Cornelia von Baeckmann et al.
Journal of colloid and interface science, 589, 453-461 (2021-01-24)
The typical method for minimizing serum protein adsorption in biological settings and prolonging blood circulation time of nanoparticles, is to anchor hydrophilic polymers (e.g., poly(ethylene glycol), PEG) on the particle surface, which is most often done by covalent attachment (PEGylation).