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Showing 1-30 of 565 results for "M8429" within Papers
Tatjana Orct et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 28(4), 701-712 (2015-05-08)
Detoxification of mercury (Hg) with selenium (Se) in the early postnatal period with regard to the expression of metallothionein protein (MT), essential element status, and lipid peroxidation level in tissues has not been studied. Seven-day-old Wistar pups were orally pretreated
S A Kim et al.
Journal of food protection, 78(12), 2233-2239 (2015-11-29)
This study investigated changes in the microbial composition of microbrewed beer during the manufacturing processes and identified potential microbial hazards, effective critical quality control points, and potential contamination routes. Comprehensive quantitative (aerobic plate count, lactic acid bacteria, fungi, acetic acid
Elisabeth Lenz et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 44-52 (2015-07-22)
Co-amorphous drug formulations provide the possibility to stabilize a drug in its amorphous form by interactions with low molecular weight compounds, e.g. amino acids. Recent studies have shown the feasibility of spray drying as a technique to manufacture co-amorphous indomethacin-arginine
Katrine B Buggeskov et al.
Trials, 14, 30-30 (2013-02-01)
Five to thirty percent of patients undergoing cardiac surgery present with chronic obstructive pulmonary disease (COPD) and have a 2- to 10-fold higher 30-day mortality risk. Cardiopulmonary bypass (CPB) creates a whole body systemic inflammatory response syndrome (SIRS) that could
Enrico Velardi et al.
The Journal of experimental medicine, 211(12), 2341-2349 (2014-10-22)
Paradoxical to its importance for generating a diverse T cell repertoire, thymic function progressively declines throughout life. This process has been at least partially attributed to the effects of sex steroids, and their removal promotes enhanced thymopoiesis and recovery from
M Ellaurie et al.
The Pediatric infectious disease journal, 11(4), 286-289 (1992-04-01)
Neopterin concentrations in 50 children with human immunodeficiency virus infection were correlated with disease course. The neopterin concentrations ranged from 4 to 70 nM with a mean of 34.7 +/- 25.1 (SD) nM compared with a mean of 6.1 +/-
Rong Yang et al.
Molecular medicine reports, 10(4), 1992-1998 (2014-07-23)
Myocardial fibrosis and excessive proliferation of cardiac fibroblasts (CFs) contribute to diabetic cardiomyopathy (DCM). However, the underlying mechanism is still not completely clear. The aim of this study was to investigate the relationship between high-glucose treatment and the expression of
Kazuhisa Ozeki et al.
International journal of pharmaceutics, 495(2), 963-971 (2015-09-22)
In a transcellular transport study, the apparent permeability coefficient (Papp) of a compound is evaluated using the range by which the amount of compound accumulated on the receiver side is assumed to be proportional to time. However, the time profile
Aravind Ravindran et al.
MicrobiologyOpen, 4(4), 553-573 (2015-05-06)
Pseudomonas syringae pv. syringae is a common plant-associated bacterium that causes diseases of both monocot and dicot plants worldwide. To help delineate traits critical to adaptation and survival in the plant environment, we generated complete genome sequences of P. syringae
Naotaka Nishimura et al.
PeerJ, 2, e349-e349 (2014-04-26)
It has been reported that the expression of TMEM65 is regulated by steroid receptor RNA activator (SRA). To date, however, the localization and function of TMEM65 remained unknown. We analyzed the intracellular localization of TMEM65. Immunoblot and immunostaining analysis revealed
Rafael Yaari et al.
Plant molecular biology, 88(4-5), 387-400 (2015-05-07)
DNA methylation has a crucial role in plant development regulating gene expression and silencing of transposable elements. Maintenance DNA methylation in plants occurs at symmetrical (m)CG and (m)CHG contexts ((m) = methylated) and is maintained by DNA METHYLTRANSFERASE 1 (MET1) and CHROMOMETHYLASE
Hannah E Smith et al.
The Journal of nutrition, 144(12), 2059-2065 (2014-11-21)
Environmental enteropathy (EE) is subclinical, diffuse villous atrophy characterized by T cell infiltration of the small intestinal mucosa associated with nutrient malabsorption and stunting. EE is assessed by the lactulose:mannitol (L:M) test, whereby nonmetabolized sugars are ingested and quantified in
Nabil Souihi et al.
International journal of pharmaceutics, 484(1-2), 192-206 (2015-02-24)
In this study, the roll compaction of an intermediate drug load formulation was performed using horizontally and vertically force fed roll compactors. The horizontally fed roll compactor was equipped with an instrumented roll technology allowing the direct measurement of normal
Carmen C Denman et al.
Microbiology (Reading, England), 159(Pt 4), 771-781 (2013-02-05)
Burkholderia multivorans, a member of the Burkholderia cepacia complex (Bcc), is an important pathogen of the cystic fibrosis (CF) lung. Mannitol, approved as an inhaled osmolyte therapy for use in CF patients, promotes exopolysaccharide (EPS) production by the Bcc. In
Matthias Buntru et al.
Biotechnology and bioengineering, 112(5), 867-878 (2014-11-26)
Cell-free protein synthesis is a powerful method for the high-throughput production of recombinant proteins, especially proteins that are difficult to express in living cells. Here we describe a coupled cell-free transcription-translation system based on tobacco BY-2 cell lysates (BYLs). Using
Waseem Kaialy et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 68, 56-67 (2014-12-17)
The purpose of this work was to evaluate the physicochemical and inhalation characteristics of different size fractions of a promising carrier, i.e., freeze-dried mannitol (FDM). FDM was prepared and sieved into four size fractions. FDMs were then characterized in terms
Meizhong Luo et al.
Journal of AOAC International, 96(5), 1048-1053 (2013-11-29)
A discrimination method based on polyalcohol determination was developed for authenticity of protected geographical indication (PGI) vinegars-Shanxi extra aged vinegar (SVs) in China. Six polyalcohols in vinegars including erythritol, arabitol, xylitol, inositol, mannitol, and sorbitol were selected as the PGI
Itay Israel Shemesh et al.
PloS one, 9(12), e114287-e114287 (2014-12-05)
Diabetic nephropathy (DN) is characterized by proliferation of mesangial cells, mesangial expansion, hypertrophy and extracellular matrix accumulation. Previous data have cross-linked PKB (AKT) to TGFβ induced matrix modulation. The non-toxic compound AS101 has been previously shown to favorably affect renal
Young-Hoon Kim et al.
Nature communications, 6, 7451-7451 (2015-06-17)
Group O D-negative blood cells are universal donors in transfusion medicine and methods for converting other blood groups into this universal donor group have been researched. However, conversion of D-positive cells into D-negative is yet to be achieved, although conversion
Daniel J Wichelecki et al.
The Journal of biological chemistry, 290(48), 28963-28976 (2015-10-17)
Innovations in the discovery of the functions of uncharacterized proteins/enzymes have become increasingly important as advances in sequencing technology flood protein databases with an exponentially growing number of open reading frames. This study documents one such innovation developed by the
A J Esbaugh et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 188, 120-126 (2015-07-01)
Burmese pythons are sit-and-wait predators that are well adapted to go long periods without food, yet subsequently consume and digest single meals that can exceed their body weight. These large feeding events result in a dramatic alkaline tide that is
Hendrik Graefe et al.
Clinical chemistry and laboratory medicine, 41(8), 1049-1055 (2003-09-11)
Mannitol is an osmotically active polyalcohol often present in fluids used for irrigation of exposed tissue during minimal invasive surgery. Since this polyol normally is not detected in human plasma to any significant extent, it may be used as a
Qiu-Yun Zhu et al.
Journal of nanoscience and nanotechnology, 15(12), 9539-9547 (2015-12-19)
Nanostructured lipid carriers (NLC) are a promising pharmaceutical delivery system with mean diameter less than 200 nm which are dispersed in an aqueous phase containing emulsifier(s), to increase the water solubility, stability and bioavailability of oil compounds. Herein we prepared
N Hendoui et al.
European review for medical and pharmacological sciences, 17(4), 477-485 (2013-03-08)
Osmotherapy is a cornerstone for the management of severe Traumatic Brain Injury (TBI). Hypertonic saline (HTS) has advantages as being preferred osmotic agent, but there is inadequte knowledge regarding dose and its saftey in comparison to mannitol. S100B, as a
Shona A Mookerjee et al.
Biochimica et biophysica acta, 1847(2), 171-181 (2014-12-03)
The rate at which cells acidify the extracellular medium is frequently used to report glycolytic rate, with the implicit assumption that conversion of uncharged glucose or glycogen to lactate(-)+H(+) is the only significant source of acidification. However, another potential source
Martin Kuentz et al.
Drug development and industrial pharmacy, 39(9), 1476-1483 (2012-10-10)
An automated version of uniaxial powder flow testing has recently been developed and there is a need for experimental data from pharmaceutical powders. To compare the novel testing method with an annular shear cell using different pharmaceutical excipients. A particular
David A Katzka et al.
Gut, 64(4), 538-543 (2014-06-25)
Eosinophilic oesophagitis (EoE) is presumed to be an isolated oesophageal disease; yet other allergic diseases associated with eosinophilic infiltration of target tissues, such as asthma and eczema, show perturbed functions of other sites that may be involved in the diathesis
Katharine Hurt et al.
Expert review of respiratory medicine, 6(1), 19-26 (2012-01-31)
Inhaled dry powder mannitol is well established for use in bronchial provocation testing. Inhaled mannitol also increases mucociliary clearance, and therefore could have a role in treating chronic suppurative lung disease. There have been a number of studies in cystic
Roberto Pisano et al.
Journal of pharmaceutical sciences, 103(6), 1756-1765 (2014-04-24)
This paper deals with the problem of monitoring the freeze-drying process of thermo-labile products and particularly tracking the temperature and the position of the interface of sublimation. A novel and affordable way is proposed to estimate the vapor flow rate
Charles M A P Franz et al.
Medical microbiology and immunology, 204(4), 527-538 (2014-11-25)
The effect of a daily intake of the probiotic strain Lactobacillus casei Shirota (LcS) on the colonisation of pathogens, specifically streptococci and Staphylococcus aureus, in the nose and throat of healthy human volunteers with low natural killer cell activity, was
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