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Showing 1-30 of 108 results for "H7379" within Papers
Nai-Jia Huang et al.
Nature communications, 8(1), 423-423 (2017-09-06)
A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs. Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface
Megumi Kobayashi et al.
Neuroreport, 23(17), 984-988 (2012-10-24)
We studied whether 5-month-old to 8-month-old infants process faces in a size-invariant manner by applying the fNIRS-adaptation paradigm used in our previous study. We used near-infrared spectroscopy to measure hemodynamic responses in the temporal regions of infants' brains during the
Megan Lim et al.
Journal of assisted reproduction and genetics, 38(6), 1363-1372 (2021-05-31)
Oxygen is vital for oocyte maturation; however, oxygen regulation within ovarian follicles is not fully understood. Hemoglobin is abundant within the in vivo matured oocyte, indicating potential function as an oxygen regulator. However, hemoglobin is significantly reduced following in vitro
James V Lee et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 199(3), 227-238 (2013-01-17)
Songbirds communicate by learned vocalizations with concomitant changes in neurophysiological and genomic activities in discrete parts of the brain. Here, we tested a novel implementation of diffusive optical imaging (also known as diffuse optical imaging, DOI) for monitoring brain physiology
R Kannan et al.
International journal for numerical methods in biomedical engineering, 28(11), 1093-1106 (2012-10-31)
Near infrared spectroscopy (NIRS) is a technique used to detect and measure changes in the concentrations of oxygenated hemoglobin, deoxygenated hemoglobin, and water in tissues based on the differential absorption, scattering, and refraction of the near infrared light. In this
Camille Bergtold et al.
Biomacromolecules, 19(9), 3693-3704 (2018-08-01)
The oxidation of dopamine and of other catecholamines leads to the formation of conformal films on the surface of all known materials and to the formation of a precipitate in solution. In some cases, it has been shown that the
Molecular interaction of silicon quantum dot micelles with plasma proteins: hemoglobin and thrombin.
Shanmugavel Chinnathambi et al.
RSC advances, 9(26), 14928-14936 (2019-05-14)
Protein conformational changes are associated with potential cytotoxicity upon interaction with small molecules or nanomaterials. Protein misfolding leads to protein-mediated diseases; thus, it is important to study the conformational changes in proteins using nanoparticles as drug carriers. In this study
Guishan Zheng et al.
Biochemistry, 52(47), 8539-8555 (2013-11-15)
The Bohr effect in hemoglobin, which refers to the dependence of the oxygen affinity on the pH, plays an important role in its cooperativity and physiological function. The dominant contribution to the Bohr effect arises from the difference in the
Lingling Xu et al.
Cell reports, 41(8), 111709-111709 (2022-11-24)
The function of fibroblasts in intracerebral hemorrhage (ICH) remains elusive. By targeting Col1α1, a fibroblast-specific marker, we generate mice with ablated Col1α1+ fibroblasts. These mutants show exacerbated blood-brain barrier (BBB) damage, enlarged injury volume, and worse neurological function, highlighting a
Bing Yu et al.
Methods in molecular biology (Clifton, N.J.), 1256, 155-170 (2015-01-30)
Oral and cervical cancers are a growing global health problem that disproportionately impacts women and men living in the developing world. The high death rate in developing countries is largely due to the fact that these countries do not have
David Abookasis et al.
Journal of biomedical optics, 18(4), 045003-045003 (2013-04-06)
The authors' aim is to assess and quantitatively measure brain hemodynamic and morphological variations during closed-head injury (CHI) in mice using orthogonal diffuse near-infrared reflectance spectroscopy (o-DRS). CHI is a type of injury to the head that does not penetrate
Igor Nepluev et al.
Infection and immunity, 77(7), 3065-3074 (2009-05-20)
HgbA is the sole TonB-dependent receptor for hemoglobin (Hb) acquisition of Haemophilus ducreyi. Binding of Hb to HgbA is the initial step in heme acquisition from Hb. To better understand this step, we mutagenized hgbA by deletion of each of
Brendan R Scott et al.
Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 24(5), 722-730 (2014-08-16)
This study quantified the inter- and intra-test reliability of telemetric surface electromyography (EMG) and near infrared spectroscopy (NIRS) during resistance exercise. Twelve well-trained young men performed high-intensity back squat exercise (12 sets at 70-90% 1-repetition maximum) on two occasions, during
Hiroshi Hori et al.
Journal of inorganic biochemistry, 116, 53-54 (2012-09-27)
The effect of the quaternary structure change in deoxy-Hb on the electronic states of the ferrous high-spin heme was studied by multi-frequency electron paramagnetic resonance (MFEPR). We used a single-pass transmission-type EPR at 70-220 GHz and at 1.5K. We compared
Rebeca M Torrente-Rodríguez et al.
Journal of pharmaceutical and biomedical analysis, 129, 288-293 (2016-07-23)
A sensitive and rapid method for the determination of the clinically relevant biomarker human endoglin (CD105) in serum samples is presented, involving a magneto-actuated immunoassay and amperometric detection at disposable screen-printed carbon electrodes (SPCEs). Micro-sized magnetic particles were modified with
Pavla Fajtová et al.
PLoS neglected tropical diseases, 9(6), e0003827-e0003827 (2015-06-04)
Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl
Adam Dyer et al.
Bioscience reports, 35(4), doi:10-doi:10 (2015-07-17)
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria. As a spirochete, the morphology of the Borrelia cell envelope shares characteristics of both
Gloria Lusci et al.
Colloids and surfaces. B, Biointerfaces, 218, 112726-112726 (2022-08-02)
Biointerfaces are significantly affected by electrolytes according to the Hofmeister series. This work reports a systematic investigation on the effect of different metal chlorides, sodium and potassium bromides, iodides and thiocyanates, on the ESI/MS spectra of bovine serum albumin (BSA)
Vladimir M Turzhitsky et al.
Applied optics, 47(32), 6046-6057 (2008-11-13)
There has been significant interest in developing depth-selective optical interrogation of biological tissue in general and of superficial (e.g., mucosal) tissue in particular. We report an in vivo polarization-gating fiber-optic probe that obtains backscattering spectroscopic measurements from a range of
Tatiana Martini et al.
Caries research, 54(5-6), 466-474 (2020-11-11)
Saliva is the most important biological factor to protect against erosive tooth wear (ETW). Gastroesophageal reflux disease (GERD) patients have an increased risk of ETW due to the frequent presence of intrinsic acids in the oral cavity. Remarkably, not all
Jianxi Qu et al.
Micromachines, 12(2) (2021-01-28)
An accurate and rapid microflow cytometry-based agglutination immunoassay (MCIA) suitable for on-site antibody or antigen detection was proposed. In this study, quantitative C-reactive protein (CRP) detection was chosen as a model assay in order to demonstrate the detection principle. The
Yan-Liang Lai et al.
Redox biology, 15, 51-61 (2017-12-08)
Heme oxygenase (HO)-1 is an inducible stress response protein and well known to protect cells and tissues against injury. Despite its important function in cytoprotection against physiological stress, the role of HO-1 in embryonic stem cell (ESC) differentiation remains largely
Bensachee Pattamadilok et al.
Photodermatology, photoimmunology & photomedicine, 28(4), 213-215 (2012-09-29)
Tristimulus colorimetry and diffuse reflectance spectroscopy (DRS) are white-light skin reflectance techniques used to measure the intensity of skin pigmentation. The tristimulus colorimeter is an instrument that measures a perceived color and the DRS instrument measures biological chromophores of the
Lidai Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(15), 5759-5764 (2013-03-29)
Label-free functional imaging of single red blood cells (RBCs) in vivo holds the key to uncovering the fundamental mechanism of oxygen metabolism in cells. To this end, we developed single-RBC photoacoustic flowoxigraphy (FOG), which can image oxygen delivery from single
Chih-Hsin Wang et al.
International journal of molecular sciences, 22(13) (2021-07-03)
Chitosan, a polysaccharide derived from chitin, has excellent wound healing properties, including intrinsic antimicrobial and hemostatic activities. This study investigated the effectiveness of chitosan dressing and compared it with that of regular gauze dressing in controlling clinically surgical bleeding wounds
Rebekka Heitmar et al.
Investigative ophthalmology & visual science, 54(4), 2807-2811 (2013-03-16)
To establish the optimal flash settings for retinal vessel oxygen saturation parameters using dual-wavelength imaging in a multiethnic group. Twelve healthy young subjects (mean age 32 years [SD 7]; three Mediterranean, two South Asian, and seven Caucasian individuals) underwent retinal
Elise Abi-Khalil et al.
Biochimica et biophysica acta, 1850(9), 1930-1941 (2015-06-21)
Iron is an essential element for bacterial growth and virulence. Because of its limited bioavailability in the host, bacteria have adapted several strategies to acquire iron during infection. In the human opportunistic bacteria Bacillus cereus, a surface protein IlsA is
Yuko Shimamura et al.
Toxics, 10(1) (2022-01-21)
Hemoglobin (Hb) adducts have been used as biomarkers for the internal exposure to chemicals. Simultaneous exposure to chemicals that bond with the N-terminal valine of Hb to form adducts, such as glycidol, acrylamide, and glucose, may affect the formation of
Renu Sudhakar et al.
Microbiology spectrum, 10(3), e0278121-e0278121 (2022-05-27)
Despite a remarkable improvement in health care and continued drug discovery efforts, malaria control efforts are continuously challenged by the emergence of drug-resistant parasite strains. Given a long and risky development path of new drugs, repurposing existing drugs for the
Chiao-Wang Sun et al.
Circulation, 139(23), 2654-2663 (2019-03-25)
Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be essential for export of nitric oxide (NO) bioactivity by the red blood cell (RBC) to
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