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Showing 1-7 of 7 results for "HPA063797" within Papers

Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.

Han Zhu et al.

Developmental cell, 58(9), 727-743 (2023-04-12)

Pancreatic islet cells derived from human pluripotent stem cells hold great promise for modeling and treating diabetes. Differences between stem-cell-derived and primary islets remain, but molecular insights to inform improvements are limited. Here, we acquire single-cell transcriptomes and accessible chromatin

Charting cellular identity during human in vitro β-cell differentiation.

Adrian Veres et al.

Nature, 569(7756), 368-373 (2019-05-10)

In vitro differentiation of human stem cells can produce pancreatic β-cells; the loss of this insulin-secreting cell type underlies type 1 diabetes. Here, as a step towards understanding this differentiation process, we report the transcriptional profiling of more than 100,000

A functional vesicular monoamine transporter 1 (VMAT1) gene variant is associated with affect and the prevalence of anxiety, affective, and alcohol use disorders in a longitudinal population-representative birth cohort study.

Vaht M, et al.

The International Journal of Neuropsychopharmacology, 19(7) (2016)

Genetic polymorphism of vesicular monoamine transporter 1 gene (SLC18A1) in Emirati population.

Al Mutery A, et al.

International Journal of Genetics and Molecular Biology, 9(3), 16-20 (2017)

Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder.

Lohoff F W, et al.

Neuropsychopharmacology, 31(12), 2739-2739 (2006)

Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system.

Shenghui Liang et al.

Cell reports methods, 3(5), 100466-100466 (2023-06-16)

Orbital shaker-based suspension culture systems have been in widespread use for differentiating human pluripotent stem cell (hPSC)-derived pancreatic progenitors toward islet-like clusters during endocrine induction stages. However, reproducibility between experiments is hampered by variable degrees of cell loss in shaking

Association study of the vesicular monoamine transporter 1 (VMAT1) gene with autism in an Iranian population.

Noroozi R, et al.

Gene, 625, 10-14 (2017)

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