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Showing 1-30 of 44 results for "M1640" within Papers
Jessica X Jia et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 11(3), 45-62 (2008-09-20)
Oral drug development had been hindered by the bioavailability issue despite vast market popularity. Lipid excipients had shown to enhance bioavailability of a number of reformulated hydrophobic oral drugs, yet the underlying mechanisms of action by lipids are still unclear.
P Glynn
The Biochemical journal, 344 Pt 3, 625-631 (1999-12-10)
Neuropathy target esterase (NTE) is an integral membrane protein present in all neurons and in some non-neural-cell types of vertebrates. Recent data indicate that NTE is involved in a cell-signalling pathway controlling interactions between neurons and accessory glial cells in
A López-López et al.
Journal of chromatography. B, Biomedical sciences and applications, 760(1), 97-105 (2001-08-28)
An alternative method to determine the sn-2 monopalmitin in infant formulas was developed and validated. This method offers many advantages over the traditional methods. It follows the official method in the first steps, purification of the fat or oil through
Cecilio Carrera Sánchez et al.
Langmuir : the ACS journal of surfaces and colloids, 20(15), 6327-6334 (2004-07-14)
In this work, we have used different and complementary interfacial techniques (surface film balance, Brewster angle microscopy, and interfacial shear rheology) to analyze the static (structure, topography, reflectivity, miscibility, and interactions) and flow characteristics (surface shear characteristics) of beta-casein and
Knut-Egil Løkling et al.
Magnetic resonance in medicine, 51(4), 688-696 (2004-04-06)
The use of paramagnetic pH-sensitive liposomes was recently suggested as a new approach for monitoring pathologic changes in pH by MRI. Such liposomes must be stable in blood and selectively release the encapsulated paramagnetic agent when exposed to lower pH
J M Brewer et al.
Immunology, 75(4), 570-575 (1992-04-01)
The ability of non-ionic surfactant vesicles (NISV) to enhance antibody production against bovine serum albumin (BSA) was compared with Freund's complete adjuvant (FCA), in the BALB/c mouse. Two subcutaneous inoculations with NISV entrapped BSA induced antibody levels comparable to, and
Surapun Tepaamorndech et al.
The FEBS journal, 283(2), 378-394 (2015-11-03)
Mice deficient for zinc transporter 7 protein (ZnT7) are mildly zinc deficient with low body weight gain and body fat accumulation. To investigate the underlying mechanism of ZnT7 deficiency in body adiposity, we examined fatty acid composition and insulin sensitivity
A W Tumaney et al.
The Journal of biological chemistry, 276(14), 10847-10852 (2001-04-03)
Biosynthesis of diacylglycerols in plants occurs mainly through the acylation of lysophosphatidic acid in the microsomal membranes. Here we describe the first identification of diacylglycerol biosynthetic activity in the soluble fraction of developing oilseeds. This activity was NaF-insensitive and acyl-CoA-dependent.
Z Chao et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 16(2), 97-99 (1991-02-01)
Nine compounds were isolated from the pericarp of T. rosthornii and identified on the basis of spectral data to be palmitic acid, lignoceric acid, cerotic acid, montanic acid, melissic acid, L-(-)-alpha-monopalmitin, delta 7-stigmastenol, delta 7-stigmastenone-3 and delta 7-stigmatenol-3-beta-D-glucopyranoside. All but
Juan M Rodríguez Patino et al.
Langmuir : the ACS journal of surfaces and colloids, 20(11), 4515-4522 (2005-06-23)
In this work we have analyzed the structural and topographical characteristics of mixed monolayers formed by an adsorbed whey protein isolate (WPI) and a spread monoglyceride monolayer (monopalmitin or monoolein) on the previously adsorbed protein film. Measurements of the surface
Jessica A Conlan et al.
PeerJ, 6, e4239-e4239 (2018-02-07)
Scleractinian corals are colonial organisms comprising multiple physiologically integrated polyps and branches. Colonialism in corals is highly beneficial, and allows a single colony to undergo several life processes at once through physiological integration and compartmentalised functioning. Elucidating differences in the
T Okayasu et al.
Biochimica et biophysica acta, 876(1), 58-64 (1986-03-21)
The metabolic fate of 1-O-[3H]alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF-acether) upon interaction with primary cultured adult rat hepatocytes was investigated. [3H]PAF-acether was transformed time-dependently into [3H]lyso-PAF-acether, 1-O-[3H]alkylglycerol and finally converted to 3H-labeled fatty aldehyde. 1-O-[3H]Alkyl-2-acyl-sn-glycero-3-phosphocholine (alkylacyl-GPC) was formed after a long incubation time and
Chang Li et al.
Journal of agricultural and food chemistry, 63(44), 9850-9854 (2015-10-20)
The capacities of six antioxidants to inhibit the formation of 3-monochloropropane-1,2 diol (3-MCPD) esters were examined in this study. Inhibitory capacities of the antioxidants were investigated both in chemical models containing the precursors (tripalmitoyl glycerol, 1,2-dipalmitoyl-sn-glycerol, monopalmitoyl glycerol, and sodium
Juan M Rodríguez Patino et al.
Biomacromolecules, 7(9), 2661-2670 (2006-09-12)
In this work, we have analyzed the structural, topographical, and surface dilatational characteristics of pure beta-lactoglobulin adsorbed films and the effect of the self-assembly of monoglycerides (monopalmitin or monoolein) in beta-lactoglobulin films at the air-water interface. Measurements were performed in
Yuyi Shen et al.
Langmuir : the ACS journal of surfaces and colloids, 24(18), 10035-10040 (2008-08-23)
A low cost food grade emulsifier (a mixture of monoglycerides, diglycerides, and sodium stearoyl lactylate) in combination with polyethylene glycol-40 stearate (PEG-40S) was used as an alternative to pure saturated phospholipids to form the thin shell of a microbubble. To
Jessica A Conlan et al.
PloS one, 12(11), e0188568-e0188568 (2017-11-29)
Heterotrophic feeding in newly-settled coral planulae can potentially improve survivorship and accelerate early development in some species; however, an optimal diet to facilitate this does not currently exist. This study evaluated the efficacy of three heterotrophic feeding regimes (enriched rotifers
P Trumbo et al.
Lipids, 22(12), 1009-1015 (1987-12-01)
Palmitoyl glycerol is toxic when fed to mice, but the toxicity is alleviated by supplementing the toxic diet with 2-4% oleate or linoleate at the expense of sucrose. Lipid and fatty acid composition of lymph and plasma were studied in
P R Trumbo et al.
The Journal of nutrition, 117(10), 1780-1787 (1987-10-01)
Mice given propylthiouracil, a thyroid inhibitor, and fed a diet containing a nontoxic level of rac-1(3)-palmitoyl glycerol showed the hypothermia and mortality expected for a toxic dose, but did not show these signs when linoleate or oleate was added to
Nicola J Commander et al.
Genetic vaccines and therapy, 8, 5-5 (2010-07-20)
We have previously demonstrated protective efficacy against B. melitensis using formulations of naked DNA vaccines encoding genes ialB and omp25. The present study was undertaken to further understand the immune response generated by the protective vaccination regimens and to evaluate
Danielle M Schwartz et al.
Journal of lipid research, 48(11), 2514-2520 (2007-08-25)
We have developed a reliable, rapid, and economical assay for the quantification of triacylglycerol (TG) in cells and animal tissues. In a few hours, this assay quantifies microgram amounts of TG from tens or even hundreds of samples. The protocol
I Kanesaka et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 57(8), 1621-1626 (2001-07-27)
The infrared spectra of 1-monopalmitin- or 1-monostearin-water systems in the gel phase were observed at room temperature. In both systems the infrared intensities of the bands parallel and perpendicular to the paraffin chain are relatively reduced and enhanced, respectively, on
Marta Cejudo Fernández et al.
The journal of physical chemistry. B, 110(47), 24212-24221 (2006-11-28)
In this work we have analyzed the penetration of betalactoglobulin into a monoglyceride monolayer (monopalmitin or monoolein) spread at the air-water interface and its effects on the structural, dilatational, and topographical characteristics of mixed films. Dynamic tensiometry, surface film balance
Eugenia Marbach-Breitrück et al.
Antioxidants & redox signaling, 32(1), 1-17 (2019-10-24)
Aims: Most mammalian genomes involve several genes encoding for functionally distinct arachidonate lipoxygenase (ALOX isoforms). Proinflammatory leukotrienes are formed
G Lyubachevskaya et al.
Lipids, 35(12), 1353-1358 (2001-02-24)
In the metabolism of triacylglycerol (TG)-rich lipoproteins, 2-monoacylglycerols (2-MG) are produced by lipoprotein lipase (LPL) hydrolysis of TG. The metabolic fate of 2-MG is not known with certainty. 2-MG that accumulate on the chylomicra surface have been proposed to isomerize
Jean-Paul Douliez
Langmuir : the ACS journal of surfaces and colloids, 20(5), 1543-1550 (2005-04-02)
The phase behavior of mixtures of palmitic acid (PA) and 1-monohexadecanoyl-rac-glycerol, palmitin, was studied by phase contrast microscopy and deuterium solid-state NMR. At pH 5, mixtures remained precipitated as lumps in solution. The NMR spectrum of the perdeuterated PA (PAd31)
Tomoko Konishi et al.
British journal of pharmacology, 143(3), 379-387 (2004-09-08)
Extracts of bitter melon, soybean, dokudami and welsh onion by 40% methanol increased the accumulation of rhodamine-123 by Caco-2 cells, suggesting that these extracts inhibited P-glycoprotein (P-gp). The extract of bitter melon was separated in a tC18 cartridge column and
Marianne van Tienhoven et al.
The Journal of biological chemistry, 277(23), 20942-20948 (2002-04-03)
A neuronal membrane protein, neuropathy target esterase (NTE), reacts with those organophosphates that initiate a syndrome of axonal degeneration. NTE has homologues in Drosophila and yeast and is detected in vitro by assays with a non-physiological ester substrate, phenyl valerate.
Nuria Prim et al.
Colloids and surfaces. B, Biointerfaces, 52(2), 138-142 (2006-07-11)
Using the Langmuir-Blodgett technique we prepared substrate supported well-defined lipid/phospholipid (1-mono-palmitoyl-rac-glycerol (MPG)/l,2-dipalmitoyl-sn-glycerol-3-phosphocholine (DPPC)) bilayers in which the MPG lipid leaflet was exposed to the aqueous phase. Hydrolysis of MPG performed by Candida rugosa lipase (CRL) on the upper MPG layer
S R Siddhanti et al.
The Journal of nutrition, 117(10), 1671-1675 (1987-10-01)
Adult and weanling mice kept at low ambient temperatures show an increased sensitivity to the toxicity of dietary rac-1(3)-palmitoyl glycerol. When fed the palmitoyl glycerol, mice less than 6 wk old show a pronounced hypothermia that is prevented by adding
J M Rodríguez Patino et al.
Journal of agricultural and food chemistry, 47(12), 4998-5008 (1999-12-22)
The surface pressure (pi)-area (A) isotherms and Brewster angle microscopy (BAM) images of monopalmitin and beta-casein mixed films spread on buffered water at pHs 5 and 7 and at 20 degrees C were determined as a function of the mass
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