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Showing 1-30 of 322 results for "M0200000" within Papers
Fengzhen Wang et al.
Journal of liposome research, 24(3), 171-181 (2014-03-13)
The purpose of the present study was to optimize methazolamide (MTZ)-loaded solid lipid nanoparticles (SLNs) which were used as topical eye drops by evaluating the relationship between design factors and experimental data. A three factor, three-level Box-Behnken design (BBD) was
Ting He et al.
Molecular and cellular endocrinology, 402, 13-20 (2014-12-30)
Resveratrol (RSV) is reported to have renoprotective activity against diabetic nephropathy, while the mechanisms underlying its function have not been fully elucidated. In this study, we investigate the effect and related mechanism of RSV against high glucose-induced epithelial to mesenchymal
Adolfo Maria Tambella et al.
Veterinary surgery : VS, 43(6), 726-733 (2014-02-04)
To determine the efficacy of topical application of the autologous platelet gel (PG) in canine chronic protracted decubital ulcers. Prospective, randomized, blind controlled clinical trial. Dogs (n = 18) with bilateral chronic wounds caused by protracted decubitus ulcers. For each dog, wound
Joy Schramm-Baxter et al.
Journal of controlled release : official journal of the Controlled Release Society, 97(3), 527-535 (2004-06-24)
Jet injection is a needle-free drug delivery method in which a high-speed stream of fluid impacts the skin and delivers drugs. Although a number of jet injectors are commercially available, especially for insulin delivery, a quantitative understanding of the energetics
M M Santana et al.
Mikrobiologiia, 81(6), 720-725 (2013-04-25)
Desulfovibrio vulgaris Hildenborough genome presents a phosphotransferase system putatively involved in the transport of carbohydrates. However, utilization of sugars by this sulfate-reducing bacterium has never been reported. Herein, we have observed proliferation of D. vulgaris Hildenborough with some carbohydrates, in
Georg Bauer et al.
Carcinogenesis, 35(7), 1582-1591 (2014-03-26)
Malignant transformation of gastric epithelial cells by chronic Helicobacter pylori infection is caused by several mechanisms including attraction of reactive oxygen species (ROS)-producing neutrophils and cytotoxin-associated antigen A-mediated dysplastic alterations. Here we show that H.pylori protects transformed cells from ROS-mediated
Emma C Hansson et al.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 46(4), 699-705 (2014-02-01)
Ticagrelor reduces thrombotic events compared with clopidogrel in patients with acute coronary syndrome, but may also increase bleeding complications. Coronary artery bypass grafting (CABG)-related bleeding complications have not previously been compared in clopidogrel and ticagrelor-treated patients outside the controlled environment
Eman F Ahmed et al.
Surgical infections, 15(4), 404-411 (2014-05-13)
Staphylococcus aureus (S. aureus) is isolated frequently from surgical site infections and other soft tissue infections. There are limited data examining the prevalence of methicillin resistant S. aureus (MRSA) among Egyptian patients after surgery. The current study determined the prevalence
David S Wishart et al.
Nucleic acids research, 37(Database issue), D603-D610 (2008-10-28)
The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Since its first release in 2007, the
B Berchtold et al.
Journal of dairy science, 97(8), 4886-4896 (2014-06-03)
Bovine mastitis is a frequent problem in Swiss dairy herds. One of the main pathogens causing significant economic loss is Staphylococcus aureus. Various Staph. aureus genotypes with different biological properties have been described. Genotype B (GTB) of Staph. aureus was
Abel Wakai et al.
The Cochrane database of systematic reviews, 8(8), CD001049-CD001049 (2013-08-07)
Mannitol is sometimes effective in reversing acute brain swelling, but its effectiveness in the ongoing management of severe head injury remains unclear. There is evidence that, in prolonged dosage, mannitol may pass from the blood into the brain, where it
Charudharshini Srinivasan et al.
International journal of pharmaceutics, 481(1-2), 104-113 (2015-02-01)
Drug shortages and recalls are often caused due to particulate growth in parenteral products and can have serious clinical implications. Root cause analysis of such recalls and shortages may arise due to insufficient understanding of process, formulations issues and environmental
Yasuo Uchida et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(10), 1719-1726 (2014-07-26)
The purpose of this study was to demonstrate experimentally that alterations of in vivo transporter function at the blood-brain barrier (BBB) in disease and during pharmacotherapy can be reconstructed from in vitro data based on our established pharmacoproteomic concept of
Gui-Xin He et al.
Journal of medical microbiology, 63(Pt 5), 735-741 (2014-03-04)
We isolated a total of 653 strains from 64 community environmental samples in Massachusetts, USA. Among these isolates, 9.65 % (63 strains) were benzalkonium chloride (BC)-resistant staphylococci. All BC-resistant strains were collected from surfaces upon which antibacterial wipes or antibacterial sprays
Vibeke Backer et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(4), 411-416 (2014-01-24)
Ongoing airway inflammation measured by fractional exhaled nitric oxide (FENO) and airway hyperresponsiveness (AHR) to mannitol are associated in selected asthma patients, but no evidence exists of this association in unselected asthma patients. The aim was to investigate the association
Nan Hu et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 306(10), R761-R771 (2014-03-14)
Hydrogen sulfide (H2S) is a toxic gas now being recognized as an endogenous signaling molecule in multiple organ systems, in particular, the cardiovascular system. H2S is known to regulate cardiac function and protect against ischemic injury. However, little information is
Yih-Chih Chan et al.
The Journal of allergy and clinical immunology, 134(6), 1394-1401 (2014-08-13)
Naturally occurring IgE-specific IgG autoantibodies have been identified in patients with asthma and other diseases, but their spectrum of functions is poorly understood. Address the hypothesis that: (i) IgG anti-IgE autoantibodies are detectable in the serum of all subjects but
Juan I Martínez-Salamanca et al.
The journal of sexual medicine, 11(5), 1182-1192 (2014-05-31)
The efficacy of oral pharmacotherapy for erectile dysfunction (ED) (i.e., type 5 phosphodiesterase[PDE5] inhibitors) is significantly reduced in diabetic patients. Nebivolol is a selective β1-blocker used for treatinghy pertension that has been shown to increase the efficacy of sildenafil to
Celeste B Burness et al.
Drugs, 72(10), 1411-1421 (2012-07-05)
Mannitol dry powder for inhalation has been developed for the treatment of patients with cystic fibrosis. Two randomized, double-blind, multinational, 26-week, phase III trials (CF-301 and CF-302) examined the efficacy of inhaled dry powder mannitol in patients aged ≥ 6
Anke Sass et al.
Drug development and industrial pharmacy, 40(6), 749-757 (2013-04-20)
The spray-drying behaviour of 16 water-miscible organic solvents on a bench-scale machine (Büchi B290 with inert loop) was determined under mild-to-moderate process conditions, namely inlet gas temperature of 130 °C and liquid feed flow rate of ≤3 mL/min. The solvents with boiling
Tobias Eisenberg et al.
BMC microbiology, 15, 42-42 (2015-04-19)
The zoonotic bacterium Corynebacterium ulcerans may be pathogenic both in humans and animals: toxigenic strains can cause diphtheria or diphtheria-like disease in humans via diphtheria toxin, while strains producing the dermonecrotic exotoxin phospholipase D may lead to caseous lymphadenitis primarily
Badal C Saha et al.
Applied microbiology and biotechnology, 89(4), 879-891 (2010-11-11)
Mannitol, a naturally occurring polyol (sugar alcohol), is widely used in the food, pharmaceutical, medical, and chemical industries. The production of mannitol by fermentation has become attractive because of the problems associated with its production chemically. A number of homo-
Vincenzo Lionetti et al.
Phytochemistry, 112, 188-194 (2014-08-19)
Cell adhesion occurs primarily at the level of middle lamella which is mainly composed by pectin polysaccharides. These can be degraded by cell wall degrading enzymes (CWDEs) during developmental processes to allow a controlled separation of plant cells. Extensive cell
K H Polderman et al.
Critical care medicine, 31(2), 584-590 (2003-02-11)
Mannitol is widely used in hospitals worldwide to treat patients with high intracranial pressure and/or cerebral edema. One of the mechanisms by which mannitol is thought to affect intracranial pressure is by increasing the patient's serum osmolarity, but not the
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bet 1. Rhabdomyolysis and the use of sodium bicarbonate and/or mannitol.
Rachel Thomas
Emergency medicine journal : EMJ, 27(4), 305-308 (2010-04-14)
Maria del Nogal et al.
The international journal of biochemistry & cell biology, 54, 98-110 (2014-07-22)
Hyperglycemia is involved in the diabetic complication of different organs and can elevate serum osmolarity. Here, we tested whether hyperosmolarity promoted by high glucose levels induces cellular senescence in renal cells. We treated Wistar rats with streptozotocin to induce diabetes
M Hogan et al.
Anaesthesia, 70(5), 563-570 (2015-02-19)
Cardiac surgery and cardiopulmonary bypass are associated with haemodilution, activation of haemostasis and blood transfusion. We undertook a randomised controlled trial that included 53 patients in order to compare autotransfusion of residual cardiopulmonary bypass blood with residual blood concentrated using
Yub Raj Neupane et al.
International journal of pharmaceutics, 477(1-2), 601-612 (2014-12-03)
The aim of this study was to design and fabricate nanostructured lipid carrier (NLC) for the potential oral delivery of decitabine (DCB). NLC was prepared by cold homogenization technique and optimized by the Box-Behnken experimental design. It was further characterized
Tao Chen et al.
Asian Pacific journal of allergy and immunology, 32(4), 345-353 (2014-12-30)
The intestinal tract plays an important role in food allergy and the intestinal mucosa barrier is critical for maintenance of its function. The underlying mechanisms of how food allergens modulate the intestinal permeability in inducing intestinal food allergy remain elusive.
Kerin L Tyrrell et al.
Journal of clinical microbiology, 51(9), 3094-3096 (2013-06-28)
Cycloserine-cefoxitin fructose agar (CCFA), CCFA with horse blood and taurocholate (CCFA-HT), and cycloserine-cefoxitin mannitol broth with taurocholate and lysozyme (CCMB-TAL) were compared for recovery of Clostridium difficile from 120 stool specimens. Compared to CCFA, CCFA-HT enhanced C. difficile growth and
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