G7532

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Showing 1-14 of 14 results for "G7532" within Papers

Engineered Paramagnetic Graphene Quantum Dots with Enhanced Relaxivity for Tumor Imaging.

Yuqi Yang et al.

Nano letters, 19(1), 441-448 (2018-12-19)

Nano contrast agents (Nano CA) are nanomaterials used to increase contrast in the medical magnetic resonance imaging (MRI). However, the related relaxation mechanism of the Nano CA is not clear yet and little significant breakthrough in relaxivity enhancement has been

Characterization of vector-based delivery of neurogenin-3 in murine diabetes.

Neil Phillips et al.

Human gene therapy, 25(7), 651-661 (2014-03-19)

Treatment of type 1 diabetes with gene transfer-induced cellular reprogramming requires a pancreatic transcription factor such as Neurogenin-3 (Ngn3) and as of yet unknown component of the adenoviral particle. Despite intensive study, there are many unsolved processes related to the

Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection.

Moumita Basu et al.

Journal of cell science, 133(7) (2020-02-23)

Intracellular survival of Leishmania donovani demands rapid production of host ATP for its sustenance. However, a gradual decrease in intracellular ATP in spite of increased glycolysis suggests ATP efflux during infection. Accordingly, upon infection, we show here that ATP is

Cellular effects of nicotine salt-containing e-liquids.

Arunava Ghosh et al.

Journal of applied toxicology : JAT, 41(3), 493-505 (2020-10-10)

"Pod-based" e-cigarettes such as JUUL are currently the most prevalent electronic nicotine delivery systems (ENDS) in the United States. JUUL-type ENDS utilize nicotine salts protonated with benzoic acid rather than freebase nicotine. However, limited information is available on the cellular

Preoperative Detection and Intraoperative Visualization of Brain Tumors for More Precise Surgery: A New Dual-Modality MRI and NIR Nanoprobe.

Chunyan Li et al.

Small (Weinheim an der Bergstrasse, Germany), 11(35), 4517-4525 (2015-06-11)

In clinical practice, it is difficult to identify tumor margins during brain surgery due to its inherent infiltrative character. Herein, a unique dual-modality nanoprobe (Gd-DOTA-Ag2S QDs, referred as Gd-Ag2S nanoprobe) is reported, which integrates advantages of the deep tissue penetration

Lanthanum (III) nitrate hexahydrate or gadolinium (III) chloride hexahydrate catalyzed one-pot synthesis of alpha-amino nitriles

Narasimhulu M, et al.

J. Mol. Catal. A: Chem., 264(1-2), 288-292 (2007)

P2RX2 and P2RX4 receptors mediate cation absorption in transitional cells and supporting cells of the utricular macula.

Junhui Jeong et al.

Hearing research, 386, 107860-107860 (2019-12-24)

Purinergic receptors protect the cochlea during high-intensity stimulation by providing a parallel shunt pathway through non-sensory neighboring epithelial cells for cation absorption. So far, there is no direct functional evidence for the presence and type/subunit of purinergic receptors in the

Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.

Geou-Yarh Liou et al.

Cancer discovery, 5(1), 52-63 (2014-11-02)

Desmoplasia and an inflammatory environment are defining features of pancreatic cancer. Unclear is how pancreatic cells that undergo oncogenic transformation can cross-talk with immune cells and how this contributes to the development of pancreatic lesions. Here, we demonstrate that pancreatic

Genetic Reprogramming of Positional Memory in a Regenerating Appendage.

Ying-Ting Wang et al.

Current biology : CB, 29(24), 4193-4207 (2019-12-02)

Certain vertebrates such as salamanders and zebrafish are able to regenerate complex tissues (e.g., limbs and fins) with remarkable fidelity. However, how positional information of the missing structure is recalled by appendage stump cells has puzzled researchers for centuries. Here

Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents.

Simone Rodrigues Silva et al.

Bioinorganic chemistry and applications, 2015, 942147-942147 (2015-09-09)

Complexes of gadolinium(III) with N-octanoyl-N-methylglucamine (L8) and N-decanoyl-N-methylglucamine (L10) with 1 : 2 stoichiometry were synthesized and characterized by elemental analysis, electrospray ionization-tandem mass spectrometry (ESI-MS), infrared (IR) spectroscopy, and molar conductivity measurements. The transverse (r 2) and longitudinal (r 1) relaxivity

T 1-T 2 dual-modal MRI contrast agents based on superparamagnetic iron oxide nanoparticles with surface attached gadolinium complexes

Szpak A, et al.

Journal of Nanoparticle Research, 16(11), 2678-2678 (2014)

N-benzhydryl quinuclidine compounds are a potent and Src kinase-independent inhibitor of NALCN channels.

Suyun Hahn et al.

British journal of pharmacology, 177(16), 3795-3810 (2020-05-22)

NALCN is a Na+ leak, GPCR-activated channel that regulates the resting membrane potential and neuronal excitability. Despite numerous possible roles for NALCN in both normal physiology and disease processes, lack of specific blockers hampers further investigation. The effect of N-benzhydryl

A multifunctional polymeric nanotheranostic system delivers doxorubicin and imaging agents across the blood-brain barrier targeting brain metastases of breast cancer.

Jason Li et al.

ACS nano, 8(10), 9925-9940 (2014-10-14)

Metastatic brain cancers, in particular cancers with multiple lesions, are one of the most difficult malignancies to treat owing to their location and aggressiveness. Chemotherapy for brain metastases offers some hope. However, its efficacy is severely limited as most chemotherapeutic

The gadolinium-based contrast agent Omniscan® promotes in vitro fibroblast survival through in situ precipitation.

Min Feng et al.

Metallomics : integrated biometal science, 7(7), 1103-1110 (2015-04-14)

The current study aims to explore how the gadolinium (Gd)-based contrast agent (GBCA) Omniscan® enhanced cell viability of murine fibroblasts. The results of scanning electron microscopy showed that Omniscan® can precipitate in cell culture media and deposit on cell membranes.

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