na1111

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Showing 1-30 of 47 results for "na1111" within Papers

Comparison of antibacterial effectiveness of three rotary file system with different geometry in infected root canals before and after instrumentation-a double-blinded randomized controlled clinical trial.

Riluwan Siddique et al.

BDJ open, 6, 8-8 (2020-06-19)

To compare the antibacterial effectiveness of three rotary file systems i.e., ProTaper Next, ProTaper Gold and XP-endo Shaper in root canals of teeth with asymptomatic apical periodontitis by using the real-time polymerase chain reaction. Root canals from single or multi-rooted

Mutation analysis of the SLC4A11 gene in Indian families with congenital hereditary endothelial dystrophy 2 and a review of the literature.

Srinivas Gopinath Kodaganur et al.

Molecular vision, 19, 1694-1706 (2013-08-08)

Congenital hereditary endothelial dystrophy 2 (CHED2) is an autosomal recessive disorder caused by mutations in the solute carrier family 4, sodium borate transporter, member 11 (SLC4A11) gene. The purpose of this study was to identify the genetic cause of CHED2

The relaxase of the Rhizobium etli symbiotic plasmid shows nic site cis-acting preference.

Daniel Pérez-Mendoza et al.

Journal of bacteriology, 188(21), 7488-7499 (2006-08-19)

Genetic and biochemical characterization of TraA, the relaxase of symbiotic plasmid pRetCFN42d from Rhizobium etli, is described. After purifying the relaxase domain (N265TraA), we demonstrated nic binding and cleavage activity in vitro and thus characterized for the first time the

Characterizing novel olfactory receptors expressed in the murine renal cortex.

Victoria L Halperin Kuhns et al.

American journal of physiology. Renal physiology, 317(1), F172-F186 (2019-05-02)

The kidney uses specialized G protein-coupled receptors, including olfactory receptors (ORs), to act as sensors of molecules and metabolites. In the present study, we cloned and studied seven renal ORs, which we previously found to be expressed in the murine

Methylated Vnn1 at promoter regions induces asthma occurrence via the PI3K/Akt/NFκB-mediated inflammation in IUGR mice.

Yan Xing et al.

Biology open, 9(4) (2020-03-07)

Infants with intrauterine growth retardation (IUGR) have a high risk of developing bronchial asthma in childhood, but the underlying mechanisms remain unclear. This study aimed to disclose the role of vascular non-inflammatory molecule 1 (vannin-1, encoded by the Vnn1 gene)

Analysis of ARID2 Gene Mutation in Oral Squamous Cell Carcinoma

Lakshmi Prabha Das et al.

Asian Pacific journal of cancer prevention : APJCP, 18(10), 2679-2681 (2017-10-27)

Background: The ARID2 gene, encoding a sub unit of the chromatin remodelling complex, has a possible tumour suppressor function and has been found to be frequently mutated in various tumours, including gingivo buccal oral squamous cell carcinomas. The present study

Coordinated transcriptional regulation of two key genes in the lignin branch pathway--CAD and CCR--is mediated through MYB- binding sites.

Anjanirina Rahantamalala et al.

BMC plant biology, 10, 130-130 (2010-06-30)

Cinnamoyl CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) catalyze the final steps in the biosynthesis of monolignols, the monomeric units of the phenolic lignin polymers which confer rigidity, imperviousness and resistance to biodegradation to cell walls. We have previously

ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.

Diana Guallar et al.

Cell stem cell, 27(2), 300-314 (2020-05-13)

RNA editing of adenosine to inosine (A to I) is catalyzed by ADAR1 and dramatically alters the cellular transcriptome, although its functional roles in somatic cell reprogramming are largely unexplored. Here, we show that loss of ADAR1-mediated A-to-I editing disrupts

Identification of a novel heterozygous truncation mutation in exon 1 of ARHGAP29 in an Indian subject with nonsyndromic cleft lip with cleft palate.

Deepak Chandrasekharan et al.

European journal of dentistry, 8(4), 528-532 (2014-12-17)

Mutations in exon 1 of ARHGAP29, a RhoA specific GTPase have been identified in North American and Filipino subjects with nonsyndromic cleft palate and cleft lip with or without cleft palate. Since the genetic status of ARHGAP29 in Indian subjects

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.

Célia Deville et al.

Cell reports, 27(12), 3433-3446 (2019-06-20)

AAA+ proteins form asymmetric hexameric rings that hydrolyze ATP and thread substrate proteins through a central channel via mobile substrate-binding pore loops. Understanding how ATPase and threading activities are regulated and intertwined is key to understanding the AAA+ protein mechanism.

Expression of Insulin-Like Growth Factor 1 (IGF-1) and Epidermal Growth Factor (EGF) Receptors and the Effect of IGF-1 and EGF on Androgen and Estrogen Release in the Myometrium of Pigs-In Vitro Study.

Ewa Monika Waszkiewicz et al.

Animals : an open access journal from MDPI, 10(5) (2020-05-30)

Porcine myometrium possesses steroidogenic activity but its regulation is not well understood. It was hypothesized that the regulators of myometrial steroidogenesis are insulin-like growth factor 1 (IGF-1) and epidermal growth factor (EGF), which were found to modulate the steroidogenic activity

Effects of IL-10- and FasL-overexpressing dendritic cells on liver transplantation tolerance in a heterotopic liver transplantation rat model.

Lihong Chen et al.

Immunology and cell biology, 97(8), 714-725 (2019-04-13)

Acute rejection is the major determinant for the long-term survival of donor liver after liver transplantation (LT). The aim of this study was to examine the therapeutic potential of interleukin (IL)-10-FasL-overexpressing immature dendritic cells (imDCs) to induce local immunosuppression in

GAPDH Pseudogenes and the Quantification of Feline Genomic DNA Equivalents.

A Katrin Helfer-Hungerbuehler et al.

Molecular biology international, 2013, 587680-587680 (2013-06-06)

Quantitative real-time PCR (qPCR) is broadly used to detect and quantify nucleic acid targets. In order to determine cell copy number and genome equivalents, a suitable reference gene that is present in a defined number in the genome is needed

Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.

Sara N Mitchell et al.

PloS one, 9(3), e92662-e92662 (2014-03-29)

The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both

Expression profile of salivary micro RNA-21 and 31 in oral potentially malignant disorders.

Thirupambaram Natarajasundaram Uma Maheswari et al.

Brazilian oral research, 34, e002-e002 (2020-02-13)

Oral potentially malignant disorders (OPMD) possess significant chances of malignancy conversion. In order to develop an early diagnostic tool, the present study evaluated the expression of miRNA-21 and 31 as salivary markers. The case-control study was carried out in 36

A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia.

Bob Glaudemans et al.

The Journal of clinical investigation, 119(4), 936-942 (2009-03-25)

Primary hypomagnesemia is a heterogeneous group of disorders characterized by renal or intestinal magnesium (Mg2+) wasting, resulting in tetany, cardiac arrhythmias, and seizures. The kidney plays an essential role in maintaining blood Mg2+ levels, with a prominent function for the

Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer.

Santosh Gupta et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 23(5), 1346-1357 (2016-09-08)

Purpose: Beyond enumeration, circulating tumor cells (CTCs) can provide genetic information from metastatic cancer that may facilitate a greater understanding of tumor biology and enable a precision medicine approach.Experimental Design: CTCs and paired leukocytes from men with metastatic castration-resistant prostate

A novel heterozygous mutation (F252Y) in exon 7 of the IRF6 gene is associated with oral squamous cell carcinomas.

Anil Melath et al.

Asian Pacific journal of cancer prevention : APJCP, 14(11), 6803-6806 (2014-01-01)

Interferon regulatory factor 6 (IRF6) is a transcription factor with distinct and conserved DNA and protein binding domains. Mutations within the protein binding domain have been significantly observed in subjects with orofacial cleft relative to healthy controls. In addition, recent

Heterozygous Ile453Val codon mutation in exon 7, homozygous single nucleotide polymorphisms in intron 2 and 5 of cathepsin C are associated with Haim-Munk syndrome.

Aswath N

European journal of dentistry, 8(1), 79-84 (2014)

Boron Uptake Assay in Xenopus laevis Oocytes.

Sheliang Wang et al.

Bio-protocol, 8(5), e2755-e2755 (2018-03-05)

Boron (B) is essential for plant growth and taken up by plant roots as boric acid. Under B limitation, B uptake and translocation in plants are dependent on the boric acid channels located in the plasma membrane. Xenopus leavis oocyte

Common docking domain mutation E322K of the ERK2 gene is infrequent in oral squamous cell carcinomas.

Gopalakrishnan Mohan Valiathan et al.

Asian Pacific journal of cancer prevention : APJCP, 13(12), 6155-6157 (2012-01-01)

Mutations in the MAPK (Mitogen Activated Protein Kinase) signaling pathway - EGFR/Ras/ RAF/MEK have been associated with the development of several carcinomas. ERK2, a downstream target of the MAPK pathway and a founding member of the MAPK family is activated

Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA.

Vernon K Ward et al.

Proceedings of the National Academy of Sciences of the United States of America, 104(26), 11050-11055 (2007-06-22)

Noroviruses are the major cause of nonbacterial gastroenteritis in humans. These viruses have remained refractory to detailed molecular studies because of the lack of a reverse genetics system coupled to a permissive cell line for targeted genetic manipulation. There is

CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

Constant V Edi et al.

PLoS genetics, 10(3), e1004236-e1004236 (2014-03-22)

Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative insecticides is advocated for indoor residual spraying (IRS), and carbamates are increasingly important. Emergence of a very strong

The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation.

Puja Yadav et al.

Nucleic acids research, 44(2), 718-729 (2015-11-04)

Highly transcribed guanine-run containing sequences, in Saccharomyces cerevisiae, become unstable when topoisomerase I (Top1) is disrupted. Topological changes, such as the formation of extended RNA:DNA hybrids or R-loops or non-canonical DNA structures including G-quadruplexes has been proposed as the major

Exposure of phototrophs to 548 days in low Earth orbit: microbial selection pressures in outer space and on early earth.

Charles S Cockell et al.

The ISME journal, 5(10), 1671-1682 (2011-05-20)

An epilithic microbial community was launched into low Earth orbit, and exposed to conditions in outer space for 548 days on the European Space Agency EXPOSE-E facility outside the International Space Station. The natural phototroph biofilm was augmented with akinetes

The Gastric Ganglion of Octopus vulgaris: Preliminary Characterization of Gene- and Putative Neurochemical-Complexity, and the Effect of Aggregata octopiana Digestive Tract Infection on Gene Expression.

Elena Baldascino et al.

Frontiers in physiology, 8, 1001-1001 (2018-01-13)

The gastric ganglion is the largest visceral ganglion in cephalopods. It is connected to the brain and is implicated in regulation of digestive tract functions. Here we have investigated the neurochemical complexity (through in silico gene expression analysis and immunohistochemistry)

Identification of a target gene and activating stimulus for the YpdA/YpdB histidine kinase/response regulator system in Escherichia coli.

Luitpold Fried et al.

Journal of bacteriology, 195(4), 807-815 (2012-12-12)

Escherichia coli contains 30 two-component systems (TCSs), each consisting of a histidine kinase and a response regulator. Whereas most TCSs are well characterized in this model organism, little is known about the YpdA/YpdB system. To identify YpdB-regulated genes, we compared

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.

Nora McFadden et al.

PLoS pathogens, 7(12), e1002413-e1002413 (2011-12-17)

Small RNA viruses have evolved many mechanisms to increase the capacity of their short genomes. Here we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus (MNV) subgenomic RNA, in an alternative

The discovery of antioxidants in marine microorganisms and their protective effects on the hepatic cells from chemical-induced oxidative stress.

Vikash Chandra Tripathi et al.

Free radical research, 54(2-3), 150-161 (2020-02-06)

The marine environment is emerging as a biodiversity resource for the discovery of natural molecules or chemical scaffolds with pharmaceutical activity. Marine microbes have a tremendous ability to sense and respond to their surroundings to survive in a stressful environment

Comprehensive mutation analysis of PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 genes is suggestive of a non- neoplastic nature of phenytoin induced gingival overgrowth.

Bhuminathan Swamikannu et al.

Asian Pacific journal of cancer prevention : APJCP, 14(5), 2743-2746 (2013-06-28)

Dilantin sodium (phenytoin) is an antiepileptic drug, which is routinely used to control generalized tonic clonic seizure and partial seizure episodes. A few case reports of oral squamous cell carcinomas arising from regions of phenytoin induced gingival overgrowth (GO), and

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