Clinical and Forensics Testing

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Syringe filter selection guide for HPLC, UHPLC, and Ion Chromatography using pore size, filter diameter, chemical compatibility, analyte binding, and extractables.

Syringe Filters

Answers to common syringe filter selection questions, such as sterile vs non-sterile, how to use, membrane and housing types, and pore size.

Determination of Protein by Bicinchoninic Acid Assay

BCA protein assay or Smith assay to determine protein concentration in a sample using Spectroquant® Prove photometers.

Newly Developed Porous Graphitic Carbon in U/HPLC

Polar graphitic carbon enables UHPLC separation of highly polar pesticides, herbicides, and Vitamin D metabolites, advancing liquid chromatography capabilities.

LC-MS Analysis of Warfarin™ in Plasma Samples

LC-MS analysis of Warfarin demonstrates its potential in clinical laboratories for accurate plasma measurements.

Fast Vitamin D Metabolite Analysis

Vitamin D deficiency affects bone health, highlighting its vital role in calcium absorption and bone growth.

Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid

This Sigma-Aldrich article continues to detail new methodology for the analysis of Vitamin D metabolites using HybridSPE-Phospholipid technology.

LC-MS Analysis of Serum for a Wide Analyte Range Using a Novel HLB SPE Phase

Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

SPME in the Analysis of Illicit Drugs

SPME is used in the analysis of amphetamine compounds by doing pre-extraction derivatization, and is also used in general determinations of other drugs of abuse.

Optimizing Serum Sample Preparation for Free Testosterone Determination: A Comparative Analysis Using BioSPME

Optimize serum samples for LC-MS/MS-based free testosterone determination using Supel™ BioSPME 96-pin device and validated equilibrium dialysis methods.

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