Search Within
P4649
Applied Filters:
Keyword:'P4649'
Showing 1-30 of 190 results for "P4649" within Papers
B Chen et al.
The Journal of biological chemistry, 275(45), 34946-34953 (2000-08-17)
The envelope glycoprotein, gp160, of simian immunodeficiency virus (SIV) shares approximately 25% sequence identity with gp160 from the human immunodeficiency virus, type I, indicating a close structural similarity. As a result of binding to cell surface CD4 and co-receptor (e.g.
Jun Zhang et al.
The Journal of biological chemistry, 289(15), 10909-10918 (2014-02-28)
Acyl-CoA:monoacylglycerol acyltransferases (MGATs) and diacylglycerol acyltransferases (DGATs) catalyze the two consecutive steps in the synthesis of triacylglycerol, a key process required for dietary fat absorption into the enterocytes of the small intestine. In this report, we investigated the tendency of
Joe Sarkis et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(7), 3114-3123 (2014-04-03)
Mono- and digalactosyldiacylglycerol (MGDG and DGDG) are the most abundant lipids of photosynthetic membranes (thylakoids). In Arabidopsis green tissues, MGD1 is the main enzyme synthesizing MGDG. This monotopic enzyme is embedded in the inner envelope membrane of chloroplasts. DGDG synthesis
C Donnet et al.
The Journal of biological chemistry, 276(10), 7357-7365 (2000-12-02)
Thermal denaturation can help elucidate protein domain substructure. We previously showed that the Na,K-ATPase partially unfolded when heated to 55 degrees C (Arystarkhova, E., Gibbons, D. L., and Sweadner, K. J. (1995) J. Biol. Chem. 270, 8785-8796). The beta subunit
Phosphorylase Is Regulated by Allosteric Interactions and Reversible Phosphorylation
Berg JM, et al.
Biochemistry (2011)
T J Carty et al.
The Journal of biological chemistry, 250(13), 4980-4985 (1975-07-10)
A phosphopeptide which contains 14 residues including phosphoserine and which is derived from the NH2-terminal region of skeletal muscle glycogen phosphorylase (Nolan, C., Novoa, W. B., Krebs, E. G., and Fischer, E. H. (1964) Biochemistry 3, 542-551) has been shown
M Hirakawa et al.
British journal of cancer, 110(1), 156-163 (2013-11-21)
Transforming growth factor-β (TGF-β) is a major inducer of epithelial-mesenchymal transition (EMT) in different cell types. TGF-β-mediated EMT is thought to contribute to tumour cell spread and metastasis. Sialyl Lewis antigens synthesised by fucosyltransferase (FUT) 3 and FUT6 are highly
Atsushi Nakayama et al.
Organic letters, 16(13), 3572-3575 (2014-06-24)
Studies on the further development of the sequential glycosylations of the vancomycin aglycon catalyzed by the glycosyltransferases GtfE and GtfD and the observation of unusual, perhaps unexpected, aglycon substrate substituent effects on the rate and efficiency of the initial glycosylation
M A Martín et al.
Neuromuscular disorders : NMD, 10(6), 447-449 (2000-07-19)
We identified a novel missense mutation in the myophosphorylase gene (PYGM) in a Spanish patient with McArdle's disease. This homozygous C-to-A mutation results in the replacement of a highly conserved alanine at amino acid position 659 with an aspartic acid
Rucha S Sane et al.
The Journal of pharmacology and experimental therapeutics, 351(2), 403-412 (2014-09-11)
Faldaprevir, an investigational agent for hepatitis C virus treatment, is well tolerated but associated with rapidly reversible, dose-dependent, clinically benign, unconjugated hyperbilirubinemia. Multidisciplinary preclinical and clinical studies were used to characterize mechanisms underlying this hyperbilirubinemia. In vitro, faldaprevir inhibited key
Ximing Xu et al.
FEBS letters, 588(1), 138-142 (2013-11-26)
Muscle glycogen phosphorylase (GP) plays an important role in muscle functions. Mercury has toxic effects in skeletal muscle leading to muscle weakness or cramps. However, the mechanisms underlying these toxic effects are poorly understood. We report that GP is irreversibly
Rajindra P Aryal et al.
The Journal of biological chemistry, 289(17), 11630-11641 (2014-03-13)
Prior studies suggested that the core 1 β3-galactosyltransferase (T-synthase) is a specific client of the endoplasmic reticulum chaperone Cosmc, whose function is required for T-synthase folding, activity, and consequent synthesis of normal O-glycans in all vertebrate cells. To explore whether
Yasuo Yoshida et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 122(10), 951-960 (2014-03-19)
Streptococcus sanguinis is an early colonizer of tooth surfaces and forms biofilms with other species of microorganisms. In vitro, S. sanguinis produces water-soluble glucans from sucrose and releases them into the culture supernatant; however, the role played by these glucans
Congyi Zhu et al.
Biochemical and biophysical research communications, 455(3-4), 165-171 (2014-12-03)
Glucosylceramides (GlcCers) are important lipid components of the membrane systems of eukaryotes. Recent studies have suggested the roles for GlcCers in regulating fungal growth and pathogenesis. In this study, we report the identification and functional characterization of PdGcs1, a gene
J Gamez et al.
Muscle & nerve, 22(8), 1136-1138 (1999-07-27)
We have identified a novel missense mutation in the myophosphorylase gene in a Spanish patient with McArdle's disease. The patient was homozygous for a T-to-C transition at codon 115 (L115P) in exon 3, which changed an encoded leucine (CUG) to
J C Rubio et al.
Neuromuscular disorders : NMD, 9(3), 174-175 (1999-06-26)
We studied a pateint whose clinical, morphological and biochemical findings were consistent with McArdle's disease. Molecular genetic studies revealed that the patient did not harbor the common Arg49Stop mutation and was homozygous for the Gly204Ser mutation. Until now, no patient
Laura Travan et al.
The Journal of pediatrics, 165(1), 42-45 (2014-04-15)
To assess whether UGT1A1 promoter polymorphisms associated with Gilbert Syndrome (GS) occur with a greater frequency in neonates with severe hyperbilirubinemia. In a case-control study performed at a single hospital center in Italy, 70 case subjects with severe hyperbilirubinemia (defined
Rituparna Ganguly et al.
American journal of physiology. Cell physiology, 308(2), C111-C122 (2014-10-31)
Trivalent chromium (Cr(3+)) is a mineral nutrient reported to have beneficial effects in glycemic and cardiovascular health. In vitro and in vivo studies suggest that Cr(3+) supplementation reduces the atherogenic potential and lowers the risk of vascular inflammation in diabetes.
Paula Stettner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(24), 9998-10003 (2013-05-30)
Urinary ammonium excretion by the kidney is essential for renal excretion of sufficient amounts of protons and to maintain stable blood pH. Ammonium secretion by the collecting duct epithelia accounts for the majority of urinary ammonium; it is driven by
Xin Liu et al.
Die Pharmazie, 68(12), 945-950 (2014-01-10)
The aim of the present study was to investigate arbidol's inhibition towards UDP-glucuronosyltransferase (UGT) 1A9 and 2B7. The nonspecific probe substrate 4-methylumbelliferone (4-MU) and recombinant UGT enzymes (UGT1A9, UGT2B7) were firstly used to evaluate the inhibition of arbidol towards UGT1A9
P K Hwang et al.
European journal of biochemistry, 152(2), 267-274 (1985-10-15)
As an initial step in the investigation of the structure, evolution and developmental regulation of the glycogen phosphorylase gene family, we have isolated partial cDNAs to rat, rabbit and human muscle phosphorylase mRNAs. Sequence comparisons of these cDNAs in regions
Juri Sadahiro et al.
Biochemical and biophysical research communications, 456(1), 500-505 (2014-12-10)
Gluconobacter oxydans ATCC 11894 produces dextran dextrinase (DDase, EC 2.4.1.2), which synthesizes dextran from the starch hydrolysate, dextrin and is known to cause ropy beer. G. oxydans ATCC 11894 was believed to possess both a secreted DDase (DDext) and an
Urike Beckert et al.
Biochemical and biophysical research communications, 450(1), 870-874 (2014-06-28)
In addition to the well known second messengers cAMP and cGMP, mammalian cells contain the cyclic pyrimidine nucleotides cCMP and cUMP. Soluble guanylyl cyclase and soluble adenylyl cyclase produce all four cNMPs. Several bacterial toxins exploit mammalian cyclic nucleotide signaling.
Katherine G Meilleur et al.
Journal of neuropathology and experimental neurology, 73(5), 425-441 (2014-04-09)
Dystroglycanopathies are a subtype of congenital muscular dystrophy of varying severity that can affect the brain and eyes, ranging from Walker-Warburg syndrome with severe brain malformation to milder congenital muscular dystrophy presentations with affected or normal cognition and later onset.
Sylvia Hartmann et al.
British journal of haematology, 167(2), 238-242 (2014-06-27)
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare lymphoma entity. We performed a matched-pair analysis to evaluate the prognostic impact of several histopathological features in this distinct Hodgkin lymphoma subtype. Lymph node samples of NLPHL patients were tested for CD15
A simple method for the preparation of crystalline potato phosphorylase and Q-enzyme.
H BAUM et al.
Nature, 171(4361), 983-984 (1953-05-30)
Daniel Foshag et al.
Biochimica et biophysica acta, 1844(9), 1619-1630 (2014-06-25)
Escherichia coli C-glycosyltransferase IroB catalyzes the formation of a CC bond between enterobactin and the glucose moiety of UDP-glucose, resulting in the production of mono-, di- and tri-glucosylated enterobactin (MGE, DGE, TGE). To identify catalytic residues, we generated a homology
Kris Gevaert et al.
Nature biotechnology, 21(5), 566-569 (2003-04-01)
Current non-gel techniques for analyzing proteomes rely heavily on mass spectrometric analysis of enzymatically digested protein mixtures. Prior to analysis, a highly complex peptide mixture is either separated on a multidimensional chromatographic system or it is first reduced in complexity
Ayako Kurimoto et al.
The Journal of biological chemistry, 289(17), 11704-11714 (2014-03-13)
Glycans play key roles in a variety of protein functions under normal and pathological conditions, but several glycosyltransferase-deficient mice exhibit no or only mild phenotypes due to redundancy or compensation of glycan functions. However, we have only a limited understanding
John Janetzko et al.
The Journal of biological chemistry, 289(50), 34424-34432 (2014-10-23)
O-GlcNAc transferase is an essential mammalian enzyme responsible for transferring a single GlcNAc moiety from UDP-GlcNAc to specific serine/threonine residues of hundreds of nuclear and cytoplasmic proteins. This modification is dynamic and has been implicated in numerous signaling pathways. An
Page 1 of 7