Search Within
m9140
Applied Filters:
Keyword:'m9140'
Showing 1-30 of 292 results for "m9140" within Papers
Shawn D MacKenzie et al.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 55(5), 571-581 (2014-03-14)
A minimally invasive method for delivering injectable therapeutic agents would be desirable for the treatment of intervertebral disc disease in dogs. The purpose of this study was to compare computed tomography (CT), ultrasonography (US), and fluoroscopy modalities for guiding percutaneous
Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes.
Tamirat Gebru et al.
Antimicrobial agents and chemotherapy, 58(12), 7398-7404 (2014-10-01)
Plasmodium falciparum gametocytes are not associated with clinical symptoms, but they are responsible for transmitting the pathogen to mosquitoes. Therefore, gametocytocidal interventions are important for malaria control and resistance containment. Currently available drugs and vaccines are not well suited for
Lin Zhang et al.
Journal of experimental & clinical cancer research : CR, 28, 78-78 (2009-06-12)
FBG2 (F-BOX6) gene is an important member in ubiquitin metabolic system F-BOX family, and forms E3 complex with the other members in the family. But its role in gastric cancer is still not clear. In the present study, we intended
John N McGinley et al.
Biological procedures online, 12(1), 9032-9032 (2010-01-01)
The use of architectural and morphological characteristics of cells for establishing prognostic indicators by which individual pathologies are assigned grade and stage is a well-accepted practice. Advances in automated micro- and macroscopic image acquisition and digital image analysis have created
Leonardo Guasti et al.
The Journal of clinical endocrinology and metabolism, 99(11), E2198-E2206 (2014-08-20)
The hormone fibroblast growth factor 21 (FGF21) is a key metabolic regulator in the adaptation to fasting. In food-restricted mice, inhibition of skeletal growth is mediated by the antagonistic effect of FGF21 on GH action in the liver and growth
Pilho Kim et al.
Journal of medicinal chemistry, 52(5), 1317-1328 (2009-02-13)
The 4-nitroimidazole PA-824 is active against aerobic and anaerobic Mycobacterium tuberculosis (Mtb) while 5-nitroimidazoles like metronidazole are active against only anaerobic Mtb. We have synthesized analogues of both 4- and 5-nitroimidazoles and explored their antitubercular activities. The nitro group is
Valentina Di Felice et al.
Journal of tissue engineering and regenerative medicine, 9(11), E51-E64 (2013-04-18)
The use of three-dimensional (3D) cultures may induce cardiac progenitor cells to synthesize their own extracellular matrix (ECM) and sarcomeric proteins to initiate cardiac differentiation. 3D cultures grown on synthetic scaffolds may favour the implantation and survival of stem cells
Yongfeng Li et al.
International journal of nanomedicine, 10, 4549-4563 (2015-07-28)
We developed a hierarchical hybrid micro/nanorough strontium-loaded Ti (MNT-Sr) surface fabricated through hydrofluoric acid etching followed by magnetron sputtering and evaluated the effects of this surface on osseointegration. Samples with a smooth Ti (ST) surface, micro Ti (MT) surface treated
Chunlei Tang et al.
Scientific reports, 5, 11241-11241 (2015-06-11)
Adenine nucleotide translocase (ANT) is a constitutive mitochondrial component that is involved in ADP/ATP exchange and mitochondrion-mediated apoptosis in yeast and mammals. However, little is known about the function of ANT in pathogenic fungi. In this study, we identified an
Anant Narayan Bhatt et al.
BMC cancer, 15, 335-335 (2015-05-01)
Cancer cells exhibit increased glycolysis for ATP production (the Warburg effect) and macromolecular biosynthesis; it is also linked with therapeutic resistance that is generally associated with compromised respiratory metabolism. Molecular mechanisms underlying radio-resistance linked to elevated glycolysis remain incompletely understood.
Mascha S Recks et al.
Clinical immunology (Orlando, Fla.), 159(1), 93-106 (2015-05-12)
Here we studied the autoantibody specificity elicited by proteolipid protein (PLP) in MP4-induced experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis (MS). In C57BL/6 (B6) mice, antibodies were induced by immunization with one of the two extracellular and by
Yolanda Corbett et al.
Microbes and infection, 17(3), 184-194 (2014-12-03)
In malaria, the evidence concerning the nucleotide-binding, oligomerization domain (NOD) 2 (NOD2) receptor is fragmented and the stimuli that might activate NOD2 are not well characterized. We investigated the role of NOD2 in vitro in the response of macrophages to Plasmodium
Tamer Al Kayal et al.
PloS one, 10(4), e0125110-e0125110 (2015-04-22)
Demineralized bone matrix (DBM) is widely used for bone regeneration. Since DBM is prepared in powder form its handling properties are not optimal and limit the clinical use of this material. Various synthetic and biological carriers have been used to
Vishwan Pamarthi et al.
Journal of vascular and interventional radiology : JVIR, 25(9), 1398-1404 (2014-05-20)
To review the indications, technical approach, and clinical outcomes of thoracic duct embolization (TDE) and thoracic duct disruption (TDD) in patients with symptomatic chylous effusions. A total of 105 patients who underwent 120 consecutive TDE/TDD procedures were retrospectively reviewed. Data
Tao Peng et al.
RNA biology, 13(10), 988-999 (2016-07-16)
Singlet oxygen is generated by bacteriochlorophylls when light and oxygen are simultaneously present in Rhodobacter sphaeroides. Singlet oxygen triggers a specific response that is partly regulated by the alternative sigma factor RpoHI/HII. The sRNA RSs2461 has previously been identified as
Iandra Holzmann et al.
Pharmacology, biochemistry, and behavior, 136, 55-63 (2015-07-22)
Olfactory bulbectomy (OB) is an animal model of depression that can mimic symptoms that are characteristic of depressive patients, such as behavioral, neurochemical and neuromorphological changes. Quercetin decreased the immobility time in the forced swimming test and tail suspension test.
Lennart Weber et al.
PloS one, 11(11), e0165694-e0165694 (2016-11-02)
Cell division and cell wall synthesis mechanisms are similarly conserved among bacteria. Consequently some bacterial species have comparable sets of genes organized in the dcw (division and cell wall) gene cluster. Dcw genes, their regulation and their relative order within
Rajasekhar N V S Suragani et al.
Blood, 123(25), 3864-3872 (2014-05-06)
In β-thalassemia, unequal production of α- and β-globin chains in erythroid precursors causes apoptosis and inhibition of late-stage erythroid differentiation, leading to anemia, ineffective erythropoiesis (IE), and dysregulated iron homeostasis. Here we used a murine model of β-thalassemia intermedia (Hbb(th1/th1)
Muna S Elburki et al.
Mediators of inflammation, 2014, 959471-959471 (2014-08-12)
Tetracycline-based matrix metalloproteinase- (MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic MMP-inhibitor not based on an antibiotic. To induce experimental periodontitis, endotoxin (LPS) was repeatedly
Letícia C Bonkovoski et al.
International journal of pharmaceutics, 477(1-2), 197-207 (2014-10-15)
For the first time, polyelectrolyte complex based on poly[(2-dimethylamino) ethyl methacrylate] (PDMAEMA) and chondroitin sulfate (CS) was prepared. The properties of novel material and precursors were investigated by WAXS, FTIR, TGA, SEM and DLS analysis. The PDMAEMA/CS PECs presented hydrophilic-hydrophobic
Fiona C Shenton et al.
Journal of anatomy, 238(1), 36-52 (2020-08-13)
Cardiac reflexes originating from sensory receptors in the heart ensure blood supply to vital tissues and organs in the face of constantly changing demands. Atrial volume receptors are mechanically sensitive vagal afferents which relay to the medulla and hypothalamus, affecting
M A Babcook et al.
Cell death & disease, 5, e1536-e1536 (2014-11-21)
Castration-resistant prostate cancer (CRPC) cells acquire resistance to chemotherapy and apoptosis, in part, due to enhanced aerobic glycolysis and biomass production, known as the Warburg effect. We previously demonstrated that combination simvastatin (SIM) and metformin (MET) ameliorates critical Warburg effect-related
Mindy R Rabinowitz et al.
The Laryngoscope, 124(11), 2531-2536 (2014-06-14)
Sentinel lymph node biopsy (SLNB) has been utilized for cutaneous melanoma and other malignancies arising from the eye and ocular adnexa. Currently, SLNB requires blue dyes and/or radiopharmaceuticals; both of which have significant shortcomings. This study sought to evaluate the
Fazal Adnan et al.
RNA biology, 12(5), 569-577 (2015-04-03)
Exposure to oxygen and light generates photooxidative stress by the bacteriochlorophyll a mediated formation of singlet oxygen ((1)O2) in the facultative photosynthetic bacterium Rhodobacter sphaeroides. We have identified SorY as an sRNA, which is induced under several stress conditions and
Margarida Nunes et al.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 21(1), 63-77 (2015-03-20)
This work comprises the use of a multi-analytical approach combined with microbiological studies to characterize six paper samples, containing foxing stains, from the 20th century, regarding their cellulose matrix, fillers, and sizing materials, and to evaluate possible paper degradation that
Jemina Lehto et al.
Cancers, 13(6) (2021-04-04)
The C-X3-C motif chemokine receptor 1 (CX3CR1, fractalkine receptor) is associated with neoplastic transformation, inflammation, neurodegenerative diseases and aging, and the small molecule inhibitor KAND567 targeting CX3CR1 (CX3CR1i) is evaluated in clinical trials for acute systemic inflammation upon SARS-CoV-2 infections.
Alison A Staton et al.
Nature protocols, 6(12), 2035-2049 (2011-12-03)
MicroRNAs (miRNAs) regulate gene expression by pairing with complementary sequences in the 3' untranslated regions (UTRs) of transcripts. Although the molecular mechanism underlying miRNA biogenesis and activity is becoming better understood, determining the physiological role of the interaction of an
Gopal Kushawah et al.
Developmental cell, 54(6), 805-817 (2020-08-10)
Early embryonic development is driven exclusively by maternal gene products deposited into the oocyte. Although critical in establishing early developmental programs, maternal gene functions have remained elusive due to a paucity of techniques for their systematic disruption and assessment. CRISPR-Cas13
Valerio Matozzo et al.
Fish & shellfish immunology, 45(2), 528-533 (2015-05-20)
The cuttlefish Sepia officinalis is an important fishery resource in the Northern Adriatic Sea (Italy). During reproduction, fertilised eggs are released by adult females in coastal waters and embryo development can take over two months. During this period, embryos rely
Claus Hedegaard et al.
FEBS open bio, 3, 411-420 (2013-11-20)
Synapsin 1 (SYN1) is a phosphoprotein involved in nerve signal transmission. The porcine SYN1 promoter orthologue was cloned and characterized to provide a means of expressing a transgene specifically in neurons. The nucleotide sequence of the promoter displayed a high
Page 1 of 10