Merck
CN
Search Within

L1012

Applied Filters:
Keyword:'L1012'
Showing 1-30 of 369 results for "L1012" within Papers
Mei Yang et al.
Food chemistry, 177, 304-312 (2015-02-11)
It has been claimed that consumptions of Abrus cantoniensis (AC) and Abrus mollis (AM) as folk beverages and soups are good to cleanse liver toxicants and prevent liver diseases. There is scant information on the phytochemical profiles and antioxidant activities
Hiroshi Kubota et al.
Methods in molecular biology (Clifton, N.J.), 2155, 165-182 (2020-06-01)
Spermatogonial stem cells (SSCs) possess both self-renewal and differentiation abilities to sustain lifelong production of enormous numbers of spermatozoa in males. SSCs hold a unique position among tissue-specific stem cells in adults because of their ability to transmit the genetic
G Halperin et al.
Journal of chromatography. B, Biomedical sciences and applications, 742(2), 345-352 (2000-07-20)
We developed a method for the determination of serum 5alpha-cholestan-3beta-ol (cholestanol). The sterols were derivatized to the 4'-bromobenzenesulfonyl esters and heated in isopropanol. The cholesterol-4'-bromobenzenesulfonate was solvolyzed to cholesteryl isopropyl ether, but the derivatized cholestanol did not change and could
Christopher M Mulligan et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 69(7), 799-809 (2014-01-15)
Aging results in a redistribution of polyunsaturated fatty acids (PUFAs) in myocardial phospholipids. In particular, a selective loss of linoleic acid (18:2n6) with reciprocal increases of long-chain PUFAs (eg, arachidonic and docosahexaenoic acids) in the mitochondrial phospholipid cardiolipin correlates with
H T P Nguyen et al.
Nanotechnology, 26(25), 255101-255101 (2015-06-03)
The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients
E Zamora-Rojas et al.
Meat science, 95(3), 503-511 (2013-06-25)
A handheld micro-electro-mechanical system (MEMS) based spectrometer working in the near infrared region (NIR) (1600-2400nm) was evaluated for in-situ and non-destructive prediction of main fatty acids in Iberian pig (IP) carcasses. 110 IP carcasses were measured. Performance of the instrument
Ghazal Akbaridoust et al.
The Journal of dairy research, 82(3), 279-286 (2015-07-07)
The influence of different pasture-based feeding systems on fatty acids, organic acids and volatile organic flavour compounds in yoghurt was studied. Pasture is the main source of nutrients for dairy cows in many parts of the world, including southeast Australia.
Karmakar Ruma et al.
Pharmaceutical biology, 52(6), 665-676 (2014-03-19)
Endophytes colonizing medicinal plants are diverse, constituting a rich bioresource for novel natural products. Myrothecium sp. isolate M1-CA-102 was the most promising among the 16 Myrothecium isolates screened. The bioactive potential of the crude extract from the Calophyllum apetalum Willd.
Rebecca A Darling et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(1), R35-R43 (2014-04-25)
β-mercaptoacetate (MA) is a drug known to block mitochondrial oxidation of medium- and long-chain fatty acids (FAs) and to stimulate feeding. Because MA-induced feeding is vagally dependent, it has been assumed that the feeding response is mediated by MA's antimetabolic
Hiroo Kawajiri et al.
Archives of biochemistry and biophysics, 398(1), 51-60 (2002-01-29)
Previous studies in our laboratory revealed a high expression of 15-lipoxygenase-1 in human colorectal carcinomas, suggesting the importance of lipoxygenase in colorectal tumor development. In this report, we have investigated the metabolism of arachidonic and linoleic acid by intestinal tissues
Aurelie Vivares et al.
Xenobiotica; the fate of foreign compounds in biological systems, 45(1), 29-44 (2014-07-30)
1. The quantitative prediction of the pharmacokinetic parameters of a drug from data obtained using human in vitro systems remains a significant challenge i.e. prediction of metabolic clearance in humans and estimation of the relative contribution of enzymes involved in
Eu Jin Lim et al.
The Journal of general virology, 95(Pt 10), 2204-2215 (2014-06-29)
Chronic hepatitis C virus (HCV) infection results in progressive liver fibrosis leading to cirrhosis and liver cancer. The mechanism for this remains unclear but hepatocyte apoptosis is thought to play a major role. Hepatocyte apoptosis in human liver tissue was
Sandra A Jacobs et al.
Cell transplantation, 23(9), 1099-1110 (2013-04-09)
Human multipotent adult progenitor cells (hMAPCs) are isolated from bone marrow with a more extensive expansion capacity compared to human mesenchymal stem cells (hMSCs) and with the ability to differentiate into endothelium. Like hMSCs, hMAPCs inhibit T-cell proliferation induced by
Guillermo Marcial et al.
Journal of ethnopharmacology, 155(2), 1125-1133 (2014-07-06)
The aerial parts of Lippia integrifolia (Gris.) Hieronymus (Verbenaceae), known as incayuyo, are used by the peasant population of Argentina for treatment of diseases related to a gastrointestinal system, mainly for inflammation of the stomach and have also been included
Rie Ouchi et al.
Cell metabolism, 30(2), 374-384 (2019-06-04)
Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible method to derive multi-cellular human liver organoids
Chantal Cossette et al.
Biochemical pharmacology, 96(3), 247-255 (2015-06-03)
The 5-lipoxygenase product 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is the most powerful human eosinophil chemoattractant among lipid mediators and could play a major pathophysiological role in eosinophilic diseases such as asthma. Its actions are mediated by the OXE receptor, orthologs of which
Felix Aladedunye et al.
Food chemistry, 141(3), 2373-2378 (2013-07-23)
The influence of linoleic acid content and tocopherol isomeric composition on the frying performance of high oleic sunflower oil was evaluated during a 14-day restaurant style frying operation. At equal linoleic acid content, no significant difference was observed between high
Abdulselam Ertas et al.
Pharmaceutical biology, 53(3), 334-339 (2014-10-22)
In Turkey, Veronica species (Plantaginaceae) have been used as a diuretic and for wound healing in traditional medicine. To examine the fatty acid and essential oil profiles, the antioxidant, anticholinesterase, antimicrobial, and DNA damage effects of Veronica thymoides P.H. Davis
Masahiko Yano et al.
Antimicrobial agents and chemotherapy, 51(6), 2016-2027 (2007-04-11)
To date, only a limited number of studies have reported finding an influence of ordinary nutrients on hepatitis C virus (HCV) RNA replication. However, the effects of other nutrients on HCV RNA replication remain largely unknown. We recently developed a
K Bougis et al.
The European physical journal. E, Soft matter, 38(7), 78-78 (2015-07-16)
Structure and interactions stabilising the lamellar stack of mixed lipid bilayers in their fluid state are investigated by means of small-angle X-ray scattering. The (electrically neutral) bilayers are composed of a mixtures of lecithin, a zwitterionic phospholipid, and Simulsol, a
A P Moloney et al.
Meat science, 95(3), 608-615 (2013-06-29)
The effect of type of silage offered to beef heifers during the finishing period on aspects of beef quality was determined. In two experiments, a diet based on grass silage (GS) was compared with a diet based on maize silage
James A Emery et al.
PloS one, 8(2), e57463-e57463 (2013-03-06)
It is generally accepted that, in vertebrates, omega-3 (n-3) and omega-6 (n-6) poly-unsaturated fatty acids (PUFA) compete for Δ-6 desaturase enzyme in order to be bioconverted into long-chain PUFA (LC-PUFA). However, recent studies into teleost fatty acid metabolism suggest that
Amit Kumar et al.
Nutrition & metabolism, 12, 8-8 (2015-03-19)
The hallmark of Type 2 diabetes (T2D) is hyperglycemia, although there are multiple other metabolic abnormalities that occur with T2D, including insulin resistance and dyslipidemia. To advance T2D prevention and develop targeted therapies for its treatment, a greater understanding of
Shohreh Nikoo et al.
Molecular human reproduction, 20(9), 905-918 (2014-06-19)
Retrograde flow of menstrual blood cells during menstruation is considered as the dominant theory for the development of endometriosis. Moreover, current evidence suggests that endometrial-derived stem cells are key players in the pathogenesis of endometriosis. In particular, endometrial stromal stem
Christina Papaemmanouil et al.
Journal of agricultural and food chemistry, 63(22), 5381-5387 (2015-05-20)
We report a rapid, direct, and unequivocal spin-chromatographic separation and identification of minor components in the lipid fraction of milk and common dairy products with the use of selective one-dimensional (1D) total correlation spectroscopy (TOCSY) nuclear magnetic resonance (NMR) experiments.
Yaping Zhang et al.
Journal of Cancer, 5(8), 706-714 (2014-09-27)
Lung cancer (LC) is the deadliest cancer, with earlier stage patients having a better opportunity of long-term survival. The goal of this study is to screen less-invasive and efficient biomarkers for early detection of non-small cell LC (NSCLC). We performed
Ilse Reinders et al.
The Journal of nutrition, 145(1), 105-112 (2014-10-31)
Muscle mass, intermuscular adipose tissue, and strength are important indicators of physical function. Dietary fatty acids (FAs) have been associated with muscle parameters such as larger size and higher strength, but large, population-based longitudinal data in older adults who are
Margit M McGowan et al.
Breast cancer research and treatment, 138(1), 175-183 (2013-02-19)
Conjugated linoleic acid (CLA) is widely used as a "nutraceutical" for weight loss. CLA has anticancer effects in preclinical models, and we demonstrated in vitro that this can be attributed to the suppression of fatty acid (FA) synthesis. We tested
Wan Mohd Nuzul Hakimi Salleh et al.
Natural product communications, 10(8), 1465-1468 (2015-10-06)
The essential oils of Cinnamomum griffithii and C. macrocarpum were analyzed by GC and GC-MS and evaluated for their antioxidant and anticholinesterase activities. The essential oils of leaf and bark of C. grffithii were characterized by the presence of 30
Karen Kleberg et al.
The Journal of physiology, 593(8), 2097-2109 (2015-02-03)
Sensing of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and behavioural responses. However, the exact physiological pathways linking intestinal fat sensing to food intake and the activation of brain circuits remain to be identified. In this
Page 1 of 13