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Showing 1-30 of 136 results for "G7141" within Papers
Linzhang Li et al.
Journal of cell science, 130(1), 190-202 (2016-09-23)
Loss of epithelial cell polarity promotes cell invasion and cancer dissemination. Therefore, identification of factors that disrupt polarized acinar formation is crucial. Reactive oxygen species (ROS) drive cancer progression and promote inflammation. Here, we show that the non-polarized breast cancer
Neelam Muizzuddin et al.
Journal of cosmetic science, 64(1), 1-8 (2013-03-02)
A major component to the etiology of acne is the growth and invasion by Propionibacterium acnes. Hydrogen peroxide is an excellent antimicrobial agent but is unstable in most formulations. We have developed a hydrogen peroxide generation system using the enzyme
Ahmad Anas Nagoor Gunny et al.
Pakistan journal of biological sciences : PJBS, 16(18), 960-964 (2014-02-08)
Production cost of enzyme is largely determined by the type of the strain and raw material used to propagate the strain. Hence, selection of the strain and raw materials is crucial in enzyme production. For Glucose oxidase (GOx), previous studies
Ting-Yin Yeh et al.
Talanta, 115, 718-723 (2013-09-24)
We have demonstrated sensitive detections of hydrogen peroxide (H2O2) and glucose using reduced graphene oxide decorated with carbon dots (C-dots@RGO). The C-dots@RGO prepared from catechin (reducing agent and carbon source) and graphene oxide via hydrothermal routes possesses excitation-wavelength-dependence photoluminescence (PL)
Youhui Lin et al.
Angewandte Chemie (International ed. in English), 51(50), 12579-12583 (2012-11-09)
A label-free, resettable, and colorimetric logic network has been realized by utilizing thermally regenerable cerium oxide nanoparticles and biocatalytic reactions. Coupling switchable CeO(2) nanoparticles with biocomputing would convert molecular recognition events into colorimetric outputs and make logic gates feasible to
Brittany A Martínez et al.
PLoS genetics, 16(11), e1009192-e1009192 (2020-11-24)
During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AMPs) that are produced in the fat body, an organ that
Amol Aher et al.
Current biology : CB, 30(11), 2175-2183 (2020-05-04)
Microtubules play a key role in cell division, motility, and intracellular trafficking. Microtubule lattices are generally regarded as stable structures that undergo turnover through dynamic instability of their ends [1]. However, recent evidence suggests that microtubules also exchange tubulin dimers
Tirupati Pawar et al.
Journal of food science and technology, 57(9), 3400-3408 (2020-07-31)
Study was aimed to produce atta for chapati, an Indian flat bread with low carbohydrate digestibility through different milling interventions; processing and formulating a functional ingredient mix (FM). Granulation, physico-chemical, rheological and chapati making characteristics of chakki atta, CA (control)
Sneha Mondal et al.
Analytica chimica acta, 1141, 180-193 (2020-11-30)
The tenfold lowering in binding energy for TU-Tyrosine in immobilized urease (Kb: 4.7 × 103) with respect to the native enzyme (Kb: 6.5 × 104) begets easy desorption of thiourea (TU) by glucose (GL) with an eventual formation of a more strong TU- GL
Glucose oxidase-An overview
Biotechnology Advances, 27(4), 489-501 (2009)
Kyongwan Kim et al.
Soft matter, 14(17), 3221-3231 (2018-04-20)
During the early developmental process of organisms, the formation of left-right laterality requires a subtle mechanism, as it is associated with other principal body axes. Any inherent chiral feature in an egg cell can in principal trigger this spontaneous breaking
Zach Geisterfer et al.
Bio-protocol, 7(7), e2217-e2217 (2017-04-05)
Kinesins play a role in organizing the mitotic spindle through the crosslinking of microtubules (MTs), made possible through binding sites at opposite ends of the holoenzyme. Here, we developed a method to test kinesin MT crosslinking action under physiological conditions.
Yi-Wen Chang et al.
Communications biology, 6(1), 427-427 (2023-04-19)
Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the generation of ATP in the extracellular environment to establish a suitable microenvironment and to be a potential target for
Nelson B Cole et al.
Experimental gerontology, 45(7-8), 596-602 (2010-01-26)
Mitochondria are a primary source as well a principal target of reactive oxygen species within cells. Using immunofluorescence microscopy, we have found that a number of mitochondrial matrix proteins are normally undetectable in formaldehyde-fixed cells permeabilized with the cholesterol-binding detergent
Jonathan Dudzik et al.
Biofabrication, 5(3), 035009-035009 (2013-07-25)
The efficient localization of increased levels of active enzymes onto conducting scaffolds is important for the development of enzyme-based biofuel cells. Cross-linked enzyme clusters (CEC) of glucose oxidase (GOx) constrained to functionalized carbon nanotubes (CEC-CNTs) were generated in order to
Neal I Callaghan et al.
Communications biology, 3(1), 229-229 (2020-05-13)
Primary adult cardiomyocyte (aCM) represent the mature form of myocytes found in the adult heart. However, culture of aCMs in particular is challenged by poor survival and loss of phenotype, rendering extended in vitro experiments unfeasible. Here, we establish murine
Daniel M Waldera-Lupa et al.
Biochimica et biophysica acta, 1834(12), 2843-2848 (2013-09-03)
Fragment analysis of proteins and peptides by mass spectrometry using collision-induced dissociation (CID) revealed that the pairwise generated N-terminal b- and C-terminal y-ions have different stabilities resulting in underrepresentation of b-ions. Detailed analyses of large-scale spectra databases and synthetic peptides
Jennifer L Ross et al.
Biophysical journal, 94(8), 3115-3125 (2008-01-30)
Kinesin and cytoplasmic dynein are microtubule-based motor proteins that actively transport material throughout the cell. Microtubules can intersect at a variety of angles both near the nucleus and at the cell periphery, and the behavior of molecular motors at these
Xiaonan Du et al.
PloS one, 6(5), e19583-e19583 (2011-05-17)
Inflammation is associated with perinatal brain injury but the underlying mechanisms are not completely characterized. Stimulation of Toll-like receptors (TLRs) through specific agonists induces inflammatory responses that trigger both innate and adaptive immune responses. The impact of engagement of TLR2
BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation.
Jaya G Yodh et al.
The EMBO journal, 28(4), 405-416 (2009-01-24)
Bloom syndrome (BS) is a rare genetic disorder characterized by genomic instability and a high predisposition to cancer. The gene defective in BS, BLM, encodes a member of the RecQ family of 3'-5' DNA helicases, and is proposed to function
Zhengpeng Yang et al.
Biosensors & bioelectronics, 51, 268-273 (2013-08-27)
Core-shell Fe3O4-enzyme-polypyrrole (Ppy) nanoparticles with excellent magnetism and conductivity were successfully prepared via the surface modification and enzyme self-encapsulation within Ppy. A novel potentiometric glucose biosensor has been constructed by effectively attaching the proposed Fe3O4-enzyme-Ppy nanoparticles to the surface of
Samudra Sengupta et al.
Journal of the American Chemical Society, 135(4), 1406-1414 (2013-01-12)
Using fluorescence correlation spectroscopy, we show that the diffusive movements of catalase enzyme molecules increase in the presence of the substrate, hydrogen peroxide, in a concentration-dependent manner. Employing a microfluidic device to generate a substrate concentration gradient, we show that
Karnit Bahartan et al.
Chemical communications (Cambridge, England), 48(98), 11957-11959 (2012-11-06)
Yeast displaying glucose oxidase on their surface were encapsulated in a graphene oxide hydrogel. The ability of the modified yeast to reduce graphene oxide by glucose assimilation while maintaining viability was tested with time and deemed suitable for biofuel cell
Jian-Hu Li et al.
Biomacromolecules, 14(9), 2984-2988 (2013-08-22)
A biomimetic energy converter was fabricated via the assembly of CF0F1-ATPase on lipid-coated hollow nanocapsules composed of α-cyclodextrins/chitosan-graft-poly(ethylene glycol) methacrylate. Upon entrapped GOD into these capsules, the addition of glucose could trigger proton-motive force and then drive the rotation of
Penny C Molyneux et al.
Current protocols in mouse biology, 5(4), 311-329 (2015-12-03)
Circadian rhythms regulate many aspects of behavior and physiological processes, and, through external signals, help an organism entrain to its environment. These rhythms are driven by circadian clocks in many cells and tissues within our bodies, and are synchronized by
Kamendra P Sharma et al.
Advanced materials (Deerfield Beach, Fla.), 28(8), 1597-1602 (2015-12-18)
Dynamic protein-polymer surfactant films are highly hydrophilic and show a soft solid to hydrogel transition upon hydration to produce a swollen hydrogel. An unusual reversible autospreading/self-folding response is observed when the water-saturated films are transferred from water into air.
Chunxiao Hu et al.
IEEE transactions on bio-medical engineering, 67(9), 2417-2426 (2020-02-06)
Early stage diagnosis of sepsis without overburdening health services is essential to improving patient outcomes. A fast and simple-to-use platform that combines an integrated circuit with paper microfluidics for simultaneous detection of multiple-metabolites appropriate for diagnostics was presented. Paper based
John H Grabber et al.
BMC plant biology, 10, 114-114 (2010-06-23)
Recent discoveries highlighting the metabolic malleability of plant lignification indicate that lignin can be engineered to dramatically alter its composition and properties. Current plant biotechnology efforts are primarily aimed at manipulating the biosynthesis of normal monolignols, but in the future
Yuanmo Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 36(1), 37-46 (2019-12-24)
Enzymes conjugated to nanomaterials are used in the design of various biotechnologies. In the development of biosensors, surface modifications with the enzyme glucose oxidase (GOx) serve to aid the detection of blood glucose. In order to optimize sensor effectiveness, the
Ana Rita Costa et al.
eLife, 9 (2020-03-21)
Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and loss-of-function assays, we show that in rat hippocampal neurons the MPS is an actomyosin network that controls axonal expansion
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