Christine E Engeland et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(11), 1949-1959 (2014-08-27)
We hypothesized that the combination of oncolytic virotherapy with immune checkpoint modulators would reduce tumor burden by direct cell lysis and stimulate antitumor immunity. In this study, we have generated attenuated Measles virus (MV) vectors encoding antibodies against CTLA-4 and