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Showing 1-30 of 40 results for "P5884" within Papers
Sreekhar Cheboyina et al.
International journal of pharmaceutics, 359(1-2), 167-173 (2008-05-23)
A novel freeze pelletization technique was evaluated for the preparation of wax-based sustained release matrix pellets. Pellets containing water-soluble drugs were successfully prepared using a variety of waxes. The drug release significantly depended on the wax type used and the
H Yeşim Karasulu et al.
AAPS PharmSciTech, 9(2), 342-348 (2008-04-24)
The purpose of this research was to develop an emulsion formulation of indomethacin (IND) suitable for nasal delivery. IND was incorporated into the oil phases of oil in water (O/W) and water in oil (W/O) emulsions. For this purpose, different
Anja Heins et al.
Lipids, 42(6), 561-572 (2007-04-21)
The location and the resulting chemical microenvironment of the antioxidant propyl gallate (PG) was studied in micellar solutions using the cationic emulsifier cetyl trimethyl ammonium bromide (CTAB), the anionic emulsifier sodium dodecyl sulphate (SDS) and the non-ionic emulsifier Brij 58
Study of surface and solution properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons
Panda
Journal of Molecular Liquids, 163, 6-6 (2011)
G Tataru et al.
International journal of pharmaceutics, 404(1-2), 83-93 (2010-11-16)
Magnetic micro- and nanoparticles based on ferrofluid (maghemite) were elaborated by inverse emulsion crosslinking of sodium salt of carboxymethylcellulose (CMCNa) and gelatin. Crosslinking was carried out with glutaric aldehyde within aqueous droplets dispersed into toluene in presence of surfactants. The
Carla Cerqueira et al.
Molecular therapy. Methods & clinical development, 5, 165-179 (2017-05-13)
Papillomavirus capsids can package a wide variety of nonviral DNA plasmids and deliver the packaged genetic material to cells, making them attractive candidates for targeted gene delivery vehicles. However, the papillomavirus vectors generated by current methods are unlikely to be
Yuji Ishii et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(11), 2081-2089 (2012-08-02)
We have suggested that adenine-related compounds are allosteric inhibitors of UGT in rat liver microsomes (RLM) treated with detergent. To clarify whether the same occurs with a pore-forming peptide, alamethicin, the effects of adenine-related compounds on 4-metylumbelliferone (4-MU) glucuronidation were
Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure
Foley, P., et al
Biochemical and Biophysical Research Communications, 395, 6-6 (2010)
Lucia Montenegro et al.
Drug development and industrial pharmacy, 37(6), 737-746 (2011-01-06)
Solid lipid nanoparticles (SLN) are regarded as interesting drug delivery systems and their preparation techniques have gained a great deal of attention. To evaluate the feasibility of preparing idebenone (IDE) loaded SLN from O/W microemulsions by the phase-inversion temperature (PIT)
J Sýkora et al.
Biochimica et biophysica acta, 1788(2), 324-332 (2008-12-17)
The effect of non-ionic detergents on baclofen (GABAB-R agonist)-stimulated G-protein activity was measured as a [(35)S]GTPgammaS binding assay in the plasma membranes (PM) isolated from the brain tissue. The effect was clearly biphasic--a decrease in the activity was followed by
Mika Kaakinen et al.
Experimental cell research, 314(2), 237-245 (2007-11-15)
The relationship between the endoplasmic reticulum (ER) and the sarcoplasmic reticulum (SR) of skeletal muscle cells has remained obscure. In this study, we found that ER- and SR-specific membrane proteins exhibited diverse solubility properties when extracted with mild detergents. Accordingly
Yuxun Zhang et al.
Protein expression and purification, 59(2), 249-257 (2008-04-01)
Obtaining sufficient amount of purified G-protein coupled receptors (GPCRs) is almost always one of the major challenges for their structural studies. CB2(271-326), a human cannabinoid receptor 2 (CB2) fragment comprising part of the third extracellular loop (EL3), the seventh transmembrane
Samata Mehta et al.
International journal of pharmaceutics, 426(1-2), 44-53 (2012-01-24)
For any new vaginal dosage form, the distribution and retention in the vagina has to be assessed by in vivo evaluation. We evaluated the vaginal distribution and retention of starch-based pellets in sheep as live animal model by gamma scintigraphy
Troy J Kemp et al.
Human vaccines & immunotherapeutics, 11(2), 337-346 (2015-02-20)
To assess immunogenicity and development of antibodies in the context of vaccination, it is critical to quantify titers of neutralizing antibodies. We have been employing the 293TT cell-based neutralization assay system to quantify anti-HPV neutralizing antibodies. In this system, human
Xue Li et al.
Chemosphere, 78(6), 752-759 (2009-12-17)
Currently, soil contamination by polybrominated diphenyl ethers (PBDEs) at e-waste recycling sites in China is of significant environmental concern and requires the identification of appropriate remediation technologies. In this paper, photodestruction of a model PBDE congener (BDE-99) in selected UV/surfactant
Woraporn Sukhumavasi et al.
Journal of immunology (Baltimore, Md. : 1950), 181(5), 3464-3473 (2008-08-21)
TLR adaptor MyD88 activation is important in host resistance to Toxoplasma gondii during i.p. infection, but the function of this signaling pathway during oral infection, in which mucosal immunity assumes a predominant role, has not been examined. In this study
Photodestruction of BDE-99 in micellar solutions of nonionic surfactants of Brij 35 and Brij 58
Li, X., et al.
Chemosphere, 78, 8-8 (2010)
F Johansson et al.
The Plant journal : for cell and molecular biology, 7(1), 165-173 (1995-01-01)
Most of the plasma membrane vesicles formed upon homogenization of plant tissue have a right-side-out (cytoplasmic side-in) orientation. Subsequent purification of plasma membrane vesicles using aqueous two-phase partitioning leads to a further enrichment in right-side-out vesicles resulting in preparations with
Valquíria T Arantes et al.
Colloids and surfaces. B, Biointerfaces, 188, 110749-110749 (2020-01-14)
Repair of tissue damaged in diabetic wounds is essential to minimize the cases of amputation of the limbs in millions of diabetic people around the world. Although the all-trans retinoic acid (ATRA) is described as a potential wound healing agent
Preparation of extracts from yeast.
S M Jazwinski
Methods in enzymology, 182, 154-174 (1990-01-01)
Ping Wang et al.
Frontiers in oncology, 10, 571181-571181 (2020-11-13)
Psychological stress is closely related to the occurrence and prognosis of various malignant tumors, but the underlying mechanisms are not well studied. CD147 has been reported to be expressed in glioma and other malignant tumors. CD147 not only participates in
Sayan Gupta et al.
Biochemistry, 46(35), 9886-9898 (2007-08-09)
Recombinant full-length Saccharomyces cerevisiae TATA binding protein (TBP) and its isolated C-terminal conserved core domain (TBPc) were prepared with measured high specific DNA-binding activities. Direct, quantitative comparison of TATA box binding by TBP and TBPc reveals greater affinity by TBPc
Anders Pedersen et al.
Protein expression and purification, 77(2), 220-223 (2011-02-15)
The anti-apoptotic B cell CLL/lymphoma-2 (Bcl-2) protein is a key player in the regulation of programmed cell death and is linked to various types of cancer and their resistance to drug treatment. Biophysical and structural studies of the full-length intact
Prasun Bandyopadhyay et al.
The journal of physical chemistry. B, 114(35), 11462-11467 (2010-08-19)
The fluorescence response of pyrene has been studied in the presence of nonionic brij micelles and poly(acrylic acid) (PAA) with benzophenone (BP) as a neutral hydrophobic quencher. Pyrene emission is quenched ("off" state) in the presence of BP in brij
Lucia Montenegro et al.
International journal of pharmaceutics, 434(1-2), 169-174 (2012-06-05)
Idebenone (IDE), a synthetic derivative of ubiquinone, shows a potent antioxidant activity that could be beneficial in the treatment of skin oxidative damages. In this work, the feasibility of targeting IDE into the upper layers of the skin by topical
Koichi Tamano et al.
Journal of biotechnology, 248, 9-14 (2017-03-17)
Free fatty acids (FFAs) are useful for generating biofuel compounds and functional lipids. Microbes are increasingly exploited to produce FFAs via metabolic engineering. However, in many microorganisms, FFAs accumulate in the cytosol, and disrupting cells to extract them is energy
Patricia L Foley et al.
Biochemical and biophysical research communications, 395(1), 42-47 (2010-03-30)
The shape and compaction of the bacterial nucleoid may affect the accessibility of genetic material to the transcriptional machinery in natural and synthetic systems. To investigate this phenomenon, the nature and contribution of RNA and protein to the compaction of
William Bragg et al.
Journal of chromatography. A, 1218(48), 8691-8700 (2011-11-01)
A novel procedure was developed for the fabrication of a fritless packed column for the coupling of capillary electrochromatography (CEC) to mass spectrometry (MS). The process involved the formation of internal tapers on two separate columns. Once the internal tapers
M Kellermayer et al.
Journal of cellular physiology, 159(2), 197-204 (1994-05-01)
The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent
Chuanyu Yang et al.
PloS one, 10(7), e0133826-e0133826 (2015-07-25)
Huanglongbing (HLB) is the most serious disease affecting the citrus industry worldwide to date. The causal agent, Candidatus Liberibacter asiaticus (Las), resides in citrus phloem, which makes it difficult to effectively treat with chemical compounds. In this study, a transcuticular
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