H0137

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Showing 1-10 of 10 results for "H0137" within Papers

Inhibition of the NKp44-PCNA Immune Checkpoint Using a mAb to PCNA.

Kiran Kundu et al.

Cancer immunology research, 7(7), 1120-1134 (2019-06-06)

mAb-based blocking of the immune checkpoints involving the CTLA4-B7 and PD1-PDL1 inhibitory axes enhance T-cell-based adaptive immune responses in patients with cancer. We show here that antitumor responses by natural killer (NK) cells can be enhanced by a checkpoint-blocking mAb

Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies.

Ellen Young et al.

Cell host & microbe, 27(5), 710-724 (2020-05-15)

The rational design of dengue virus (DENV) vaccines requires a detailed understanding of the molecular basis for antibody-mediated immunity. The durably protective antibody response to DENV after primary infection is serotype specific. However, there is an incomplete understanding of the

In vitro cultivation of Babesia duncani (Apicomplexa: Babesiidae), a zoonotic hemoprotozoan, using infected blood from Syrian hamsters (Mesocricetus auratus).

Kimberly A McCormack et al.

Parasitology research, 118(8), 2409-2417 (2019-06-15)

Human babesiosis, a tick-borne disease similar to malaria, is most often caused by the hemoprotozoans Babesia divergens in Europe, and Babesia microti and Babesia duncani in North America. Babesia microti is the best documented and causes more cases of human

Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity.

Indre Kucinskaite-Kodze et al.

Biomolecules, 10(7) (2020-07-12)

The pathogenicity of many bacteria, including Streptococcus pneumoniae, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing cell membranes. Therefore, PFTs-neutralising antibodies may provide useful tools for reducing S. pneumoniae pathogenic effects. This

Simulated Cholinergic Reinnervation of beta (INS-1) Cells: Antidiabetic Utility of Heterotypic Pseudoislets Containing beta Cell and Cholinergic Cell

Jiao A, et al.

International Journal of Endocrinology, 2018 (2018)

Characterization of an IgG monoclonal antibody targeted to both tissue cyst and sporocyst walls of Toxoplasma gondii

Gondim L, et al.

Experimental Parasitology, 163, 46-56 (2016)

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection.

Taylor B Engdahl et al.

Cell reports, 35(5), 109086-109086 (2021-05-06)

New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here, we

TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A.

Jun Ho Ko et al.

Cell reports, 33(12), 108543-108543 (2020-12-29)

DNA damage tolerance (DDT) and homologous recombination (HR) stabilize replication forks (RFs). RAD18/UBC13/three prime repair exonuclease 2 (TREX2)-mediated proliferating cell nuclear antigen (PCNA) ubiquitination is central to DDT, an error-prone lesion bypass pathway. RAD51 is the recombinase for HR. The

The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress

Hashiguchi K, et al.

Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis, 808, 10-19 (2018)

Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein.

Michael P Doyle et al.

Cell reports, 36(9), 109628-109628 (2021-09-02)

Hendra virus and Nipah virus (NiV), members of the Henipavirus (HNV) genus, are zoonotic paramyxoviruses known to cause severe disease across six mammalian orders, including humans. We isolated a panel of human monoclonal antibodies (mAbs) from the B cells of

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