8(18), e3018-e3018 (2018-09-20)
Blood platelets are critical for hemostasis and thrombosis, but also play diverse roles during immune responses. We have recently reported that platelets migrate at sites of infection in vitro and in vivo. Importantly, platelets use their ability to migrate to
Parveen K Garg et al.
Hypertension (Dallas, Tex. : 1979), 63(2), 413-419 (2013-11-06)
Prior studies evaluating metabolic syndrome (MetS) and incident peripheral artery disease (PAD) have been limited by use of modified MetS criteria and restriction to clinical PAD end points. We investigated MetS and risk of developing a low ankle-brachial index (ABI)
Brian L Mejak et al.
The journal of extra-corporeal technology, 45(2), 107-111 (2013-08-13)
The timing of blood product administration after cardiopulmonary bypass (CPB) may influence the amount of postoperative transfusion and chest tube output. We performed a retrospective study of a novel technique of administering blood products during modified ultrafiltration (MUF) in congenital
Ke Zhang et al.
Biomicrofluidics, 16(4), 044101-044101 (2022-07-19)
The vascular structure of the tumor microenvironment (TME) plays an essential role in the process of metastasis. In vitro microvascular structures that can be maintained for a long time will greatly promote metastasis research. In this study, we constructed a
Meriem Ameziani et al.
The protein journal, 39(5), 574-590 (2020-09-23)
The current report focuses on purification, structural and functional characterization of Cerastategrin from Cerastes cerastes venom, a novel basic disintegrin (pI 8.36) with 128 amino acid residues and a molecular weight of 13 835.25 Da measured by MALDI-MSMS. The 3D structure
Page 1 of 8