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Showing 1-28 of 28 results for "GF02183217" within Papers
B Lambert et al.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 53(3), 305-310 (2009-06-13)
Rhenium-188 (188Re) is a high energy beta-emitter with a physical half life of 17 hours. Various 188Re based radiopharmaceuticals were developed to treat liver malignancies. The vast majority of studies focus on patients suffering from hepatocellular carcinoma (HCC). Most radiopharmaceuticals
F M van der Zant et al.
Clinical and experimental rheumatology, 27(1), 130-139 (2009-03-31)
To perform a systemic review and meta-analysis on the effectiveness of radiosynoviorthesis (RSO). A search of medical databases was conducted. Criteria for inclusion: articles in English, minimum follow-up of 6 months, specification of joint disease, reported outcome of at least
Daisuke Suzuki et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 96, 52-56 (2014-12-06)
Uranium and plutonium isotope ratios in individual uranium-plutonium (U-Pu) mixed particles with various U/Pu atomic ratios were analyzed without prior chemical separation by thermal ionization mass spectrometry (TIMS). Prior to measurement, micron-sized particles with U/Pu ratios of 1, 5, 10
Christiane A Kluba et al.
Molecules (Basel, Switzerland), 18(3), 3206-3226 (2013-03-14)
The Click-to-Chelate approach is a highly efficient strategy for the radiolabeling of molecules of medicinal interest with technetium and rhenium-tricarbonyl cores. Reaction of azide-functionalized molecules with alkyne prochelators by the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC; click reaction) enables the simultaneous synthesis
M R A Pillai et al.
Current radiopharmaceuticals, 5(3), 228-243 (2012-05-31)
Rhenium-188 is one of the most readily available generator derived and useful radionuclides for therapy emitting β(-) particles (2.12 MeV, 71.1% and 1.965 MeV, 25.6%) and imageable gammas (155 keV, 15.1%). The (188)W/(188)Re generator is an ideal source for the
Philippe Collery et al.
Anticancer research, 34(4), 1679-1689 (2014-04-03)
We proposed a new water-soluble rhenium diseleno-ether compound (with one atom of Re and two atoms of Se) and investigated the uptake of Re into the nucleus of malignant cells in culture exposed to the compound for 48 h and
N Iznaga-Escobar
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 54(3), 399-406 (2001-02-24)
188Re is one of the radioisotopes expected to emerge as useful for therapy. Development of new radiopharmaceuticals based on 188Re depends on the radiolabeling methods used, which would give stable complexes having predefined radiochemical properties and in vitro and in
Mark Bartholomä et al.
Chemical communications (Cambridge, England), (5)(5), 493-512 (2009-03-14)
Radiolabeled biomolecules can be used to visualize a variety of diseases through interaction with specific cell receptors. A key step is the introduction of a molecular entity that allows facile labeling with the medically useful radionuclide (99m)Tc without significant alteration
Peter Wolohan et al.
Steroids, 72(3), 247-260 (2007-02-07)
OPLS all atom force field parameters were developed in order to model a diverse set of novel rhenium based estrogen receptor ligands whose relative binding affinities (RBA) to the estrogen receptor alpha isoform (ERalpha) with respect to 17beta-estradiol were available.
A T Porter et al.
Current opinion in oncology, 6(6), 607-610 (1994-11-01)
New advances in systemic radionuclide therapy have increased the number of treatment options available for patients with painful osseous metastases. This form of therapy has three major appeals: 1) it addresses all sites of involvement; 2) selective absorption into bone
Malcolm Frier
Mini reviews in medicinal chemistry, 4(1), 61-68 (2004-02-03)
The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular
Radiolabeling of monoclonal antibodies and fragments with technetium and rhenium.
G L Griffiths et al.
Bioconjugate chemistry, 3(2), 91-99 (1992-03-01)
R Klett et al.
Rheumatology (Oxford, England), 46(10), 1531-1537 (2007-06-29)
Hypertrophy and inflammation of the synovium with various underlying pathologies - such as rheumatoid arthritis, osteoarthritis, haemophilia and spondyloarthropathy - can be treated successfully by radiosynoviorthesis (RSO). For medium-sized joints (shoulder, elbow, wrist, hip and ankle), the radionuclide of choice
Sarah Theiner et al.
Metallomics : integrated biometal science, 7(8), 1256-1264 (2015-04-10)
The selection of drug candidates for entering clinical development relies on in vivo testing in (solid) tumor animal models. However, the heterogeneity of tumor tissue (e.g. in terms of drug uptake or tissue composition) is rarely considered when testing novel
F F Knapp
Cancer biotherapy & radiopharmaceuticals, 13(5), 337-349 (2000-06-14)
Rhenium-188 (188Re) is an important therapeutic radioisotope which is obtained on demand as carrier-free sodium perrhenate by saline elution of the tungsten-188/rhenium-188 generator system. With a half-life of 16.9 hours and emission of a high energy beta particle (maximal energy
L Alejo et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 103, 43-47 (2015-06-07)
Maximum Hp(0.07) dose to the eye lens received in a year by the pediatric interventional cardiologists has been estimated. Optically stimulated luminescence dosimeters were placed on the eyes of an anthropomorphic phantom, whose position in the room simulates the most
Kaixiong Ye et al.
BMC genetics, 16, 61-61 (2015-06-10)
HFE, a major regulator of iron (Fe) homeostasis, has been suggested to be under positive selection in both European and Asian populations. While the genetic variant under selection in Europeans (a non-synonymous mutation, C282Y) has been relatively well-studied, the adaptive
Jeremiah E Miller et al.
Biochimica et biophysica acta, 1655(1-3), 59-63 (2004-04-22)
Laser flash-quench methods have been used to generate tyrosine and tryptophan radicals in structurally characterized rhenium-modified Pseudomonas aeruginosa azurins. Cu(I) to "Re(II)" electron tunneling in Re(H107) azurin occurs in the microsecond range. This reaction is much faster than that studied
Frank R Cichocki et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 94(2), 493-500 (2010-06-25)
Suture needles are essential instruments for performing blood vessel anastomosis in coronary artery bypass graft (CABG) surgeries. Exceptional needle performance is needed now as never before because of the increasing prevalence of elderly patients with advanced stages of coronary disease
Francesco Tisato et al.
Mass spectrometry reviews, 23(5), 309-332 (2004-07-21)
Diagnostic nuclear medicine (NM) is among the imaging procedures (together with X-ray, computerized tomography, magnetic resonance, and echography) the clinicians can routinely adopt to image organs or tissues and related disorders. (99m)Tc-based agents are the radiopharmaceuticals of election in diagnostic
Sergey S Lobanov et al.
Scientific reports, 5, 13582-13582 (2015-09-02)
Rocky planets are thought to comprise compounds of Mg and O as these are among the most abundant elements, but knowledge of their stable phases may be incomplete. MgO is known to be remarkably stable to very high pressure and
Fabio Zobi
Chimia, 64(4), 259-265 (2010-12-09)
Transition metal complexes of rhenium and technetium find wide application in nuclear medicine and the chemistry of these elements is still the focus of intense research efforts. For therapeutic and diagnostic applications, currently much attention is dedicated to the development
Pierina Visciano et al.
Journal of food protection, 78(9), 1719-1728 (2015-09-01)
Concentrations of pollutants with regulatory limits were determined in specimens of Chamelea gallina, a species of clam collected along the Abruzzi coastal region of the central Adriatic Sea. Nine sampling sites were selected to evaluate the distribution of contaminants in
Justyna Scheffler et al.
Nuclear medicine review. Central & Eastern Europe, 6(1), 55-57 (2003-11-06)
Radionuclide bone metastases therapy is a major achievement of nuclear medicine. Development of less radiotoxic and more effective radiopharmaceuticals is therefore a challenge for radiopharmacists and industry. This paper reviews the application of rhenium-188 HEDP as a reactor- or generator-produced
Sahar Hiram-Bab et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(5), 1890-1900 (2015-01-30)
Erythropoietin (EPO) primarily regulates red blood cell formation, and EPO serum levels are increased on hypoxic stress (e.g., anemia and altitude). In addition to anemia, recent discoveries suggest new therapeutic indications for EPO, unrelated to erythropoiesis. We investigated the skeletal
Yu Lim Kim et al.
Physical chemistry chemical physics : PCCP, 17(11), 7435-7442 (2015-02-24)
We present a facile synthetic route to ruthenium dioxide (RuO2)-rhenium oxide (ReO3) electrospun composite nanofibers and their electrocatalytic responses for capacitance and H2O2 sensing. The contents of rhenium oxide of electrospun ruthenium dioxide (RuO2) were carefully controlled by an electrospinning
Adam Karpiński et al.
Journal of AOAC International, 97(4), 1213-1219 (2014-08-26)
The Abraham-Carr retention time prediction model was reviewed and developed in the context of the introduction of a new stationary phase variable. The new variable consists of a binary mixture dielectric constant and a stationary phase descriptor that was derived
John Parnell et al.
Nature communications, 6, 6996-6996 (2015-05-20)
Trace metal data for Proterozoic marine euxinic sediments imply that the expansion of nitrogen-fixing cyanobacteria and diversification of eukaryotes were delayed while the availability of bioessential metals such as molybdenum in the ocean was limited. However, there is increasing recognition
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