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Showing 1-30 of 612 results for "N6639" within Papers
Ci-Hai Zhang et al.
International journal of biological macromolecules, 79, 681-686 (2015-06-09)
Glycyrrhiza uralensis, an important Chinese medicine, has a long history of use in China. In this study, three water-soluble polysaccharides fractions (GUPs-1, GUPs-2 and GUPs-3) were isolated and purified from the root of G. uralensis by DEAE-52 and Sephadex G-100
Andreas von Bohl et al.
Malaria journal, 14, 435-435 (2015-11-06)
During development in human erythrocytes, Plasmodium falciparum parasites display a remarkable number of adhesive proteins on their plasma membrane. In the invasive merozoites, these include members of the PfMSP1 and PfAMA1/RON complexes, which facilitate contact between merozoites and red blood
Chia-Ying Lien et al.
Journal of physiology and biochemistry, 71(4), 669-678 (2015-09-26)
Doxorubicin (DOX) is a potent and widely used antineoplastic agent. Despite the efficacy of DOX, its clinical use is limited by a dose-dependent cardiotoxicity. Chronic exercise training has been shown to protect against DOX-induced cardiotoxicity. It is less clear whether
Hippocampal neuronal maturation triggers post-synaptic clustering of brain temperature-sensor TRPV4.
Koji Shibasaki et al.
Biochemical and biophysical research communications, 458(1), 168-173 (2015-02-01)
Compartmentalization of neuronal function is achieved via specifically localized clustering of ion channels in discrete subcellular membrane domains. Transient receptor potential (TRP) channels exhibit highly variable cellular and subcellular patterns of expression. We previously revealed that the thermo-sensor TRPV4 (activated
Hongping Chen et al.
Neuroreport, 26(14), 870-876 (2015-08-25)
Leptin is widely distributed in many tissues, including the nervous system. However, the ontogeny of leptin expression in the dorsal root ganglion (DRG) is unclear. Recent studies have shown that leptin is involved in the regulation of neuropathic pain induced
Ting Liu et al.
Oncotarget, 6(10), 7992-8006 (2015-03-24)
All-trans retinoic acid (ATRA) is a differentiating agent for the treatment of acute promyelocytic leukemia (APL). However, the therapeutic efficacy of ATRA has limitations. Tetrandrine is a traditional Chinese medicinal herb extract with antitumor effects. In this study, we investigated
Freda E-C Jen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 3828-3838 (2015-06-03)
Under conditions of low oxygen availability, Neisseria meningitidis and Neisseria gonorrhoeae are able to respire via a partial denitrification pathway in which nitrite is converted to nitrous oxide. In this process, nitrite reductase (AniA), a copper (Cu)-containing protein converts nitrite
Yujie Chang et al.
PloS one, 10(11), e0142952-e0142952 (2015-11-19)
Lysine is the most limiting essential amino acid for animal nutrition in maize grains. Expression of naturally lysine-rich protein genes can increase the lysine and protein contents in maize seeds. AtMAP18 from Arabidopsis thaliana encoding a microtubule-associated protein with high-lysine
Su-Mi Woo et al.
Molecules and cells, 38(7), 604-609 (2015-06-13)
The active metabolite of vitamin D such as 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) is a well-known key regulatory factor in bone metabolism. However, little is known about the potential of vitamin D as an odontogenic inducer in human dental pulp cells (HDPCs)
Birgit Hegner Satir et al.
Cell biology international, 39(2), 136-145 (2014-07-22)
Parafusin (PFUS), a 63 kDa protein first discovered in the eukaryote Paramecium and known for its role in apicomplexan exocytosis, provides a model for the common origin of cellular systems employing scaffold proteins for targeting and signaling. PFUS is closely related
Yanfen Ma et al.
Microbes and infection, 17(6), 440-450 (2015-04-23)
Chagas disease caused by Trypanosoma cruzi is a major neglected tropical parasitic disease. The pathogenesis of this infection remains disputable. There is no suitable vaccine for the prevention. Attenuated live vaccines can provide strong protection against infection; however, there are
Saida Haider et al.
Life sciences, 124, 110-119 (2015-02-01)
D-Galactose (D-gal) induced accelerated senescence has been used to develop an aging model for brain. Previously, long term administration of a wide range of doses has been used for this purpose. In the present study we investigate whether short term
Merve Erdem et al.
Pediatric hematology and oncology, 32(3), 182-192 (2014-09-24)
Human ether-a-go-go related gene (herg) encoding HERG K(+) channel has been demonstrated in many previous studies with its association to cell cycle progression and growth in tumor cells. The upregulated expression of HERG K+ channels was determined in different tumor
Swati Rawat et al.
Journal of molecular biology, 427(5), 1023-1037 (2014-05-23)
The transmembrane (TM) helices of most type II single-span membrane proteins (S-SMPs) of Escherichia coli occur near the N-terminus, where the cell's targeting mechanisms can readily identify it as it emerges from the ribosome. However, the TM helices of a
Pui San Wong et al.
Pharmacological research, 91, 29-35 (2014-12-03)
Oxygenation with 95%O2 is routinely used in organ bath studies. However, hyperoxia may affect tissue responses, particularly in studies which involve reactive oxygen species (ROS). Here, the effects of the antioxidant, Tiron, were investigated under different gassing conditions in the
Shaotong Zhu et al.
The Journal of biological chemistry, 290(34), 20761-20773 (2015-07-03)
Complex I (NADH:ubiquinone oxidoreductase) is a multisubunit, membrane-bound enzyme of the respiratory chain. The energy from NADH oxidation in the peripheral region of the enzyme is used to drive proton translocation across the membrane. One of the integral membrane subunits
Kuttikkadan A Rony et al.
International journal of medicinal mushrooms, 17(6), 521-531 (2015-09-10)
Phellinus rimosus is a parasitic host specific polypore mushroom with profound antioxidant, antihepatotoxic, anti-inflammatory, antitumor, and antimutagenic activities. This study investigated the hypoglycemic and hypolipidemic activities of the wood-inhabiting polypore mushroom Ph. Rimosus in streptozotocin (STZ)-induced diabetic rats. Diabetes was
Bradley O Elmore et al.
PloS one, 10(5), e0125027-e0125027 (2015-05-06)
Serum lipoproteins (LP) are increasingly being recognized as dual purpose molecules that contribute to both cholesterol homeostasis and host innate defense. In fact, very low LP levels are associated with increased risk of bacterial infection in critically ill patients. In
Christine Y Y Wai et al.
PloS one, 9(11), e111649-e111649 (2014-11-05)
Designer proteins deprived of its IgE-binding reactivity are being sought as a regimen for allergen-specific immunotherapy. Although shrimp tropomyosin (Met e 1) has long been identified as the major shellfish allergen, no immunotherapy is currently available. In this study, we
Fraser L Collins et al.
Journal of immunology research, 2015, 901679-901679 (2015-06-13)
Objectives. Genome wide association studies identified TNFSF member TNF-like protein 1A (TL1A, TNFSF15) as a potential modulator of ankylosing spondylitis (AS). TL1A is the only confirmed TNFSF ligand of death receptor 3 (DR3, TNFRSF25); however, its role in disease pathology
Supriya Upadhyay et al.
PloS one, 10(9), e0138056-e0138056 (2015-09-12)
The study investigated the presence of CTX-M-15 type extended spectrum beta-lactamases (ESBL), compared their genetic arrangements and plasmid types in gram negative isolates of hospital and food origin in north-east India. From September 2013 to April 2014, a total of
Jesica Raineri et al.
Plant cell reports, 34(12), 2065-2080 (2015-08-08)
Arabidopsis transgenic plants expressing the sunflower transcription factor HaWRKY76 exhibit increased yield and tolerance to drought and flood stresses. The genetic construct containing HaWRKY76 is proposed as a potential biotechnological tool to improve crops. Water deficit and water excess are
Sook Hyun Chung et al.
PloS one, 10(3), e0118949-e0118949 (2015-03-06)
Dysfunction of Müller cells has been implicated in the pathogenesis of several retinal diseases. In order to understand the potential contribution of Müller cells to retinal disease better, we have developed a transgenic model in which foci of Müller cell
Yisheng Yang et al.
Gene expression patterns : GEP, 19(1-2), 45-51 (2015-07-30)
Lhx9 is a member of the LIM-homeodomain gene family necessary for the correct development of many organs including gonads, limbs, heart and the nervous system. In the context of limb development, Lhx9 has been implicated as an integrator for Fibroblast
Yingbin Shen et al.
Food chemistry, 194, 1003-1012 (2015-10-17)
The objective of this study was to determine the antioxidant capacity of polyphenols extracted from black highland barley (BHLPE) in vitro and in vivo. BHLPE was found to have strong superoxide radical, hydroxyl radical and 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, ferric reducing
Seiji Shibasaki et al.
AMB Express, 4(1), 82-82 (2015-08-13)
Affibody molecules specific for H-Ras and Raf-1 were evaluated for their ability to inhibit synovial cell function. Affibody molecules targeting H-Ras (Zras122, Zras220, and Zras521) or Raf-1 (Zraf322) were introduced into the MH7A synovial cell line using two delivery methods:
Su-Chen Ho et al.
Molecules (Basel, Switzerland), 19(11), 17697-17714 (2014-11-05)
The anti-neuroinflammatory capacities of raw and steamed garlic extracts as well as five organosulfur compounds (OSCs) were examined in lipopolysaccharide (LPS)-stimulated BV2 microglia. According to those results, steaming pretreatment blocked the formation of alliinase-catalyzed OSCs such as allicin and diallyl
Guijin Sun et al.
Molecules (Basel, Switzerland), 20(10), 18539-18550 (2015-10-17)
In this study, we cloned the full-length cDNA of E-selectin of zebrafish (Danio rerio), analyzed its expression pattern and preliminarily explored its biological function. Zebrafish E-selectin cDNA is 3146 bp and encodes a putative 871 amino acid protein. All structural
Soham Mitra et al.
Scientific reports, 5, 13949-13949 (2015-09-15)
The MPTP mediated neurodegeneration in substantia nigra has been well studied, but not the status of frontal cortex. The novelty of the present study is to explore the sex difference of frontal cortex during MPTP intoxication and to investigate the
Joanna Simińska et al.
Plant physiology and biochemistry : PPB, 96, 209-216 (2015-08-25)
Storage proteins of cereal seeds are processed during accumulation and degraded during germination primarily by cysteine proteinases. One of the mechanisms controlling the activity of these enzymes is the synthesis of specific inhibitors named phytocystatins. Here we present the complete
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