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HPLC Analysis of PEG g006200

HPLC Analysis of PEG on Two Zenix® SEC-300 Columns in Tandem

HPLC Analysis of Vitamins B1 B6 B12

HPLC Analysis of Vitamins B1, B6 and B12 using Ascentis® Express RP-Amide

HPLC Tips & Tricks: Mobile Phase Preparation Part 2 - Buffers

Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.

Workflow for the Analysis of Polysorbate 80 in Erbitux® Formulation

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

LC/MS/MS Analysis of Vitamins B1 and B6 on Ascentis® Express OH5

Separation of Pyridoxine Hydrochloride (B6), analytical standard; Thiamine Hydrochloride (B1), analytical standard

LC/MS Analysis of Opioid Glucuronide Metabolites in Urine on Ascentis® Express F5 after Solid Phase Extraction (SPE) using Supel™-Select HLB

HPLC Assay and Impurity Profiling Methods for Safinamide and Safinamide Related Impurities

A sensitive and reproducible HPLC-DAD method for the purity analysis of safinamide and its related impurities using an Ascentis® Express C8 column (150 x 4.6 mm, 5 μm), meeting the system suitability criteria.

Determination of Quinine in Tonic Water and Caffeine in Coffee and Cola Drinks Using TLC-MS

HPTLC–MS analysis of quinine in tonic water and caffeine in coffee and cola drinks. Tonic and cola drinks decarbonized through ultrasonication, and coffee extracted through PTFE filter.

Thin Layer Chromatography Identification Test for Dextromethorphan following European Pharmacopeia Monograph on Silica Gel G 254 Plates

Silica gel G 254 plates are suitable for analysis of Dextromethorphan following the European pharmacopeia monograph.

Determination of Ephedrine HCl and Pseudoephedrine HCl in Xiao’er Kechuanling Oral Solution with Purospher® STAR RP-18e column

HPLC method to analyze ephedrine HCl and pseudoephedrine HCl in traditional Chinese medicine (TCM) with a Purospher® RP-18e colμmn to report chromatographic data, linearity, specificity and repeatability and LOD and LOQ.

Detection and Determination of Caffeine, Taurine and Arginine in Shampoos by HPTLC

The modern thin-layer chromatography (TLC) offers advantages also in the field of cosmetics to quickly and simultaneously analyze samples with densitometric detection.

Fast and high-resolution Analysis of Intact Therapeutic Monoclonal Antibody Trastuzumab using BIOshell™ A400 Protein C4 Column

Optimization of a Reversed-Phase Liquid Chromatographic (RP-LC) method for the intact analysis of a therapeutic monoclonal antibody, trastuzumab, using a BIOshell™ A400 Protein C4 column.

Analysis of Remdesivir and other Antiviral Drugs Using LC-MS/MS

We present a fast and robust HPLC-MS/MS method that can be used for Remdesivir and three structural antiviral analogues

The Importance of Filtration in Optimizing (U)HPLC and LC-MS Performance

Learn how filter selection and sample and mobile phase filtration impact HPLC back pressure and column lifetime.

Determination of Tramadol in Urine using LC-MS/MS

This article presents an LC-MS/MS method for the determination of tramadol in urine samples using reversed-phase LC-MS/MS aided by isotope internal standards.

Ethyl Acetate

We offer a variety of ethyl acetate products suitable for applications including GC, HPLC, UHPLC, and LC-MS. We also supply multiple options for anhydrous ethyl acetate and ACS grade ethyl acetate.

UHPLC Analysis of Cannabinoids on Ascentis Express C18

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

Separation of Organic Acids with 100% aqueous mobile phase using an Ascentis^® Express AQ-C18 HPLC Column

A new RP-HPLC method is proposed for the determination of organic acids in 100% aqueous mobile phase using an Ascentis® Express AQ-C18 column

Determination of Ethyl Glucuronide and Ethyl Sulfate in Urine using LC-MS/MS

This study is aimed at developing and validating an LC-ESI-ion trap-MS/MS method for identification and quantification of ethyl glucuronide (EtG) and ethyl sulfate (EtS) as ethanol biomarkers for urine analysis.

Sildenafil Citrate USP Method Using HPTLC Plates for the Limit of Imidazole Test

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

BIOshell™ IgG 1000 Å C4 UHPLC Column for Improved Biomacromolecule Separations

Difluoroacetic Acid as an Effective Mobile Phase Modifier for the LC-UV/MS Analysis of Proteins

The article describes the use of difluoroacetic acid (DFA) as an effective alternative to acid modifiers, formic acid (FA) and trifluoroacetic acid (TFA) in the LC-UV/MS analysis of proteins.