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Showing 1-30 of 65 results for "P3292" within Papers
Xiao-Qiang Zou et al.
Journal of agricultural and food chemistry, 60(37), 9415-9423 (2012-08-28)
Human milk fat substitutes (HMFSs) were prepared by a two-step process, namely, Lipozyme RM IM-catalyzed acidolysis of interesterified high-melting palm stearin with fatty acids from rapeseed oil and blending of the enzymatic product with the selected oils on the basis
Kimmo Halt et al.
Methods in molecular biology (Clifton, N.J.), 886, 23-30 (2012-05-29)
The organ culture setup of embryonic kidney has served as a model of nephrogenesis for several decades. In vitro culture of the mouse metanephric mesenchyme enables easy manipulation and analysis of the tissue and provides information of cellular interactions, morphogenesis
Mireille Andriamihaja et al.
Amino acids, 44(2), 563-572 (2012-09-12)
Utilisation of microbial enzymes may represent an alternative strategy to the use of conventional pancreatin obtained from pig pancreas for the treatment of severe pancreatic insufficiency. In this study, we focused on the capacity of two microbial preparations for their
C Giromini et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(8), 1436-1445 (2017-04-12)
Ex-food or former food products (FFPs) have been proposed as one of the categories with great promise as alternative feed ingredients. FFPs' nutritional potential is not yet fully exploited. Therefore, the aim of this study was to perform a nutritional
Shunwen Hu et al.
International journal of pharmaceutics, 441(1-2), 693-700 (2012-10-24)
The objective of this study was to investigate the integrtity and stability of oral liposomes containing glycocholate (SGC-Lip) in simulated gastrointestinal (GI) media and ex vivo GI media from rats in comparison with conventional liposomes (CH-Lip) composed of soybean phosphatidylcholine
Johanita Kruger et al.
Food & function, 11(5), 4138-4145 (2020-04-30)
Whole fruit and vegetable consumption is universally promoted as healthy, to a large extent due to their high contents of phytochemicals, including phenolics and dietary fibre. The major fibre in fruits and vegetables, pectin, however also decreases the bioavailability of
Randall E Burton et al.
The Journal of biological chemistry, 295(34), 12317-12327 (2020-07-16)
Bovine colostral antibodies, purified from cow's milk produced immediately after calving, have enhanced resistance to degradation by intestinal proteases relative to antibodies from human or bovine serum, making them of particular interest as orally administered therapeutic agents. However, the basis
Alessandra Amoroso et al.
Food chemistry, 140(4), 654-659 (2013-05-23)
α-Dicarbonyl compounds (α-DCs), such as glyoxal, methylglyoxal and 2,3-butanedione, are highly reactive substances occurring in thermally treated and fermented foods, that may react with amino and sulphydryl groups of side chains of proteins to form Maillard reaction end products, inducing
L V Vinokurova et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (7)(7), 59-63 (2012-03-01)
In order to identify features of the course pancreatic diabetes and discussion of the principles of conservative therapy were examined 66 patients with CP in age of 30 to 65 years (55 men, 11 women). Among them in 22 cases
Jin-Feng Yao et al.
Amino acids, 43(4), 1557-1566 (2012-02-14)
Long-acting luteinizing hormone-releasing hormone (LHRH) antagonists designed to be protease resistant consisted of a series of novel decapeptides structurally similar to LHRH. The aim of this study was to evaluate the in vitro metabolic stability of the LHRH decapeptides using
Sun-Jong You et al.
Journal of food science, 76(6), C801-C807 (2012-03-16)
Egg is a well-known rich source of bioactive peptides. In this study, egg protein (egg white and egg yolk proteins) hydrolysates were produced with gastrointestinal enzymes (pepsin and pancreatin) or nongastrointestinal enzymes (thermolysin and alcalase), and fractionated by ultrafiltration and
Frederique Ruf-Zamojski et al.
Nature communications, 12(1), 2677-2677 (2021-05-13)
To provide a multi-omics resource and investigate transcriptional regulatory mechanisms, we profile the transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from adult mouse pituitaries. Paired snRNAseq and snATACseq datasets from individual animals highlight a continuum between
C M Seiler et al.
Alimentary pharmacology & therapeutics, 37(7), 691-702 (2013-02-07)
Pancreatic exocrine insufficiency (PEI) often occurs following pancreatic surgery. To demonstrate the superior efficacy of pancreatin 25 000 minimicrospheres (Creon 25000 MMS; 9-15 capsules/day) over placebo in treating PEI after pancreatic resection. A 1-week, double-blind, randomised, placebo-controlled, parallel-group, multicentre study with
Zacharias Papanikolaou et al.
Journal of food science, 77(5), M298-M306 (2012-11-21)
Isolates (47) of lactobacilli from 5 different productions of Melichloro cheese were examined for potential use as adjunct cultures. The sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of whole-cell proteins classified 29 isolates as L. paraplantarum and 18 as L. paracasei
Gema Pereira-Caro et al.
International journal of food sciences and nutrition, 63(6), 703-707 (2012-01-25)
The digestive stability of two natural antioxidant compounds present in virgin olive oil, hydroxytyrosol (HTy) and hydroxytyrosyl acetate (HTy-Ac) and a new series of hydroxytyrosyl ethers (methyl, ethyl and butyl hydroxytyrosyl ethers) was evaluated by a simulated digestion procedure. High
Matthias Imboden et al.
Nature communications, 10(1), 834-834 (2019-02-21)
Systematic investigations of the effects of mechano-electric coupling (MEC) on cellular cardiac electrophysiology lack experimental systems suitable to subject tissues to in-vivo like strain patterns while simultaneously reporting changes in electrical activation. Here, we describe a self-contained motor-less device (mechano-active
Johanita Kruger et al.
Journal of agricultural and food chemistry, 67(20), 5792-5800 (2019-05-07)
Green leafy vegetables have low β-carotene bioavailability, which we hypothesized to be, at least in part, due to high contents of fiber, minerals, and phenolics. We investigated the effects of pectin (40-120 μg/mL), iron (50-150 μg/mL), ferulic acid (30-90 μg/mL)
Shoichi Miyamoto et al.
PloS one, 10(11), e0142904-e0142904 (2015-11-13)
Recently, it has been reported that specific microRNA (miRNA) levels are elevated in serum and can be used as biomarkers in patients with cardiovascular diseases. However, miRNAs expression profiles and their sources in pericardial fluid (PF) are unclear. The purpose
Chia-Rui Shen et al.
Molecules (Basel, Switzerland), 18(3), 2978-2987 (2013-03-06)
The versatile oligosaccharide biopolymers, chitin and chitosan, are typically produced using enzymatic processes. However, these processes are usually costly because chitinases and chitosanases are available in limited quantities. Fortunately, a number of commercial enzymes can hydrolyze chitin and chitosan to
Hyun Jung Kim et al.
Journal of agricultural and food chemistry, 60(20), 5237-5242 (2012-05-09)
The in vitro starch digestion rate and estimated glycemic index (GI) of oat flours and oat starches from typical and high β-glucan oat lines were evaluated along with the impact of heating on starch digestion. Flour from oat lines ('Jim'
Protocol: Adeno-Associated Virus-Mediated Gene Transfer in Ex Vivo Cultured Embryonic Mammary Gland.
Qiang Lan et al.
Journal of mammary gland biology and neoplasia, 25(4), 409-416 (2020-10-04)
Branching morphogenesis of the murine mammary gland starts during late embryogenesis. It is regulated by the signals emanating both from the epithelium and the mesenchyme, yet the molecular mechanisms regulating this process remain poorly understood. We have previously developed a
Hyunji Byun et al.
Reproductive biology and endocrinology : RB&E, 19(1), 112-112 (2021-07-18)
The tumor susceptibility gene 101 (Tsg101), a component of the endosomal sorting complex required for transport (ESCRT) complex I, is involved in multiple biological processes involving endomembranous structures and the plasma membrane. The role of Tsg101 in the uterine epithelium
Alberto Burgos-Edwards et al.
Food chemistry, 237, 1073-1082 (2017-08-03)
The wild Chilean currants Ribes magellanicum and R. punctatum are a good source of polyphenolic compounds. The effect of simulated gastrointestinal digestion (GID) on phenolic content, composition and antioxidant capacity was determined. The inhibitory activity of the non-digested and digested
Lotta Pohjolainen et al.
Frontiers in pharmacology, 11, 553852-553852 (2021-02-16)
Background: Hypertrophy of cardiomyocytes (CMs) is initially a compensatory mechanism to cardiac overload, but when prolonged, it leads to maladaptive myocardial remodeling, impairing cardiac function and causing heart failure. A key signaling molecule involved in cardiac hypertrophy is protein kinase
Xu-Dong Kong et al.
Nature biomedical engineering, 4(5), 560-571 (2020-05-13)
The oral administration of peptide drugs is hampered by their metabolic instability and limited intestinal uptake. Here, we describe a method for the generation of small target-specific peptides (less than 1,600 Da in size) that resist gastrointestinal proteases. By using
Johanna Hirvonen et al.
Journal of agricultural and food chemistry, 67(41), 11396-11402 (2019-09-21)
Phytase is commonly used as a feed enzyme in monogastric animals to increase the bioavailability of phytate phosphorus and other nutrients. The accumulation of myo-inositol phosphate intermediates during phytate degradation in various segments of the gastrointestinal tract (GIT) is poorly
Miriam Mahler et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(35), 11046-11062 (2012-07-26)
An efficient synthesis of (S)- or (R)-3-(benzyloxy-methyl)-cyclopent-3-enol was developed by appling an enzyme-catalyzed kinetic-resolution approach. This procedure allowed the syntheses of the enantiomeric building blocks (S)- and (R)-cyclopentenol with high optical purity (>98 % ee). In contrast to previous approaches
Jaroslaw Czubinski et al.
Food chemistry, 143, 418-426 (2013-09-24)
This study describes in vitro digestion of lupin seed globulins by pancreatin, trypsin and chymotrypsin. Lupin seed globulins turned out to be almost totally susceptible to chymotrypsin digestion. When panceratin or trypsin were used for digestion of lupin seed globulins
K E Aarak et al.
The British journal of nutrition, 110(8), 1402-1410 (2013-03-21)
In the present study, we hypothesised whether in vitro digestion of salmon oil would release different amounts of PUFA depending on the origin of the lipolytic enzymes used. For this purpose, in vitro digestion of salmon oil (SO) was performed
Muhammad Suhaeri et al.
Tissue engineering. Part A, 21(11-12), 1940-1951 (2015-04-04)
Extracellular matrices (ECM) obtained from in vitro-cultured cells have been given much attention, but its application in cardiac tissue engineering is still limited. This study investigates cardiomyogenic potential of fibroblast-derived matrix (FDM) as a novel ECM platform over gelatin or
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